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公开(公告)号:EP2231137A4
公开(公告)日:2011-04-06
申请号:EP08871016
申请日:2008-12-18
申请人: YANG DAN , LI XIANG , SHEN BING , YAO XIAO-QIANG , THE CHINESE UNIVERSITY OF HONG KONG , VERSITECH LTD
发明人: YANG DAN , LI XIANG , SHEN BING , YAO XIAO-QIANG
IPC分类号: A61K31/16 , A61K31/215 , A61K31/4412 , A61P9/12 , A61P13/12 , A61P19/08 , A61P25/00 , A61P25/08 , A61P25/14 , A61P27/00 , C07C217/46 , C07C217/48 , C07C225/08 , C07C225/14 , C07C225/16 , C07C237/42 , C07C239/14 , C07C239/20 , C07D213/63 , C07D213/79 , C07D213/81
CPC分类号: A61K31/166
摘要: Provided herein are methods of modulating membrane potential of a cell membrane using self-assembling compounds. Also provided herein are methods of regulating a natural voltage-dependent ion channel in a cell membrane using the self-assembling compounds disclosed herein. Further provided herein are methods of treating, preventing and/or managing a disease that is related to the abnormal membrane potential responses by using the self-assembling compounds disclosed herein.