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公开(公告)号:EP4144765A1
公开(公告)日:2023-03-08
申请号:EP21797718.0
申请日:2021-04-30
发明人: ZHANG, Yali , WANG, Shaojuan , WU, Yangtao , HOU, Wangheng , YE, Jianghui , WANG, Juan , ZHANG, Tianying , CHENG, Tong , YUAN, Quan , XIA, Ningshao
摘要: Disclosed are a fusion protein probe and a cell model for screening a blocking agent of coronavirus infections, a screening system comprising same, and a method of using the screening system for screening a blocking agent of coronavirus infections. The screening system and method do not involve live viruses, are simple and convenient to operate, have a high accuracy, are suitable for high throughput screening, and are of great significance for the development of coronavirus neutralizing antibodies, preventive vaccines, and small molecule drugs.