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1.发明公开Method for determining the result of an agglutination reaction and microplate for determining products of agglutination reactions 审中-公开一种用于确定用于确定凝集反应的产物凝集反应和微孔板的结果的方法
公开(公告)号：EP2859948A1
公开(公告)日：2015-04-15
申请号：EP14152860.4
申请日：2014-01-28
发明人： Mann, Wolfgang , Wang, Zhaoqiang
IPC分类号： B01L3/00 , G01N21/00 , G01N33/543
CPC分类号： G01N33/5304 , B01L3/5025 , B01L2200/16 , B01L2300/069 , B01L2300/0829 , B01L2300/0858 , B01L2400/0409 , G01N21/253 , G01N21/82 , G01N33/54366
摘要： Agglutinated and non-agglutinated sample material is separated by means of a separation material such as gel material or a bead matrix in a centrifugation step. Whether an agglutination reaction took place or not is determined by comparing the color intensities and/or the gray levels of images of the top side and the bottom side of the respective reaction vessel. Comparing the color intensities and/or the gray levels of the two images makes the automatic determination reliable and stable. Furthermore, the reaction wells are arranged in a two-dimensional array which provides a high throughput.
摘要翻译： 凝集和非凝集的样品材料通过分离材料的方法分离：例如凝胶材料或在离心步骤珠基质。 是否对凝集反应进行与否确定性通过比较颜色强度和/或顶侧的图像的灰度级和respectivement反应容器的底部侧开采。 比较颜色强度和/或两个图像的灰度级，使自动判定可靠和稳定的。 进一步，反应孔被布置成二维阵列，其提供高吞吐量。
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2.发明公开Centrifuge and method for centrifuging a reaction vessel unit 有权Zentrifuge und Verfahren zum Zentrifugieren einerReaktionsgefäßeinheit
公开(公告)号：EP2835178A1
公开(公告)日：2015-02-11
申请号：EP13179437.2
申请日：2013-08-06
CPC分类号： G01N33/54326 , B01L99/00 , B01L2300/0829 , B01L2400/0409 , B03C1/002 , B03C1/01 , B03C1/288 , B03C1/30 , B03C2201/18 , B03C2201/26 , B04B5/0407 , B04B5/0414 , B04B7/04 , B04B15/02 , B04B2011/046 , B08B3/02 , B08B3/04 , B08B3/06 , B08B3/10 , B08B9/00 , G01N33/54366 , G01N35/028 , G01N2035/0437
摘要： The invention relates to a centrifuge for cleaning, washing or centrifuging a reaction vessel unit comprising
a rotor (8) for holding at least one reaction vessel unit (2) with its opening(s) directed radially outwardly or radially inwardly,
a motor for rotating the rotor (8) around a rotation axis (18),
a housing (23).
The centrifuge is characterized by a small gap between the rotor and the housing, or a cooling device for cooling an inner surface of the housing, or a loading mechanism comprising a flexible elongate beam (34) for extension and retraction of a reaction vessel unit (2).摘要翻译： 本发明涉及一种用于清洁，洗涤或离心反应容器单元的离心机，该离心机包括用于保持至少一个反应容器单元（2）的转子（8），其中其开口径向向外或径向向内指向，旋转的马达 围绕旋转轴线（18）的转子（8），壳体（23）。 离心机的特征在于转子和壳体之间的小间隙，或用于冷却壳体内表面的冷却装置，或包括柔性细长梁（34）的装载机构，用于使反应容器单元（ 2）。
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公开(公告)号：EP3326718A1
公开(公告)日：2018-05-30
申请号：EP18151225.2
申请日：2014-10-07
发明人： Mann, Wolfgang , Wang, Zhaoqiang
IPC分类号： B01L3/00 , G01N21/00 , G01N33/543
CPC分类号： G01N33/5304 , B01L3/5025 , B01L2200/16 , B01L2300/069 , B01L2300/0829 , B01L2300/0858 , B01L2400/0409 , G01N21/253 , G01N21/82 , G01N33/54366
摘要： The invention relates to a microplate used in a method for determining the result of an agglutination reaction.
Agglutinated and non-agglutinated sample material is separated by means of a separation material such as gel material or a bead matrix in a centrifugation step. Whether an agglutination reaction took place or not is determined by comparing the color intensities and/or the gray levels of images of the top side and the bottom side of the respective reaction vessel. Comparing the color intensities and/or the gray levels of 20 the two images makes the automatic determination reliable and stable. Furthermore, the reaction wells are arranged in a two-dimensional array which provides a high throughput.-
公开(公告)号：EP2835178B1
公开(公告)日：2017-04-12
申请号：EP13179437.2
申请日：2013-08-06
CPC分类号： G01N33/54326 , B01L99/00 , B01L2300/0829 , B01L2400/0409 , B03C1/002 , B03C1/01 , B03C1/288 , B03C1/30 , B03C2201/18 , B03C2201/26 , B04B5/0407 , B04B5/0414 , B04B7/04 , B04B15/02 , B04B2011/046 , B08B3/02 , B08B3/04 , B08B3/06 , B08B3/10 , B08B9/00 , G01N33/54366 , G01N35/028 , G01N2035/0437
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5.发明公开Method for carrying out a ligand binding assay and device for carrying out such a method 审中-公开一种用于执行配体结合测定和装置用于实现这样的方法的方法
公开(公告)号：EP2985603A1
公开(公告)日：2016-02-17
申请号：EP14180879.0
申请日：2014-08-13
发明人： Wang, Zhaoqiang , Mann, Wolfgang
IPC分类号： G01N33/543
CPC分类号： G01N33/54366
摘要： Method for carrying out a ligand binding assay in at least one reaction well, comprising the steps of filling the at least one reaction well with a sample liquid and overlaying the sample liquid with an oil film.
摘要翻译： 用于在至少一个反应进行配体结合测定孔，将包含与样品液填充所述至少一个反应孔中，在电影与油覆盖的样品液体的步骤方法。
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公开(公告)号：EP3326718B1
公开(公告)日：2019-08-14
申请号：EP18151225.2
申请日：2014-10-07
发明人： Mann, Wolfgang , Wang, Zhaoqiang
IPC分类号： B01L3/00 , G01N21/00 , G01N33/543
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公开(公告)号：EP2929939A1
公开(公告)日：2015-10-14
申请号：EP14163772.8
申请日：2014-04-07
发明人： Mann, Wolfgang , Wang, Zhaoqiang
CPC分类号： B01L3/5025 , B01J2219/00315 , B01J2219/00317 , B01L3/508 , B01L3/5085 , B01L3/50855 , B01L9/523 , B01L2200/028 , B01L2200/12 , B01L2300/0636 , B01L2300/0819 , B01L2300/0829 , B01L2300/0851 , B01L2300/0858 , B01L2300/123 , B01L2400/0409 , G01N21/07 , G01N33/80 , G01N35/028 , G01N35/04 , G01N2035/0449
摘要： The invention relates to a microplate comprising a plurality of wells arranged in a two-dimensional array, wherein each well is inclinable or pivotably mounted in the microplate so that the wells align with the direction of a centrifugal force during centrifuging of the microplate.
摘要翻译： 本发明涉及一种微孔板，其包括以二维阵列排列的多个孔，其中每个孔可倾斜或可枢转地安装在微板中，使得孔在离心微孔板期间与离心力的方向对准。
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