TREATMENT OF CNS INFLAMMATORY DISORDERS
    4.
    发明公开
    TREATMENT OF CNS INFLAMMATORY DISORDERS 审中-公开
    治疗中枢神经炎性疾病

    公开(公告)号:EP3215178A1

    公开(公告)日:2017-09-13

    申请号:EP15856506.9

    申请日:2015-11-05

    IPC分类号: A61K38/21 A61K9/00

    摘要: A method of upregulating an anti-inflammatory response in a central nervous system (CNS) of a subject in need thereof is disclosed. The method comprising locally administering to the CNS of the subject a therapeutically effective amount of IFN-beta, thereby upregulating the anti-inflammatory response in the CNS of the subject. Methods of treating an inflammation in a CNS or treating a disease, disorder, condition or injury of a CNS of a subject are also disclosed.

    摘要翻译: 公开了上调有需要的受试者的中枢神经系统(CNS)中的抗炎反应的方法。 该方法包括向受试者的CNS局部施用治疗有效量的IFN-β,从而上调受试者CNS中的抗炎反应。 还公开了治疗CNS中的炎症或治疗受试者的CNS的疾病,病症,病症或损伤的方法。

    METHODS AND KITS FOR ANALYZING DNA BINDING MOIETIES ATTACHED TO DNA
    7.
    发明公开
    METHODS AND KITS FOR ANALYZING DNA BINDING MOIETIES ATTACHED TO DNA 审中-公开
    VERFAHREN UND KITS ZUR ANALYZE VON AN DNAANGEHÄNGTENDNA-BINDUNGSTEILEN

    公开(公告)号:EP3132057A1

    公开(公告)日:2017-02-22

    申请号:EP15723307.3

    申请日:2015-04-16

    IPC分类号: C12Q1/68 G01N33/52 G01N33/53

    摘要: A method of analyzing DNA which, in a cell, is bound to a DNA binding moiety, the method comprising: (a) obtaining at least two samples of complexes of DNA bound to a DNA binding moiety; (b) isolating the complexes on a solid support; (c) labeling the DNA of the complexes, wherein the labeling distinguishes between the complexes of the first of the at least two samples and the complexes of the second of the at least two samples; (d) pooling the at least two samples of complexes; and (e) isolating the complexes using an agent which specifically binds to the DNA binding moiety; and (f) analyzing the DNA of the complexes.

    摘要翻译: 一种分析在细胞中与DNA结合部分结合的DNA的方法,所述方法包括:(a)获得至少两个与DNA结合部分结合的DNA的复合物样品; (b)在固体支持物上分离复合物; (c)标记复合物的DNA,其中所述标记区分所述至少两个样品中的第一个样品的复合物和所述至少两个样品中的第二个样品的复合物; (d)汇集至少两个复合物样品; 和(e)使用特异性结合DNA结合部分的试剂分离复合物; 和(f)分析复合物的DNA。