利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

7 条记录 (耗时 0.017 秒)

    LIPOSOMES-CONTAINING ANTIFOULING COMPOSITIONS AND USES THEREOF
    3.
    发明公开
    LIPOSOMES-CONTAINING ANTIFOULING COMPOSITIONS AND USES THEREOF 审中-公开
    含脂质体的防污组合物及其用途

    公开(公告)号：EP3200585A1

    公开(公告)日：2017-08-09

    申请号：EP15794317.6

    申请日：2015-10-01

    申请人： Yeda Research and Development Co., Ltd.

    发明人： KLEIN, Jacob ,  GOLDBERG, Ronit ,  LIN, Weifeng ,  JAHN, Sabrina

    IPC分类号： A01N25/26 ,  A61K31/717 ,  A61K31/765

    摘要： A method of inhibiting adsorption of a biofouling-promoting agent on a surface of a substrate and a method of inhibiting biofilm formation on a surface of a substrate are disclosed herein. The methods comprise comprising contacting the substrate with a composition which comprises liposomes. Further disclosed herein is a composition comprising liposomes, identified for use in inhibiting adsorption of a biofouling-promoting agent on a surface of a substrate and/or inhibiting biofilm formation on a surface of a substrate. Further disclosed are articles comprising a substrate and a composition described herein being applied on a surface of the substrate, and a method of treating keratitis in a contact lens-wearing subject, by rinsing and/or immersing a contact lens in a solution comprising liposomes.

    摘要翻译： 本文公开了一种抑制生物附着促进剂在基质表面上的吸附的方法和抑制基质表面上生物膜形成的方法。 该方法包括使底物与包含脂质体的组合物接触。 本文进一步公开了包含脂质体的组合物，所述脂质体经鉴定用于抑制生物污垢促进剂在基质表面上的吸附和/或抑制基质表面上的生物膜形成。 进一步公开了包含本文所述的基质和组合物的制品施用在基质表面上的制品，以及通过漂洗和/或将隐形眼镜浸入包含脂质体的溶液中来治疗戴隐形眼镜的受试者中的角膜炎的方法。

    LIPID ANALOGS AND LIPOSOMES COMPRISING SAME
    5.
    发明公开
    LIPID ANALOGS AND LIPOSOMES COMPRISING SAME 审中-公开

    公开(公告)号：EP4230632A3

    公开(公告)日：2023-10-25

    申请号：EP23158674.4

    申请日：2016-12-22

    申请人： Yeda Research and Development Co. Ltd

    发明人： KLEIN, Jacob ,  LIN, Weifeng ,  GOLDBERG, Ronit

    IPC分类号： C07F9/10 ,  C08F10/00

    摘要： The present invention refers to a polymeric compound having the general formula I:

    wherein:
    m is zero or a positive integer;
    n is an integer which is at least 1, wherein when X does not comprise a phosphate group, n is at least 2;
    X is a lipid moiety;
    Y is a backbone unit which forms a polymeric backbone;
    L is absent or is a linking moiety; and
    Z has the general formula II:

    wherein:
    A is a substituted or unsubstituted hydrocarbon;
    B is an oxygen atom or is absent; and
    R 1 -R 3 are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, heteroalicyclic, aryl and heteroaryl,

    and wherein:
    said lipid is selected from the group consisting of a fatty acid, a monoglyceride, a diglyceride, a triglyceride, a glycerophospholipid, a sphingolipid, and a sterol; and/or
    said lipid moiety comprises at least one fatty acid moiety selected from the group consisting of lauroyl, myristoyl, palmitoyl, stearoyl, palmitoleoyl, oleoyl, and linoleoyl.

    LIPID ANALOGS AND LIPOSOMES COMPRISING SAME
    6.
    发明公开
    LIPID ANALOGS AND LIPOSOMES COMPRISING SAME 审中-公开

    公开(公告)号：EP4230632A2

    公开(公告)日：2023-08-23

    申请号：EP23158674.4

    申请日：2016-12-22

    申请人： Yeda Research and Development Co. Ltd

    发明人： KLEIN, Jacob ,  LIN, Weifeng ,  GOLDBERG, Ronit

    IPC分类号： C07F9/10 ,  C08F10/00

    摘要： The present invention refers to a polymeric compound having the general formula I:

    wherein:
    m is zero or a positive integer;
    n is an integer which is at least 1, wherein when X does not comprise a phosphate group, n is at least 2;
    X is a lipid moiety;
    Y is a backbone unit which forms a polymeric backbone;
    L is absent or is a linking moiety; and
    Z has the general formula II:

    wherein:
    A is a substituted or unsubstituted hydrocarbon;
    B is an oxygen atom or is absent; and
    R 1 -R 3 are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, heteroalicyclic, aryl and heteroaryl,

    and wherein:
    said lipid is selected from the group consisting of a fatty acid, a monoglyceride, a diglyceride, a triglyceride, a glycerophospholipid, a sphingolipid, and a sterol; and/or
    said lipid moiety comprises at least one fatty acid moiety selected from the group consisting of lauroyl, myristoyl, palmitoyl, stearoyl, palmitoleoyl, oleoyl, and linoleoyl.