公开(公告)号：EP2889373A1

公开(公告)日：2015-07-01

申请号：EP14196176.3

申请日：2014-12-04

申请人： Yeditepe Universitesi

发明人： Sahin, Fikrettin ,  Tasli, Pakize Neslihan

IPC分类号： C12N5/077

CPC分类号： C12N5/0654 ,  C12N2500/05 ,  C12N2500/14 ,  C12N2500/38 ,  C12N2500/42 ,  C12N2500/50 ,  C12N2501/30 ,  C12N2501/39 ,  C12N2506/1361

摘要： The present invention relates to a dental differentiation product which obtains tooth cell from adult stem cells. Tooth cells are effectively obtained with adult stem cells that are used in tissue engineering. When stems cells are differentiating, they lose their own properties and acquire new properties. These properties are both at morphological level and gene expression level. The product of the present invention comprises C 13 H 16 N 2 O) (melatonin), Ca(OH) 2 (calcium hydroxide), C 22 H 29 FOs (dexamethasone), C 3 H 7 Na 2 O 6 P ·5H 2 O (disodium beta-glycerophosphate hydrate), NaF (sodium fluoride) and Pluronic chemicals.

摘要翻译： 本发明涉及从成体干细胞获得牙细胞的牙齿分化产物。 用组织工程中的成体干细胞有效地获得牙细胞。 当干细胞分化时，它们失去自己的属性并获得新的特性。 这些性质都处于形态学水平和基因表达水平。 本发明的产品包括C 13 H 16 N 2 O）（褪黑激素），Ca（OH）2（氢氧化钙），C 22 H 29 FO（地塞米松），C 3 H 7 Na 2 O 6 P·5H 2 O（磷酸二氢钠水合物二钠），NaF（氟化钠）和Pluronic化学品。