专利检索 ap:("ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI") AND inv:"GOMI, Shuichi" 第 1 页

1.

发明公开
D-B-LYSYLMETHANEDIAMINE DERIVATIVES WITH BACTERIA, AIDS VIRUS AND TUMOR CELL GROWTH INHIBITING ACTIVITY AND PREPARATION THEREOF 失效
标题翻译： WITH INHIBITIERENDEN EFFECT D-B-lysylmethanediamine衍生物对细菌，艾滋病病毒和肿瘤细胞生长及生产

公开(公告)号：EP0777644A1

公开(公告)日：1997-06-11

申请号：EP95929220.0

申请日：1995-08-24

申请人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI

发明人： KONDO, Shinichi Royal Heights Minami-Rokugo 608 , IKEDA, Yoko Crescent Ikejiri Ohashi 502 , TAKEUCHI, Tomio New Fuji Mansion 701 , SHINEI, Rie , GOMI, Shuichi , SHIBAHARA, Seiji , HOSHINO, Hiroo

IPC分类号： A61K31 , A61P31 , A61P37 , C07C231 , C07C237

CPC分类号： C07C237/10

摘要： Now are provided (R)-3,6-diamino-N-(φ-aminoalkyl)-hexanamides which are novel compounds having general formula (I), wherein n stands for 2-5, and which may be for example, (R)-3,6-diamino-N-(2-aminoethyl)hexanamide (n = 2) and (R)-3,6-diamino-N-(3-aminopropyl)hexanamide (n = 3). Their preparation process is also provided. These novel compounds and acid addition salts thereof have activities inhibitory against Gram-positive bacteria, Gram-negative bacteria and AIDS virus, as well as tumor cells and are chemically stable. These novel compounds and their salts are useful as chemotherapeutic agents for diseases caused by these bacteria or virus and also as antitumor agent.