摘要:
A tylosin derivative represented by the general formula wherein R. represents a hydrogen atom or a hydroxyl group and R. represents (wherein R 9 and R 10 may be the same or different and selected from a hydrogen atom and C, to C. alkyl groups or which may together form an alkylene group having 3-7 carbon atoms) or -S-R 11 (wherein R " represents a furanyl group or a pyridyl group).
摘要:
Mycaminosyl tylonolide derivatives represented by the following general formula (wherein R 1 is a hydroxyl, lower alkanoyloxy, benzoyloxy, or azido group, or an amino group optionally substituted with lower alkyl and/or lower alkanoyl group(s); R 2 is a hydrogen atom or hydroxyl group; R 3 is a hydrogen atom or formyl group; and means a double bond or the group ), and salts thereof. These compounds have antibacterial activity.
摘要:
Novel 23-C-substituted mycaminosyl tylonolide of the general formula (I) wherein R 1 represents a lower alkyl group, an aryl group, a lower alkenyl group or a lower alkinyl group, R 2 represents a hydrogen atom or a hydroxyl group. These compounds have excellent antibacterial activities.