公开(公告)号：EP2947075A4

公开(公告)日：2015-12-30

申请号：EP13874792

申请日：2013-02-05

申请人： ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD

发明人： SU YEHUA ,  CAI GUOPING ,  YANG ZHENGHE ,  CHEN BANGCHI

IPC分类号： C07D285/13

CPC分类号： C07D285/13

公开(公告)号：EP3222606A4

公开(公告)日：2018-01-10

申请号：EP15864805

申请日：2015-09-25

申请人： ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD

发明人： SU YEHUA ,  SHI JIEPING ,  LU JIANXIN ,  ZHANG TIANHAO ,  YU XIAOHUA ,  CAI GUOPING ,  CHEN BANGCHI

IPC分类号： C07C51/285 ,  C07B41/08 ,  C07C53/08 ,  C07C201/12 ,  C07C205/11 ,  C07C205/56 ,  C07C205/58 ,  C07C253/30 ,  C07C315/04 ,  C07C317/44 ,  C07D213/60 ,  C07D213/79 ,  C07D213/803

CPC分类号： C07C51/285 ,  C07B41/08 ,  C07C53/08 ,  C07C201/12 ,  C07C205/58 ,  C07C253/30 ,  C07C315/04 ,  C07C317/44 ,  C07D213/60 ,  C07D213/79 ,  C07D213/803 ,  C07C205/56 ,  C07C205/11 ,  C07C255/41

摘要： A preparative method for carboxylic acids is disclosed in the present invention. The method is characterized in that: compounds (II) are reacted in the presence of hydrogen peroxide and base to produce target products (I), as represented by the following reaction scheme: wherein R 1 is aryl, pyridyl, pyrimidyl, pyridazinyl, pyrazinyl, benzothienyl, benzofuranyl, quinolinyl, isoquinolinyl, thiadiazolyl, C 1-6 alkyl, C 3-6 cycloalkyl, C 2-6 alkenyl, C 2-6 alkynyl and hydrogen; R 2 is alkoxycarbonyl, alkylaminocarbonyl, aminocarbonyl, alkylthiolcarbonyl, cyano, sulfonyl, sulfinyl, carbonyl, aldehyde, carboxyl, nitro, alkyl and hydrogen; R 3 is alkoxycarbonyl, alkyl amido carbonyl, aminocarbonyl, cyano, sulfonyl, sulfinyl, carbonyl, carboxyl and nitro. The present invention has the following main benefits: cheap and readily available starting materials, safe processes, high yield, good quality, which facilitates industrial production.