专利检索 ap:("ZYMOGENETICS, INC." OR "THE UNIVERSITY OF WASHINGTON") AND inv:"KENAGY, Richard D." 第 1 页

1.

发明公开
INHIBITION OF INTIMAL HYPERPLASIA USING ANTIBODIES TO PDGF RECEPTORS 失效
标题翻译： INNER增生的抑制使用ANTIKÖEPERNTO PDGF受体

公开(公告)号：EP0686044A1

公开(公告)日：1995-12-13

申请号：EP94909627.0

申请日：1994-02-17

申请人： ZYMOGENETICS, INC. , THE UNIVERSITY OF WASHINGTON

发明人： HART, Charles E. , KENAGY, Richard D. , CLOWES, Alexander W.

IPC分类号： C12N15 , A61K31 , A61K39 , A61P7 , A61P9 , A61P43 , C07K16 , C12P21 , A61K38 , C12R1

CPC分类号： C07K16/2863 , A61K38/00 , A61K39/395 , C07K2317/24 , C07K2319/30 , C07K2319/32 , A61K2300/00

摘要： Methods of inhibiting intimal hyperplasia in the vasculature of mammals, including primates, are disclosed. The methods comprise administering to the mammal an anti-PDGF receptor antibody, such as an anti-PDGF-alpha receptor antibody or an anti-PDGF-beta receptor antibody. The methods are useful in reducing intimal hyperplasia due to, for example, vascular injuries resulting from angioplasty, endarterectomy, reduction atherectomy or anastomosis of a vascular graft.

2.

发明授权
INHIBITION OF INTIMAL HYPERPLASIA USING ANTIBODIES TO PDGF RECEPTORS 失效
标题翻译：抗体PDGF受体素抑制内膜增生USE

公开(公告)号：EP0686044B1

公开(公告)日：1998-09-02

申请号：EP94909627.5

申请日：1994-02-17

申请人： ZymoGenetics, Inc. , THE UNIVERSITY OF WASHINGTON

发明人： HART, Charles E. , KENAGY, Richard D. , CLOWES, Alexander W.

IPC分类号： A61K39/395

CPC分类号： C07K16/2863 , A61K38/00 , A61K39/395 , C07K2317/24 , C07K2319/30 , C07K2319/32 , A61K2300/00

摘要： Methods of inhibiting intimal hyperplasia in the vasculature of mammals, including primates, are disclosed. The methods comprise administering to the mammal an anti-PDGF receptor antibody, such as an anti-PDGF-alpha receptor antibody or an anti-PDGF-beta receptor antibody. The methods are useful in reducing intimal hyperplasia due to, for example, vascular injuries resulting from angioplasty, endarterectomy, reduction atherectomy or anastomosis of a vascular graft.