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6 条记录 (耗时 0.011 秒)

    RECOMBINANT MICROORGANISM EXPRESSING AVERMECTIN ANALOGUE AND USE THEREOF
    1.
    发明公开
    RECOMBINANT MICROORGANISM EXPRESSING AVERMECTIN ANALOGUE AND USE THEREOF 有权
    AVEMECTIN-ANALOGON EXPRIMIERENDER REKOMBINANTER MIKROORGANISMUS UND DAVON VERWENDUNG

    公开(公告)号：EP3118305A1

    公开(公告)日：2017-01-18

    申请号：EP14885605.7

    申请日：2014-04-28

    申请人： Zhejiang Hisun Pharmaceutical Co. Ltd.

    发明人： HUANG, Jun ,  WANG, Jidong ,  CHEN, Anliang ,  DENG, Aiwen ,  LIN, Jiatan ,  YU, Zhen ,  LI, Meihong ,  LI, Na ,  WANG, Haibin ,  ZHENG, Linghui ,  BAI, Hua

    IPC分类号： C12N1/21 ,  C12R1/465 ,  C12N15/76 ,  C12P19/62

    CPC分类号： A01N43/90 ,  C12N15/76 ,  C12P19/623 ,  C12R1/465

    摘要： The present invention relates to a recombinant microorganism expressing avermectin or analogues thereof and construction method thereof, and also relates to a method of producing avermectin or analogues thereof using the recombinant microorganism, and avermectin or analogues thereof obtained using the method. In addition, the present invention further relates to uses of the avermectin or analogues thereof as insecticides. Using the recombinant microorganism of the present invention to produce avermectin or analogues thereof has numerous advantages, for example comprising at least one of the following: good stability, high yield, simple process, environmentally friendly, and greatly saving of production costs.

    摘要翻译： 本发明涉及表达除虫菌素或其类似物的重组微生物及其构建方法，还涉及使用该方法得到的重组微生物和除虫菌素或其类似物来生产除虫菌素或其类似物的方法。 此外，本发明还涉及除虫菌素或其类似物作为杀虫剂的用途。 使用本发明的重组微生物来生产除虫菌素或其类似物具有许多优点，例如包括以下至少一种：良好的稳定性，高产率，简单的工艺，环保且大大节省生产成本。

    A METHOD FOR THE SEPARATION AND PURIFICATION OF EPOTHILONES
    2.
    发明公开
    A METHOD FOR THE SEPARATION AND PURIFICATION OF EPOTHILONES 有权
    奥地利维吾尔族维也纳

    公开(公告)号：EP2241566A1

    公开(公告)日：2010-10-20

    申请号：EP08714810.2

    申请日：2008-02-01

    申请人： Zhejiang Hisun Pharmaceutical Co. Ltd.

    发明人： WANG, Jidong ,  ZHANG, Hui ,  WANG, Haibin ,  YING, Lingping ,  WANG, Sheng ,  GUAN, Xufang ,  BAI, Hua

    IPC分类号： C07D417/06

    CPC分类号： C07D417/06 ,  C07D493/04

    摘要： The invention discloses a method for the separation and purification of epothilones, especially discloses a method for the separation and purification of epothilones B and A using normal phase silica gel chromatography, which comprises loading the sample after dissolving the sample containing epothilones B and A with C 1 -C 7 alkyl halide compounds or mixing the sample with silica gel, then gradient eluting silica gel column by an elution solvent of normal phase silica gel column, and finally obtaining products.

    摘要翻译： 本发明公开了一种分离和纯化埃坡霉素的方法，特别公开了一种使用正相硅胶色谱分离和纯化埃坡霉素B和A的方法，该方法包括在将含有埃坡霉素B和A的样品溶解于C后加载样品 1〜7个卤代烷基化合物，或将样品与硅胶混合，然后用正相硅胶柱洗脱溶剂梯度洗脱硅胶柱，最后得到产物。