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公开(公告)号:EP2230299B1
公开(公告)日:2011-12-07
申请号:EP10168189.8
申请日:2003-01-21
申请人: ZymoGenetics, Inc.
发明人: Sprecher, Cindy A. , Kuijper, Joseph L. , Dasovich, Maria M. , Grant, Francis J. , Hammond, Angela K. , Gross, Jane A. , Dillon, Stacey R. , Kuestner, Rolf
IPC分类号: C12N5/10 , C12N15/19 , C12N15/62 , C12N15/63 , C07K14/52 , C07K16/24 , G01N33/53 , G01N33/567 , A61K38/19 , A61K39/395 , C07K14/54
CPC分类号: C07K16/24 , A01K2217/05 , A61K38/00 , C07K14/47 , C07K14/52 , C07K2317/24
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公开(公告)号:EP2230299A1
公开(公告)日:2010-09-22
申请号:EP10168189.8
申请日:2003-01-21
申请人: ZymoGenetics, Inc.
发明人: Sprecher, Cindy A. , Kuijper, Joseph L. , Dasovich, Maria M. , Grant, Francis J. , Hammond, Angela K. , Gross, Jane A. , Dillon, Stacey R. , Kuestner, Rolf
IPC分类号: C12N5/10 , C12N15/19 , C12N15/62 , C12N15/63 , C07K14/52 , C07K16/24 , G01N33/53 , G01N33/567 , A61K38/19 , A61K39/395 , C07K14/54
CPC分类号: C07K16/24 , A01K2217/05 , A61K38/00 , C07K14/47 , C07K14/52 , C07K2317/24
摘要: There is provided an antibody or antibody fragment which specifically binds to a portion of SEQ ID NO:2, wherein said portion consists of between 30 and 100 contiguous amino acids of SEQ ID NO:2, and wherein said portion contains amino acids selected from the group consisting of: (a) amino acid residues 54 to 59 of SEQ ID NO: 2; (b) amino acid residues 129 to 134 of SEQ ID NO: 2; (c) amino acid residues 53 to 58 of SEQ ID NO: 2; (d) amino acid residues 35 to 40 of SEQ ID NO: 2; (e) amino acid residues 33 to 38 of SEQ ID NO: 2; (f) amino acid residues 114 to 119 of SEQ ID NO: 2; (g) amino acid residues 101 to 105 of SEQ ID NO: 2; (h) amino acid residues 126 to 131 of SEQ ID NO: 2; (i) amino acid residues 113 to 118 of SEQ ID NO: 2; and (j) amino acid residues 158 to 162 of SEQ ID NO:2.
摘要翻译: 提供了与SEQ ID NO:2的一部分特异性结合的抗体或抗体片段,其中所述部分由SEQ ID NO:2的30-100个连续氨基酸组成,并且其中所述部分含有选自 组成:(a)SEQ ID NO:2的氨基酸残基54至59; (b)SEQ ID NO:2的氨基酸残基129至134; (c)SEQ ID NO:2的氨基酸残基53至58; (d)SEQ ID NO:2的氨基酸残基35至40; (e)SEQ ID NO:2的氨基酸残基33至38; (f)SEQ ID NO:2的氨基酸残基114至119; (g)SEQ ID NO:2的氨基酸残基101至105; (h)SEQ ID NO:2的氨基酸残基126至131; (i)SEQ ID NO:2的氨基酸残基113至118; 和(j)SEQ ID NO:2的氨基酸残基158至162。
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