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公开(公告)号：EP1137773B1
公开(公告)日：2008-08-13
申请号：EP99966032.7
申请日：1999-12-07
申请人： ZymoGenetics, Inc.
发明人： GAO, Zeren , HART, Charles, E. , PIDDINGTON, Christopher, S. , SHEPPARD, Paul, O. , SHOEMAKER, Kimberly, E. , GILBERTSON, Debra, G. , WEST, James, W.
IPC分类号： C12N15/12 , C12N15/11 , C12N5/10 , C12N15/62 , C07K14/52 , C07K16/22 , G01N33/68 , C12Q1/68 , A61K38/18
CPC分类号： C07K14/475 , A61K38/00 , C07K14/52
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公开(公告)号：EP1185645A1
公开(公告)日：2002-03-13
申请号：EP00936252.6
申请日：2000-05-23
申请人： ZymoGenetics, Inc.
CPC分类号： C07K14/47 , A61K38/00 , C07K2319/00 , C12N2799/026
摘要： The present invention relates to polynucleotide and polypeptide molecules for zacrp7, a novel member of the family of proteins bearing a collagen-like domain and a C1q domain. The polypeptides and polynucleotides encoding them, are involved in homo and heterotrimerization or oligomerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp7 polypeptides.
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公开(公告)号：EP1185643A1
公开(公告)日：2002-03-13
申请号：EP00930799.2
申请日：2000-05-18
申请人： ZymoGenetics, Inc.
CPC分类号： C07K14/47 , A61K38/00 , C07K2319/00 , C12N2799/026
摘要： The present invention relates to polynucleotide and polypeptide molecules for zacrp5, a novel member of the family of proteins bearing a collagen-like domain and a C1q domain. The polypeptides and polynucleotides encoding them, are involved in trimerization and be used in the study thereof. The present invention also includes antibodies to the zacrp5 polypeptides.
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公开(公告)号：EP1171599A1
公开(公告)日：2002-01-16
申请号：EP00926104.1
申请日：2000-04-19
申请人： ZymoGenetics, Inc.
CPC分类号： C07K14/47 , A61K38/00 , C07K2319/00 , C12N2799/026
摘要： The present invention relates to polynucleotide and polypeptide molecules for zacrp2, a novel member of the family of proteins bearing a collagen-like domain and a Clq domain. The polypeptides and polynucleotides encoding them, are involved in dimerization or oligomerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp2 polypeptides.
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公开(公告)号：EP1562967A2
公开(公告)日：2005-08-17
申请号：EP03726445.4
申请日：2003-04-25
申请人： ZymoGenetics, Inc.
CPC分类号： C07K14/472
摘要： Novel zacrp14 polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. Also disclosed are antibodies to the zacrp14 protein or fragments thereof.
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公开(公告)号：EP1504027A2
公开(公告)日：2005-02-09
申请号：EP03747338.6
申请日：2003-04-25
申请人： ZymoGenetics, Inc.
IPC分类号： C07K14/435 , A61K39/00 , A61K39/395 , C07H21/04 , C12N15/63 , C12N5/06 , C12N15/09
CPC分类号： C07K14/4702 , A61K38/00 , C07K2319/30
摘要： Novel zacrp8 polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods of using are disclosed. Also disclosed are antibodies to the zacrp8 protein or fragments thereof.
摘要翻译： 公开了新的zacrp8多肽，编码该多肽的多核苷酸，以及相关的组合物和使用方法。 还公开了针对zacrp8蛋白或其片段的抗体。
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公开(公告)号：EP1137773A2
公开(公告)日：2001-10-04
申请号：EP99966032.7
申请日：1999-12-07
申请人： ZymoGenetics, Inc.
发明人： GAO, Zeren , HART, Charles, E. , PIDDINGTON, Christopher, S. , SHEPPARD, Paul, O. , SHOEMAKER, Kimberly, E. , GILBERTSON, Debra, G. , WEST, James, W.
IPC分类号： C12N15/12 , C12N15/11 , C12N5/10 , C12N15/62 , C07K14/52 , C07K16/22 , G01N33/68 , C12Q1/68 , A61K38/18
CPC分类号： C07K14/475 , A61K38/00 , C07K14/52
摘要： Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprises an amino acid segment that is at least 90% identical to residues 46-163 of SEQ ID NO:2 or residues 235-345 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.
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公开(公告)号：EP1181369B1
公开(公告)日：2008-02-13
申请号：EP00942653.7
申请日：2000-06-01
申请人： ZymoGenetics, Inc.
IPC分类号： C12N15/19 , C07K14/52 , C12Q1/68 , C07K16/24 , C12N15/62 , A61K38/19 , C12N5/10 , C12N1/21 , C12N1/19 , G01N33/68 , C12N5/06
CPC分类号： C07K14/52 , A61K38/00 , C07K2319/00 , C07K2319/02 , C12N2799/026
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公开(公告)号：EP1181369A1
公开(公告)日：2002-02-27
申请号：EP00942653.7
申请日：2000-06-01
申请人： ZymoGenetics, Inc.
IPC分类号： C12N15/19 , C07K14/52 , C12Q1/68 , C07K16/24 , C12N15/62 , A61K38/19 , C12N5/10 , C12N1/21 , C12N1/19 , G01N33/68 , C12N5/06
CPC分类号： C07K14/52 , A61K38/00 , C07K2319/00 , C07K2319/02 , C12N2799/026
摘要： This present invention is directed to polypeptide and polynucleotide molecules that encode a four-helical bundle cytokine. The cytokine has been designated zsig81, and has restricted expression in primarily heart, lung and liver. zsig81 has been shown to stimulate proliferation of hematopoietic cells and will be useful expansion of these cells, as well as conditions associated with hematopoietic cells. The invention is directed to antibodies and methods of making zsig81 polypeptides, as well.
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公开(公告)号：EP1173565A1
公开(公告)日：2002-01-23
申请号：EP00926106.6
申请日：2000-04-19
申请人： ZymoGenetics, Inc.
CPC分类号： C07K14/47 , A61K38/00 , C07K2319/00 , C12N2799/026
摘要： The present invention relates to polynucleotide and polypeptide molecules for zacrp3, a novel member of the family of proteins bearing a collagen-like domain and a C1q domain. The polypeptides and polynucleotides encoding them, are involved in dimerization or oligomerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp3 polypeptides.
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