公开(公告)号：EP3679343B1

公开(公告)日：2023-06-07

申请号：EP18854929.9

申请日：2018-09-04

发明人： LATOUR, Robert A. ,  CHUMANOV, George ,  CHOLEWCZYNSKI, Alexandra

IPC分类号： G01N1/38 ,  G01N1/40 ,  G01N21/25 ,  G01N21/29 ,  G01N21/78 ,  G01N33/62 ,  G01N33/493

公开(公告)号：EP3482401B1

公开(公告)日：2021-03-10

申请号：EP17824890.2

申请日：2017-07-06

发明人： ZHENG, Xiao, Ran ,  TAKACS, Endre ,  LEISING, Mark

IPC分类号： G21K1/02 ,  A61B6/02 ,  A61N5/00 ,  A61N5/01

公开(公告)号：EP3298086B1

公开(公告)日：2020-09-09

申请号：EP16800517.1

申请日：2016-05-19

申请人： Clemson University Research Foundation

发明人： MOUNT, Andrew S. ,  CHAN, Bin San ,  JOHNSTONE, Mary Beth

IPC分类号： C09D5/16 ,  A01P9/00 ,  C07K7/08 ,  A61K38/04

公开(公告)号：EP3679343A1

公开(公告)日：2020-07-15

申请号：EP18854929.9

申请日：2018-09-04

申请人： Clemson University Research Foundation

发明人： LATOUR, Robert A. ,  CHUMANOV, George ,  CHOLEWCZYNSKI, Alexandra

IPC分类号： G01N1/38 ,  G01N1/40 ,  G01N21/25 ,  G01N21/29 ,  G01N21/78 ,  G01N33/62

公开(公告)号：EP3463818A1

公开(公告)日：2019-04-10

申请号：EP17803415.3

申请日：2017-05-23

申请人： University of South Carolina ,  Clemson University Research Foundation ,  Tighitco, Inc.

发明人： DE BACKER, Wout ,  BERGS, Arturs Peteris ,  VAN TOOREN, Michael Johannes Leonardus ,  LUZINOV, Igor ,  BORODINOV, Nikolay

IPC分类号： B29C67/00 ,  B29C67/24 ,  B29C69/00

公开(公告)号：EP3347062A1

公开(公告)日：2018-07-18

申请号：EP16845016.1

申请日：2016-09-08

申请人： Clemson University

发明人： MCGUIRE, Rachel ,  BOREM, Ryan ,  MERCURI, Jeremy

IPC分类号： A61L27/24 ,  A61L27/40 ,  A61L27/50 ,  A61F2/44

CPC分类号： A61L27/3633 ,  A61F2/08 ,  A61F2/44 ,  A61F2/442 ,  A61F2002/4435 ,  A61L27/3604 ,  A61L27/3654 ,  A61L27/3658 ,  A61L27/3662 ,  A61L27/3683 ,  A61L27/50 ,  A61L27/52 ,  A61L2430/06 ,  A61L2430/10 ,  A61L2430/38

摘要： Biocompatible biomimetic materials that exhibit desirable mechanical properties while also encouraging cell ingrowth and proliferation are described. The biomaterials include a multi-layer laminate of three or more decellularized aligned collagen tissues. The individual layers are aligned with one another in an angle-ply arrangement, with the collagen of each layer aligned at an angle to the collagen of the adjacent layer. The biomaterials are useful as collagenous graft materials such as a patch for a hernia in an annulus fibrosus or grafting materials for repair of tendons, ligaments, cartilage and other musculoskeletal tissues.

公开(公告)号：EP2460525B8

公开(公告)日：2016-09-14

申请号：EP11181250.9

申请日：2006-04-07

申请人： CURF Clemson University Research Foundation

发明人： Vyavahare, Narendra R. ,  Isenburg, Jason C. ,  Simionescu, Dan T.

IPC分类号： A61K31/7024 ,  A61F2/00 ,  A61P9/14

CPC分类号： A61K31/7024

公开(公告)号：EP1874223B1

公开(公告)日：2013-08-07

申请号：EP06758289.0

申请日：2006-04-07

申请人： Clemson University Research Foundation (CURF)

发明人： VYAVAHARE, Narendra, R. ,  ISENBURG, Jason, C. ,  SIMIONESCU, Dan, T.

IPC分类号： A61K31/7024 ,  A61F2/00 ,  A61P9/14

CPC分类号： A61K31/7024

公开(公告)号：EP1878777A2

公开(公告)日：2008-01-16

申请号：EP07119977.2

申请日：2002-02-14

申请人： Clemson University

发明人： Jarvis, Christine W. ,  Bennett, Robert E. ,  Frederick, Brian

IPC分类号： C09J5/06 ,  C09J5/10

CPC分类号： B29C65/5071 ,  B29C65/04 ,  B29C65/08 ,  B29C65/16 ,  B29C65/18 ,  B29C65/4815 ,  B29C65/5021 ,  B29C65/5085 ,  B29C65/8215 ,  B29C65/8253 ,  B29C66/1122 ,  B29C66/43 ,  B29C66/435 ,  B29C66/71 ,  B29C66/712 ,  B29C66/729 ,  B29C66/73115 ,  B29C66/73116 ,  B29C66/83413 ,  B29C66/91411 ,  B29C66/919 ,  B29C66/91931 ,  B29C66/91933 ,  B29C66/91935 ,  B29C66/929 ,  B29K2007/00 ,  B29K2021/00 ,  B29K2021/003 ,  B29K2101/12 ,  B29K2105/0836 ,  B29K2105/0845 ,  B29K2105/0854 ,  B29K2311/10 ,  B29K2313/00 ,  B29K2711/12 ,  C09J5/10 ,  Y10T156/1003 ,  Y10T156/1051 ,  Y10T428/19 ,  Y10T428/192 ,  Y10T428/2419 ,  Y10T428/24959 ,  B29K2077/00 ,  B29K2075/00 ,  B29K2067/00 ,  B29K2023/22 ,  B29K2023/12 ,  B29K2023/06

摘要： A method for joining two or more substrates with a seam is provided. The seam is formed with a thermoplastic tape that is capable of forming an adhesive bond and a physical bond with a substrate. For instance, in one embodiment, the thermoplastic tape is formed from a polyurethane film. In addition, the seam can be utilized in a flat configuration or folded into a variety of different shapes, such as in a z-shaped configuration. As a result of the present invention, it has been discovered that a seam can be formed to have improved strength without substantially sacrificing the desired functional properties of the substrate materials.

摘要翻译： 提供了一种用于接合具有接缝的两个或更多个衬底的方法。 接缝形成有热塑性带确实能够在粘合剂粘结和与基板的物理键形成的。 例如，在一个实施方案中，热塑性带从聚氨酯电影形成。 此外，接缝可以在平坦的构造被利用或折叠成各种不同的形状，颜色的：如在Z形结构。 作为本发明的结果，已经发现没有一个接缝可被形成为具有改善的强度，而不会牺牲基本上与基板材料的所需功能特性。

公开(公告)号：EP1444058A1

公开(公告)日：2004-08-11

申请号：EP02770612.6

申请日：2002-10-18

申请人： Clemson University

发明人： GREENE, Annel, K.

IPC分类号： B09B3/00 ,  C12N1/00 ,  C12N1/14 ,  C12N1/16 ,  C12N1/18 ,  C12N1/20 ,  C12P1/00 ,  C12P1/02 ,  C12P1/06 ,  C12P7/00 ,  C12P7/02 ,  C12P7/06 ,  C12P7/08 ,  C12P7/14

CPC分类号： C12P7/08 ,  C12P1/00 ,  Y02E50/343

摘要： A process for converting organic waste materials into useable products and products thereof is disclosed. According to the process, organic waste materials are contacted with ozone thereby converting said waste material to a substrate or medium. The substrate is a product of the process and it may be further contacted with organisms for bioconversion to further products. The organisms can include bacteria, yeast, fungi, plant cells, animal cells and genetically engineered organisms which are selected for their ability to bioconvert the substrate and produce a selected product.