专利检索 caee:"Pharmacia Corporation,Corporate Patent Department" 第 1 页

1.

发明公开
2-AMINO-2-ALKYL-3 HEXENOIC AND HEXYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS 审中-公开
标题翻译： 2-氨基-2-烷基-3-HEXENSÄURE-HEXYNSÄUREDERIVATE和作为抑制剂一氧化氮合酶

公开(公告)号：EP1317420A1

公开(公告)日：2003-06-11

申请号：EP01970857.7

申请日：2001-09-15

申请人： Pharmacia Corporation,Corporate Patent Department

发明人： HANSEN, Donald, Jr. , WEBBER, Ronald, Keith , PITZELE, Barnett, S. , AWASTHI, Alok, K.

IPC分类号： C07C257/14 , C07C271/22 , C07C255/30 , C07C229/30

CPC分类号： C07C255/30 , C07B2200/07 , C07B2200/09 , C07C229/30 , C07C257/14 , C07C271/22

摘要： The present invention relates to 2-amino-2-alkyl-3 hexenoic and hexynoic acid derivatives and their use in therapy, in particular their use as nitric oxide synthase inhibitors.

2.

发明公开
Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation 审中-公开
标题翻译：荧光增白剂BENZENSULFONYL-DERIVATE ZUR BEHANDLUNG VONENTZÜNDUNGEN

公开(公告)号：EP1251126A2

公开(公告)日：2002-10-23

申请号：EP02008273.1

申请日：2002-04-19

申请人： Pharmacia Corporation, Corporate Patent Department

发明人： Brown, David L. , Graneto, Matthew J. , Ludwig, Cindy L. , Molyneaux, John M. , Talley, John J.

IPC分类号： C07D231/12 , C07D401/04 , C07D261/08 , C07D413/04

CPC分类号： C07D231/12 , C07D261/08 , C07D307/32

摘要： Methods of treating cyclooxygenase-2 mediated disorders comprising administering to a subject a therapeutically effective amount of one or more fluoro-substituted benzenesulfonyl compounds corresponding to Formula I:
wherein A, X, n, R 1 , R 2 , and R 3 are as described in the specification, and novel fluoro-substituted benzenesulfonyl compounds within Formula I.

摘要翻译： 治疗环加氧酶-2介导的病症的方法包括向受试者施用治疗有效量的对应于式I的一种或多种氟取代的苯磺酰基化合物：其中A，X，n，R 1，R 2，和R 3如说明书中所述，以及式I中的新的氟取代的苯磺酰基化合物。

3.

发明公开
Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation 审中-公开
标题翻译： FLUOR-取代苯衍生物对炎症的治疗

公开(公告)号：EP1251126A3

公开(公告)日：2002-10-30

申请号：EP02008273.1

申请日：2002-04-19

申请人： Pharmacia Corporation, Corporate Patent Department

发明人： Brown, David L. , Graneto, Matthew J. , Ludwig, Cindy L. , Molyneaux, John M. , Talley, John J.

IPC分类号： C07D231/12 , C07D401/04 , C07D261/08 , C07D413/04

CPC分类号： C07D231/12 , C07D261/08 , C07D307/32

摘要： Methods of treating cyclooxygenase-2 mediated disorders comprising administering to a subject a therapeutically effective amount of one or more fluoro-substituted benzenesulfonyl compounds corresponding to Formula I: wherein A, X, n, R 1 , R 2 , and R 3 are as described in the specification, and novel fluoro-substituted benzenesulfonyl compounds within Formula I.