摘要:
A hemostatic valve unit having a splittable housing. The hemostatic valve comprising housing parts radially movable when said housing is split. Said hemostatic valve comprising a through port with proximal and distal openings configured to provide a communication channel for delivery of a medical device to and/or from the interior of a heart.
摘要:
A device (30) for modifying conduction, electrical connection and propagation properties in a tissue comprising :a structural platform (30) made of a biocompatible material; the platform (30) conformable to a shape of a target tissue site (36) having a vessel wall; the platform (30) having a treatment component sized and shaped to induce a fibrotic response in the target tissue (36); and the treatment component being configured to cause sufficient fibrotic response so as to substantially eliminate the cardiac arrhythmias, wherein the device is configured to be radially expanded to overstretch the vessel wall so that the overstretching induce fibrosis in the tissue at the target tissue site (36).
摘要:
A tissue cutting device is disclosed, which is structured and arranged to be inserted through the vascular system into a body vessel adjacent to the heart and/or into the heart, and to be subsequently subjected to a change of shape in order to penetrate into the heart tissue. The device comprises at least one connection element that is arranged such that a connection formed from said connection element between a first and second part of said tissue cutting device is configured to break when said connection element is subjected to a specific external influence. The tissue cutting device may thus be used for controllably treating disorders to the heart rhythm regulation system. A kit of devices provides a plurality of devices for creating a lesion pattern for treating such disorders.
摘要:
A device (30) for modifying conduction, electrical connection and propagation properties in a tissue comprising :a structural platform (30) made of a biocompatible material; the platform (30) conformable to a shape of a target tissue site (36) having a vessel wall; the platform (30) having a treatment component sized and shaped to induce a fibrotic response in the target tissue (36); and the treatment component being configured to cause sufficient fibrotic response so as to substantially eliminate the cardiac arrhythmias, wherein the device is configured to be radially expanded to overstretch the vessel wall so that the overstretching induce fibrosis in the tissue at the target tissue site (36).
摘要:
A tissue cutting device is disclosed, comprising a tubular part, that is structured and arranged to be inserted in a temporary delivery shape through a vascular system into a body vessel, and to be subsequently subjected to a change of shape, from said temporary delivery shape via an expanded delivered shape to a further expanded shape, extending at least beyond an outer surface of said body vessel in order to create a cutting action configured for cutting said body vessel, wherein said tissue cutting device is structured and arranged to penetrate a wall of said body vessel by said cutting action, in such a manner that a cut of said tissue created by said cutting action is continuously replaced by scar tissue, wherein the tubular part of said device comprises a plurality of segments connected to each other in longitudinal direction of said tubular part of said device, wherein a first segment of said plurality of segments has a dimension in a direction perpendicular to said longitudinal direction of said tubular part of said device that is larger than that dimension of a second segment thereof, at least in said expanded delivered shape.
摘要:
The present invention generally relates to the use of small particles, such as micro particles or nanoparticles, to produce a therapeutic scar such as 'trans-mural' scarring or other desired 'deep tissue' scarring. In one preferred embodiment, these particles can be delivered to a target location by an implant. More specifically, these particles can be incorporated into the structure of implants or into the coatings on implants. In another preferred embodiment, these small particles can be delivered directly with a catheter by electrophoresis or hydraulic pressure.
摘要:
The present invention seeks to provide an implant configured to utilize at least two different scar-generating mechanisms that are generated in sequential or overlapping stages. For example, in one embodiment the present invention provides an expandable device that can be positioned at a desired target location within a patient to generate mechanical ablation damage. After a predetermined amount of mechanical ablation has occurred, additional ablation damage is generated by a different source, such as energy delivery, drug delivery, or inflammatory material delivery. In this respect, the overall ablation scarring can be better controlled by utilizing the ablation techniques that are most appropriate at specific phases of a technique or locations within a patient.
摘要:
A hemostatic valve unit having a splittable housing. The hemostatic valve comprising housing parts radially movable when said housing is split. Said hemostatic valve comprising a through port with proximal and distal openings configured to provide a communication channel for delivery of a medical device to and/or from the interior of a heart.