摘要:
The present invention relates to indolone derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
摘要:
The present invention relates to a new process for preparing 2-oxo-1-pyrrolidine derivatives of general formula (I), comprising the cyclisation of an intermediate of general formula (II) wherein the substituents are as defined in the specification.
摘要:
A removable, plasticizer resistant pressure sensitive composition that is particularly useful for PSA applications on plasticizer containing vinyl films is provided. The pressure sensitive adhesive comprises: (a) at least one hydrophobic monomer; (b) about 0.2 to about 10 wt. % of at least one hydrophilic monomer; (c) about 1 to about 40 wt. % of one partially hydrophilic monomer (d) an effective amount of a crosslinker selected from diallyl maleate or a compound represented by the formula: wherein R is selected from hydrogen, methyl, or ethyl, and R' is selected from vinyl, allyl, or methallyl; wherein the pressure sensitive adhesive does not contain a plasticizer.
摘要:
There is described an optionally flexible and/or polymeric packaging film (e.g. BOPP) having at least one tear line (5) and at least one tab (7) thereon, where the tab (7) has a free end, an end attached to the film and free sides connecting the two ends, the tab (7) positioned so the axis of at least one tear line (5) passes through both ends of the tab (7) characterised in that: (a) at least one of the free sides of the tab (7) taper outwardly from the attached end and the tear line (5); and (b) at least one angle theta (theta) is an acute angle greater than about 5° where theta (theta) is defined as an angle subtending the free end of the tab (7) measured between: (i) an axis defined by the average direction of one of the tab (7) sides averaged over a the last quarter of the maximum length of the tab (7) starting from the attached end; and (ii) an axis defined by the average direction of the tear line (5) along the film. A method of preparing such films and packaging articles (such as cigarette cartons) over-wrapped with such films are also described.
摘要:
There is described a label comprising a self supporting sheet of a biopolymer, preferably cellulose (e.g. regenerated cellulose, cellulose acetate and/or PLA), said sheet being substantially transparent to visible light when uncoated, wherein said sheet comprises: (a) a first coating on at least one surface thereof to aid printability thereon; (b) a second coating comprising an adhesive dispersible in an aqueous medium; and (c) optionally a third coating to modify water permeability through the sheet. The labels are to be applied to articles such as glass containers. Preferred labels are wet glue cellulose labels, for example where the first coating also comprises a copolymer of vinyl chloride and vinyl acetate to aid water permeability and hence rapid drying of the label on an article.
摘要:
There is described a multi-layer oriented polyolefin film suitable for receiving a metal layer to form a high barrier thereon the film comprising a coat polymer layer at one surface, a metallisable polymer layer at the opposite surface and a core polymer layer sandwiched between and separating the coat layer and the metallisable layer characterised in that (a) the metallisable layer comprises at least one metallocene polypropylene (mPP); and/or (b) the core layer comprises at least 2% by weight (preferably at least 10%) of a hard resin preferably selected from at least one of: a dicyclopentadiene (DCPD) resin; a propylene-butylene copolymer and/or a hydrocarbon resin obtainable from C5 and/or C9 monomer(s).Preferably the film of the invention is metallised on at least one outer surface, more preferably directly onto the metallisable layer containing mPP.
摘要:
The present invention relates to a process wherein a cyclic carbonate compound bearing an electrophilic group is reacted with a compound containing a nucleophilic group, especially an amine group. Such reactions permit to obtain urethane groups useful in polymer preparation, such as polyurethanes, or other urethane-containing polymers.
摘要:
Disclosed is a copolyester resin having number average molecular weight over 5,000 for solventborne metal coating binder, which has superior gloss retention and color stability after long term outdoor exposure, and a coating composition comprising the same. The copolyester has excellent weatherability and color stability. The copolyester resin is prepared through the polycondensation of an acid component comprising 60-90 mol% of aromatic dicarboxylic acid selected from the group consisting of isophthalic acid, C1-C2 alkylester of isophthalic acid, phthalic acid, C1-C2 alkylester of phthalic acid, phthalic anhydride, and mixtures thereof, and 10-40 mol% of cycloaliphatic dicarboxylic acid selected from the group consisting of 1,2-cyclohexane dicarboxylic anhydride, 1,2-cyclohexane dicarboxylic acid, C1-C2 alkylester of 1,2-cyclohexane dicarboxylic acid, 1,4-cyclohexane dicarboxylic acid, C1-C2 alkylester of 1,4-cyclohexane dicarboxylic acid, and mixtures thereof, an alcohol component comprising 60-100 mol% of 2,2-dialkyl-1,3-propandiol and 0-40 mol% of a polyvalent alcohol and 0-5 mol% of a polyvalent alcohol or acid.
摘要:
A compound selected from the (4R) and (4S) diastereoisomers of (2S)-2-[2-oxo-4-propylpyrrolidinyl]butanamide or a pharmaceutically acceptable salt thereof. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
摘要:
There is described a process for labeling an article and/or document for authentication purposes. The article or document (such as BOPP and/or cellulose film) incorporates therein particles having a taggant bound to the surface thereof. The preferred taggant is a DNA strand of at least eight (preferably 25) base pairs long attached to inorganic particles by the addition reaction between an acrylate group and a polar group such as amino or hydroxy. Alternatively silica particles can be modified by reacting first with aminopropyltriethoxy silane and then a reagent selected from: a diacid with a polyethylene glycol spacer group (e.g. polyethylene glycol dicarboxymethyl) succinic anhydride; and/or a diisothiocyanate (e.g. 1,4-phenylene diisothiocyanate (PDITC)) to form functional silica particles capable of reacting directly with a terminal amide and/or hydroxy group of an oligonucleotide such as DNA. The tagged particles can be detected by use of a fluorescent probe which hybridises with the DNA sequence selected tag the article or document.