公开(公告)号：EP3391929A1

公开(公告)日：2018-10-24

申请号：EP18176009.1

申请日：2013-04-09

申请人： Wolfe, Thomas J.

发明人： Wolfe, Thomas J.

IPC分类号： A61M25/06 ,  A61M25/09 ,  A61B17/22 ,  A61B18/00 ,  A61N1/40 ,  A61N2/02 ,  A61M25/01 ,  A61M25/00 ,  A61B17/00 ,  A61B18/04

CPC分类号： A61N1/40 ,  A61B17/22 ,  A61B18/04 ,  A61B2017/00876 ,  A61B2017/22038 ,  A61B2017/22042 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61M25/00 ,  A61M25/0054 ,  A61M25/0082 ,  A61M25/0108 ,  A61M25/0158 ,  A61M25/09 ,  A61M2025/0008 ,  A61M2025/09133 ,  A61M2025/09183 ,  A61N2/02

摘要： A method of treating a pathologic lesion, such as an intravascular thrombus, is disclosed. The method comprises providing a guide wire and catheter with at least one inductive element within a blood vessel to a distal location associates with the pathologic lesion; and providing electromagnetic energy via at least one inductive element to the pathologic lesion to cause thrombolysis. Medicated magnetic particles can be endovascularly localized and concentrated to the vascular territory affected by the pathologic lesion. A shaping device, comprising a flexible segment for encompassing the distal end of a guide wire or catheter; a handle coupled to the flexible segment; and
surface markings to allow measurements from a terminal portion of the guide wire. A catheter, comprising: a hollow tube for insertion into a hollow organ or blood vessel;
a guide wire; and a first inductive element disposed on a distal end of the guide wire, the first inductive element receiving an electric current and having a diameter of less than 0.105 inches. A catheter comprising: a guide wire having a radius less than 0.0525 inches; and a coil means for providing electromagnetic energy, the coil means comprised of at least one conductive wire disposed on a distal end of the guide wire, the coil means having a diameter of less than 0.105 inches, the conductive wire having a diameter of less than 0.050 inches.

公开(公告)号：EP2836267B1

公开(公告)日：2018-06-06

申请号：EP13775265.5

申请日：2013-04-09

申请人： Wolfe, Thomas J.

发明人： Wolfe, Thomas J.

IPC分类号： A61M25/06 ,  A61M25/09 ,  A61B17/22 ,  A61B18/00 ,  A61N1/40 ,  A61N2/02 ,  A61M25/01 ,  A61M25/00 ,  A61B17/00 ,  A61B18/04

CPC分类号： A61N1/40 ,  A61B17/22 ,  A61B18/04 ,  A61B2017/00876 ,  A61B2017/22038 ,  A61B2017/22042 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61M25/00 ,  A61M25/0054 ,  A61M25/0082 ,  A61M25/0108 ,  A61M25/0158 ,  A61M25/09 ,  A61M2025/0008 ,  A61M2025/09133 ,  A61M2025/09183 ,  A61N2/02

摘要： A method of treating a pathologic legion, such as an intravascular thrombus, is disclosed. The method comprises providing a guide wire and catheter with at least one inductive element within a blood vessel to a distal location associated with the pathologic lesion; and providing electromagnetic energy via at least one inductive element to the pathologic lesion to cause thrombolysis. Medicated magnetic particles can be endovascularly localized and concentrated to the vascular territory affected by the pathologic lesion.

公开(公告)号：EP2836267A4

公开(公告)日：2015-12-23

申请号：EP13775265

申请日：2013-04-09

申请人： WOLFE THOMAS J

发明人： WOLFE THOMAS J

IPC分类号： A61M25/06 ,  A61B17/00 ,  A61B17/22 ,  A61B18/00 ,  A61B18/04 ,  A61M25/00 ,  A61M25/01 ,  A61M25/09 ,  A61N1/40 ,  A61N2/02

CPC分类号： A61N1/40 ,  A61B17/22 ,  A61B18/04 ,  A61B2017/00876 ,  A61B2017/22038 ,  A61B2017/22042 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61M25/00 ,  A61M25/0054 ,  A61M25/0082 ,  A61M25/0108 ,  A61M25/0158 ,  A61M25/09 ,  A61M2025/0008 ,  A61M2025/09133 ,  A61M2025/09183 ,  A61N2/02

摘要： A method of treating a pathologic legion, such as an intravascular thrombus, is disclosed. The method comprises providing a guide wire and catheter with at least one inductive element within a blood vessel to a distal location associated with the pathologic lesion; and providing electromagnetic energy via at least one inductive element to the pathologic lesion to cause thrombolysis. Medicated magnetic particles can be endovascularly localized and concentrated to the vascular territory affected by the pathologic lesion.

公开(公告)号：EP2836267A1

公开(公告)日：2015-02-18

申请号：EP13775265.5

申请日：2013-04-09

申请人： Wolfe, Thomas J.

发明人： Wolfe, Thomas J.

IPC分类号： A61M25/06 ,  A61M25/09 ,  A61B17/22 ,  A61B18/00

CPC分类号： A61N1/40 ,  A61B17/22 ,  A61B18/04 ,  A61B2017/00876 ,  A61B2017/22038 ,  A61B2017/22042 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61M25/00 ,  A61M25/0054 ,  A61M25/0082 ,  A61M25/0108 ,  A61M25/0158 ,  A61M25/09 ,  A61M2025/0008 ,  A61M2025/09133 ,  A61M2025/09183 ,  A61N2/02

摘要： A method of treating a pathologic legion, such as an intravascular thrombus, is disclosed. The method comprises providing a guide wire and catheter with at least one inductive element within a blood vessel to a distal location associated with the pathologic lesion; and providing electromagnetic energy via at least one inductive element to the pathologic lesion to cause thrombolysis. Medicated magnetic particles can be endovascularly localized and concentrated to the vascular territory affected by the pathologic lesion.

摘要翻译： 公开了一种治疗病态军团例如血管内血栓的方法。 该方法包括提供具有血管内的至少一个感应元件的导丝和导管至与病理损伤相关联的远端位置; 并且通过至少一个感应元件向病理损伤提供电磁能以引起溶栓。 药物磁性颗粒可以被血管内局部化并浓缩至受病理损伤影响的血管区域。

公开(公告)号：EP2490764A4

公开(公告)日：2013-04-10

申请号：EP10825609

申请日：2010-10-20

申请人： WOLFE THOMAS J

发明人： WOLFE THOMAS J

IPC分类号： A61N2/10 ,  A61B17/20 ,  A61M25/00

CPC分类号： A61N1/40 ,  A61B17/22 ,  A61B2017/00876 ,  A61B2017/22038 ,  A61B2017/22042 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61M25/00 ,  A61M25/0054 ,  A61M25/0082 ,  A61M25/0108 ,  A61M25/0158 ,  A61M25/09 ,  A61M2025/0008 ,  A61M2025/09133 ,  A61M2025/09183 ,  A61N2/02

公开(公告)号：EP2490764B1

公开(公告)日：2014-09-10

申请号：EP10825609.0

申请日：2010-10-20

申请人： Wolfe, Thomas J.

发明人： Wolfe, Thomas J.

IPC分类号： A61N2/10 ,  A61B17/20 ,  A61M25/00

CPC分类号： A61N1/40 ,  A61B17/22 ,  A61B2017/00876 ,  A61B2017/22038 ,  A61B2017/22042 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61M25/00 ,  A61M25/0054 ,  A61M25/0082 ,  A61M25/0108 ,  A61M25/0158 ,  A61M25/09 ,  A61M2025/0008 ,  A61M2025/09133 ,  A61M2025/09183 ,  A61N2/02

公开(公告)号：EP2490764A2

公开(公告)日：2012-08-29

申请号：EP10825609.0

申请日：2010-10-20

申请人： Wolfe, Thomas J.

发明人： Wolfe, Thomas J.

IPC分类号： A61N2/10 ,  A61B17/20 ,  A61M25/00

CPC分类号： A61N1/40 ,  A61B17/22 ,  A61B2017/00876 ,  A61B2017/22038 ,  A61B2017/22042 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61M25/00 ,  A61M25/0054 ,  A61M25/0082 ,  A61M25/0108 ,  A61M25/0158 ,  A61M25/09 ,  A61M2025/0008 ,  A61M2025/09133 ,  A61M2025/09183 ,  A61N2/02

摘要： A method of treating an intravascular thrombus is disclosed. The method comprises providing a guide wire and catheter with at least one inductive element within a blood vessel to a distal location associated with the thrombus; and providing electromagnetic energy via at least one inductive element to the thrombus to cause thrombolysis. Medicated magnetic particles can be endovascularly localized and concentrated to the vascular territory affected by thrombosis. The method can also include providing an actuated segment on the distal portion of the guide wire to impart mechanical energy at the site of distal thrombus to work adjunctively with the inductive element facilitating thrombolysis. The guide wire can be shaped using an external guide wire shaping method to enable the user to impart precisely defined complex shapes to the distal aspect of the guide wire. The method can also include providing a support mechanism for the catheter using an actuator segment incorporated into or onto the catheter to aid in the proximal support for far distal localization of the guide wire mounted induction element and actuator.