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公开(公告)号：EP3425391A1
公开(公告)日：2019-01-09
申请号：EP18175398.9
申请日：2012-11-05
申请人： inRegen
IPC分类号： G01N33/50
摘要： The present invention concerns bioactive renal cell populations, in particular a B2 cell population comprising an enriched population of tubular cells and wherein the renal cell population is depleted of a B1 cell population, renal cell constructs, and methods of screening tests agents using the bioactive renal cell populations.
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公开(公告)号：EP2912165B1
公开(公告)日：2019-06-19
申请号：EP13786132.4
申请日：2013-10-24
申请人： inRegen
发明人： BASU, Joydeep , GUTHRIE, Kelly , JUSTEWICZ, Dominic , BURNETTE, Teresa , BRUCE, Andrew , KELLEY, Russell, W. , LUDLOW, John, W.
IPC分类号： C12N5/071
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公开(公告)号：EP3388509A1
公开(公告)日：2018-10-17
申请号：EP18160803.5
申请日：2009-11-12
申请人： inRegen
发明人： PRESNELL, Sharon , BRUCE, Andrew , WALLACE, Shay, M , CHOUDHURY, Sumana , KELLEY, Russell, W , JAYO, Manuel, J , WERDIN, Eric, S , TATSUMI, Patricia, D , REINSCH, Jessica, J , BERTRAM, Timothy, A , KNIGHT, Oluwatoyin, A , RAPOPORT, Scott, H , ILAGAN, Roger, M
CPC分类号： A61K35/22 , A61K35/12 , C12N5/0686 , C12N2500/02
摘要： The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
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公开(公告)号：EP2773955B1
公开(公告)日：2018-07-18
申请号：EP12787307.3
申请日：2012-11-05
申请人： inRegen
CPC分类号： G01N33/5082 , C12N5/0686 , C12N2500/02 , C12N2503/02 , C12Q1/32 , G01N33/4833 , G01N33/5008 , G01N33/5014 , G01N33/5023 , G01N33/5044 , G01N33/5076 , G01N2500/02 , G01N2500/10 , G01N2800/347
摘要： The present invention concerns bioactive renal cell populations, in particular a B2 cell population comprising an enriched population of tubular cells and wherein the renal cell population is depleted of a B1 cell population, renal cell constructs, and methods of screening test agents using the bioactive renal cell populations.
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公开(公告)号：EP2352529B1
公开(公告)日：2018-07-11
申请号：EP09753285.7
申请日：2009-11-04
申请人： inRegen
发明人： LUDLOW, John, W. , JAYO, Manuel, J. , BASU, Joydeep , BERTRAM, Timothy, A. , GENHEIMER, Christopher , GUTHRIE, Kelly, I. , ILAGAN, Roger , JAIN, Deepak , KNIGHT, Oluwatoyin , PAYNE, Richard , QUINLAN, Sarah, F. , RAPOPORT, H., Scott , SANGHA, Namrata
CPC分类号： A61F2/042 , A61L27/18 , A61L27/3804 , A61L27/3826 , A61L27/3882 , A61L2430/22 , C08L67/04
摘要： The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
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公开(公告)号：EP2662440B1
公开(公告)日：2018-04-25
申请号：EP13170810.9
申请日：2009-11-12
申请人： inRegen
发明人： Presnell, Sharon , Bruce, Andrew , Wallace, Shay M. , Choudhury, Sumana , Kelley, Russell W. , Jayo, Manuel J. , Werdin, Eric S. , Tatsumi, Patricia D. , Reinsch, Jessica J. , Bertram, Timothy A. , Knight, Oluwatoyin A. , Rapoport, Scott H. , Ilagan, Roger M.
CPC分类号： A61K35/22 , A61K35/12 , C12N5/0686 , C12N2500/02
摘要： The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
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公开(公告)号：EP3567099A1
公开(公告)日：2019-11-13
申请号：EP19168775.5
申请日：2013-10-24
申请人： inRegen
发明人： BASU, Joydeep , GUTHRIE, Kelly , JUSTEWICZ, Dominic , BURNETTE, Teresa , BRUCE, Andrew , KELLEY, Russell , LUDLOW, John, W.
IPC分类号： C12N5/071
摘要： The present invention concerns enriched heterogenous mammalian renal cell populations characterized by biomarkers and methods of making and using the same.
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公开(公告)号：EP3461507A8
公开(公告)日：2019-06-05
申请号：EP18175242.9
申请日：2009-11-04
申请人： inRegen
发明人： LUDLOW, John, W. , JAYO, Manuel, J. , BASU, Joydeep , BERTRAM, Timothy, A. , GENHEIMER, Christopher , GUTHRIE, Kelly, I. , ILAGAN, Roger , JAIN, Deepak , KNIGHT, Oluwatoyin , PAYNE, Richard , QUINLAN, Sarah, F. , RAPOPORT, H., Scott , SANGHA, Namrata
摘要： The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
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公开(公告)号：EP3461507A1
公开(公告)日：2019-04-03
申请号：EP18175242.9
申请日：2009-11-04
申请人： inRegen
发明人： LUDLOW, John, W. , JAYO, Manuel, J. , BASU, Joydeep , BERTRAM, Timothy, A. , GENHEIMER, Christopher , GUTHRIE, Kelly, I. , ILAGAN, Roger , JAIN, Deepak , KNIGHT, Oluwatoyin , PAYNE, Richard , QUINLAN, Sarah, F. , RAPOPORT, H., Scott , SANGHA, Namrata
摘要： The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
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