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公开(公告)号:EP2911758B1
公开(公告)日:2018-01-10
申请号:EP13848496.9
申请日:2013-10-25
申请人: Cyclopharm Ltd.
发明人: LE, Van So , MORCOS, Nabil , McBRAYER, James
CPC分类号: G21G1/0005 , A61K51/1286
摘要: A system using a radioisotope concentrator device comprising a body having at least one injection port and at least one valve being configurable between a first open configuration for allowing fluid communication between the at least one injection port and the concentrator column and a second open configuration to prevent fluid communication between the at least one injection port and the concentrator column in use, the system further comprising an injection device comprising an eluent for eluting through the concentrator column via the at least one injection port when the at least one valve of the radioisotope concentrator device is in a selected open configuration in use.
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公开(公告)号:EP2029178B1
公开(公告)日:2012-03-14
申请号:EP07733302.9
申请日:2007-06-21
发明人: HEMSTAD, Stig
CPC分类号: A61K51/1286
摘要: The present invention relates to improved radiopharmaceutical compositions in sealed containers, where the container closure has an ETFE (ethylene-tetrafluoroethylene copolymer) coating. Also disclosed are kits for radiopharmaceutical preparation using the sealed containers, as well as methods of preparation of radiopharmaceuticals using the sealed containers.
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公开(公告)号:EP3122709B1
公开(公告)日:2018-12-12
申请号:EP15712660.8
申请日:2015-03-30
CPC分类号: A61K51/1286 , B01J19/004 , B29C65/747 , B29K2101/12 , B29L2023/00 , B65B5/04 , C07B59/00 , C07B2200/05
摘要: The present invention relates to systems and methods to facilitate replacement between runs of a kit or cassette from an automated radiosynthesis device located in a hot cell. The method and apparatus of the invention enable automated disconnection of the outlet line by sealing the tubing hermetically by means of heat and by cutting the tubing where it is sealed in such a way that there is no risk of environmental contamination with radioactive material. The invention enables disconnection of the outlet line without manual intervention before opening the shielded enclosure.
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公开(公告)号:EP2911758A4
公开(公告)日:2016-07-20
申请号:EP13848496
申请日:2013-10-25
申请人: CYCLOPHARM LTD
发明人: LE VAN SO , MORCOS NABIL , MCBRAYER JAMES
CPC分类号: G21G1/0005 , A61K51/1286
摘要: A system using a radioisotope concentrator device comprising a body having at least one injection port and at least one valve being configurable between a first open configuration for allowing fluid communication between the at least one injection port and the concentrator column and a second open configuration to prevent fluid communication between the at least one injection port and the concentrator column in use, the system further comprising an injection device comprising an eluent for eluting through the concentrator column via the at least one injection port when the at least one valve of the radioisotope concentrator device is in a selected open configuration in use.
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公开(公告)号:EP3122709A1
公开(公告)日:2017-02-01
申请号:EP15712660.8
申请日:2015-03-30
IPC分类号: C07B59/00
CPC分类号: A61K51/1286 , B01J19/004 , B29C65/747 , B29K2101/12 , B29L2023/00 , B65B5/04 , C07B59/00 , C07B2200/05
摘要: The present invention relates to systems and methods to facilitate replacement between runs of a kit or cassette from an automated radiosynthesis device located in a hot cell. The method and apparatus of the invention enable automated disconnection of the outlet line by sealing the tubing hermetically by means of heat and by cutting the tubing where it is sealed in such a way that there is no risk of environmental contamination with radioactive material. The invention enables disconnection of the outlet line without manual intervention before opening the shielded enclosure.
摘要翻译: 本发明涉及有助于从位于热细胞中的自动放射合成装置替换试剂盒或盒的运行的系统和方法。 本发明的方法和装置能够通过用热气密封管道并通过切割其密封的管道以使得不存在放射性材料的环境污染的风险来自动断开出口管线。 在打开屏蔽外壳之前,本发明能够在没有手动干预的情况下断开出线。
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公开(公告)号:EP2911758A1
公开(公告)日:2015-09-02
申请号:EP13848496.9
申请日:2013-10-25
申请人: Cyclopharm Ltd.
发明人: LE, Van So , MORCOS, Nabil , McBRAYER, James
IPC分类号: B01D15/04 , B01D59/28 , G21G1/04 , G21G4/08 , A61K103/00
CPC分类号: G21G1/0005 , A61K51/1286
摘要: A system using a radioisotope concentrator device comprising a body having at least one injection port and at least one valve being configurable between a first open configuration for allowing fluid communication between the at least one injection port and the concentrator column and a second open configuration to prevent fluid communication between the at least one injection port and the concentrator column in use, the system further comprising an injection device comprising an eluent for eluting through the concentrator column via the at least one injection port when the at least one valve of the radioisotope concentrator device is in a selected open configuration in use.
摘要翻译: 一种使用放射性同位素浓缩器装置的系统,其包括具有至少一个注射口和至少一个阀的主体,所述至少一个阀可配置在用于允许所述至少一个注射口和浓缩器柱之间的流体连通的第一打开配置与第二打开配置之间以防止 所述至少一个注射端口与所述浓缩器柱之间在使用中流体连通,所述系统还包括注射装置,所述注射装置包括洗脱液,用于当所述放射性同位素浓缩器装置的所述至少一个阀门通过所述至少一个注射端口洗脱穿过所述浓缩器柱时 处于正在使用的选定打开配置中。
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公开(公告)号:EP2453881A2
公开(公告)日:2012-05-23
申请号:EP10734625.6
申请日:2010-07-15
申请人: Georgia Health Sciences University Research Institute, Inc. , Savannah River Nuclear Solutions, Llc
发明人: LI, Shuyi , DYNAN, William, S. , WICKS, George , SERKIZ, Steven
IPC分类号: A61K9/50
CPC分类号: A61K9/50 , A61K9/0019 , A61K9/501 , A61K9/5036 , A61K31/721 , A61K51/1286
摘要: The present invention includes compositions of porous-wall hollow glass microspheres and one or more biomolecules, wherein the one or more biomolecules are positioned within a void location within the hollow glass microsphere, and the use of such compositions for the diagnostic and/or therapeutic delivery of biomolecules.
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公开(公告)号:EP2029178A2
公开(公告)日:2009-03-04
申请号:EP07733302.9
申请日:2007-06-21
发明人: HEMSTAD, Stig
CPC分类号: A61K51/1286
摘要: The present invention relates to improved radiopharmaceutical compositions in sealed containers, where the container closure has an ETFE (ethylene-tetrafluoroethylene copolymer) coating. Also disclosed are kits for radiopharmaceutical preparation using the sealed containers, as well as methods of preparation of radiopharmaceuticals using the sealed containers.
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