公开(公告)号：EP2741807A4

公开(公告)日：2015-04-08

申请号：EP12833552

申请日：2012-08-13

申请人： ABIOMED INC ,  DOWLING ROB ,  KUNG BOB ,  SPENCE PAUL A ,  SIESS THORSTEN ,  SPANIER GERD ,  GRATZ ERIC ,  HASTIE CAITLYN

发明人： DOWLING ROB ,  KUNG BOB ,  SPENCE PAUL ,  SIESS THORSTEN ,  SPANIER GERD ,  GRATZ ERIC ,  HASTIE CAITLYN

IPC分类号： A61M1/10 ,  A61B17/11 ,  A61F2/06 ,  A61M1/36

CPC分类号： A61M1/1008 ,  A61B17/11 ,  A61B2017/00884 ,  A61B2017/1135 ,  A61F2/0077 ,  A61F2/064 ,  A61F2250/0026 ,  A61M1/101 ,  A61M1/1032 ,  A61M1/106 ,  A61M1/107 ,  A61M1/12 ,  A61M1/122 ,  A61M1/3653 ,  A61M1/3655 ,  A61M25/0043 ,  A61M25/0071 ,  A61M25/0074 ,  A61M2025/006 ,  A61M2206/10

摘要： A blood flow conduit includes a first conduit portion defining a first portion of a lumen and blood flow path, and a second conduit portion defining a second portion of a lumen and blood flow path. The first portion of the lumen has a smoother surface for contacting the blood flow than the second portion of the lumen. A discontinuity such as a tip portion is positioned between the first and second portions of the lumen.

摘要翻译： 血流导管包括限定内腔和血液流动路径的第一部分的第一导管部分和限定内腔和血液流动路径的第二部分的第二导管部分。 内腔的第一部分具有比内腔的第二部分更接近血流的平滑表面。 诸如尖端部分的不连续性位于内腔的第一和第二部分之间。

公开(公告)号：EP2427230B1

公开(公告)日：2014-12-17

申请号：EP10718497.0

申请日：2010-04-29

申请人： ECP Entwicklungsgesellschaft mbH

发明人： LIEBING, Reiner

IPC分类号： A61M1/10 ,  F04D29/18 ,  F04D29/38

CPC分类号： F04D29/242 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1024 ,  A61M1/1031 ,  A61M1/1032 ,  A61M1/1034 ,  A61M1/1036 ,  A61M1/122 ,  A61M1/125 ,  F04C2/02 ,  F04C14/22 ,  F04D29/043 ,  F04D29/046 ,  F04D29/181 ,  F04D29/528 ,  Y10S415/90

公开(公告)号：EP0748234A1

公开(公告)日：1996-12-18

申请号：EP95910623.0

申请日：1995-03-06

申请人： THORATEC LABORATORIES CORPORATION

发明人： POTTER, David, Stuart ,  WHEELDON, Dereck, Ronald ,  McCARTHY, Terence, Michael ,  POTTER, Charles, David, Ogilvy

IPC分类号： A61M1

CPC分类号： A61M1/106 ,  A61M1/10 ,  A61M1/101 ,  A61M1/1032 ,  A61M1/1062 ,  A61M1/1065

摘要： Ventricular assist devices are used to pump blood in conjunction with the natural heat to assist it. Blood is pumped by subjecting a membrane in the VAD to alternate high and low pressures. The present invention provides a driver for at least one pneumatically-actuated ventricular assist device (VAD), comprising a housing adapted to be carried by a patient, the housing mounting: a single pump arranged to generate gas flow for performing both the blood-filling and the blood-emptying operations of the at least one VAD, a switching valve for alternately communicating the inlet and outlet of the pump with the at least one VAD, vacuum relief means also communicating with the inlet of said pump so that the at least one VAD is subjected to a predetermined negative pressure when performing blood-filling, a battery, and a controller for controlling the operation of the driver. The use of a single pump provides a lighter, more compact VAD driver than the prior art drivers which use two pumps. The housing mounting all the necessary equipment for the driver enables the driver to be fully portable and carried by a patient, thus increasing their quality of life. In a preferred embodiment the VAD communicates with the inlet of the pump via a plenum chamber (1) at low pressure (partial vacuum) and the pump (2) is fully enclosed within the plenum chamber.

公开(公告)号：EP0371985B1

公开(公告)日：1994-08-17

申请号：EP88906364.0

申请日：1988-06-07

申请人： KLETSCHKA, Harold D.

发明人： KLETSCHKA, Harold D.

IPC分类号： F04D13/02 ,  F04D29/62 ,  A61M1/10

CPC分类号： A61M1/1034 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/1025 ,  A61M1/1032 ,  A61M1/1036 ,  F04D13/024 ,  F04D13/04 ,  F04D29/628

摘要： A rotary pump mechanism (1) which is comprised of a coupling section (2) that couples an impeller (7) and a driving member (16) for driving the coupling section and, in turn, the impeller. The coupling section incorporates most of the components (19, 30) of the pump that wear out and are expensive. As a result, the impeller can be disposed of without disposing of other components. The coupling section can also be changed for continuous operation of a single impeller. Although the preferred application of the invention is in the area of pumping blood and other biological fluids, the disclosed invention has utility in any application where it is desirable to turn an ''impeller-like'' element.

公开(公告)号：EP1070511A4

公开(公告)日：2001-01-24

申请号：EP99912100

申请日：1999-04-05

申请人： MIYAWAKI FUJIO

发明人： MIYAWAKI FUJIO

IPC分类号： A61M1/10

CPC分类号： A61M1/1086 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1032 ,  A61M1/1037 ,  A61M1/106 ,  A61M1/1096 ,  A61M1/12 ,  A61M2205/3334

摘要： An auxiliary mechanical heart (10) consisting of a blood tube (14) by which the blood ejected from the heart ventricle is fed into the auxiliary mechanical heart; a one-way valve (22) provided in the blood tube which opens exclusively toward the auxiliary mechanical heart side; an afterload regulatory chamber (11) in which the blood ejected from the heart ventricle is tentatively pooled; a pressure sensor (23) by which the pressure in the afterload regulatory chamber (11) is detected; a blood pump (25); a driving controller (26) for the pump; a blood tube (16) for the arterial blood; and a probe (27) and a blood flow meter (28) for measuring the blood flow rate of the blood pump (25). The pressure in the afterload regulatory chamber (11) is controlled so that the one-way valve (22) is closed in the ventricular diastolic phase while, in the ventricular systolic phase, the whole blood ejected from the heart ventricle flows toward the afterload regulatory chamber (11). Thus, this novel auxiliary mechanical heart is elaborated so that the self-heart can eject the blood at a low ejection resistance and effect sufficient dilation and contraction.

公开(公告)号：EP1070511A1

公开(公告)日：2001-01-24

申请号：EP99912100.7

申请日：1999-04-05

申请人： Miyawaki, Fujio

发明人： Miyawaki, Fujio

IPC分类号： A61M1/10

CPC分类号： A61M1/1086 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1032 ,  A61M1/1037 ,  A61M1/106 ,  A61M1/1096 ,  A61M1/12 ,  A61M2205/3334

摘要： A ventricular assist device 10 includes a blood conduit 14, which carries the blood ejected from the ventricle to the ventricular assist device, a one-way valve 22, which is provided in the blood conduit and can open only toward the ventricular assist device, an afterload-controlling chamber 11, which temporarily stores the blood ejected from the ventricle, a pressure sensor 23, which measures the pressure in the afterload-controlling chamber, a blood pump 25 and a control unit 26 thereof, a blood conduit 16 that carries the blood to an artery, and a probe 27 for measuring blood flow rate and a flowmeter 28, which control the flow rate of the blood pump 25. The pressure of the afterload-controlling chamber 11 is controlled so as to keep the one-way valve closed during ventricular diastole, and also controlled so as to direct all the blood ejected from the ventricle into the afterload-controlling chamber 11 during ventricular systole. Therefore, a new ventricular assist device can be provided, which enables the native heart to eject blood with very low ejection resistance and ensures sufficient ventricular relaxation and filling.

摘要翻译： 心室辅助装置10包括：血液导管14，其将从心室喷射的血液输送至心室辅助装置;单向阀22，其设置在血液导管中并且可以仅朝向心室辅助装置打开; 临时储存从心室射出的血液的后负荷控制室11，测量后负荷控制室内的压力的压力传感器23，血液泵25及其控制单元26，血液导管16， 血液流向动脉，以及测量血液流速的探针27和控制血液泵25的流量的流量计28.控制后负荷控制室11的压力以保持单向阀 在心室舒张期闭合，并且还受到控制以在心室收缩期间将从心室射出的所有血液引导至后负荷控制室11。 因此，可以提供新的心室辅助装置，其使得天然心脏能够以非常低的排出阻力排出血液并且确保充分的心室松弛和充盈。

公开(公告)号：EP0371985A4

公开(公告)日：1991-07-03

申请号：EP88906364

申请日：1988-06-07

申请人： KLETSCHKA, HAROLD D.

发明人： KLETSCHKA, HAROLD D.

IPC分类号： A61M1/10 ,  F04D13/02 ,  F04D13/04 ,  F04D29/62 ,  F04B17/00

CPC分类号： A61M1/1034 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/1025 ,  A61M1/1032 ,  A61M1/1036 ,  F04D13/024 ,  F04D13/04 ,  F04D29/628

公开(公告)号：EP0371985A1

公开(公告)日：1990-06-13

申请号：EP88906364.0

申请日：1988-06-07

申请人： KLETSCHKA, Harold D.

发明人： KLETSCHKA, Harold D.

IPC分类号： A61M1 ,  F04D13 ,  F04D29

CPC分类号： A61M1/1034 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/1025 ,  A61M1/1032 ,  A61M1/1036 ,  F04D13/024 ,  F04D13/04 ,  F04D29/628

摘要： Un mécanisme de pompe rotative (1) est constitué d'une section de couplage (2) qui assure l'accouplement entre une roue hélice (7) et un organe d'entraînement (16) pour entraîner la section de couplage et, à son tour, la roue hélice. La section de couplage comporte la plupart des composants (19, 30) de la pompe qui s'usent et qui sont coûteux. En conséquence, la roue hélice peut être remplacée sans avoir à remplacer d'autres composants. On peut également changer la section de couplage pour avoir un fonctionnement continu d'une seule roue hélice. Bien que l'application préférée de l'invention concerne le domaine du pompage de sang et autres fluides biologiques, l'invention décrite est utile dans toute application où il est souhaitable de mettre en rotation un élément semblable à une roue hélice.

公开(公告)号：EP3120880A1

公开(公告)日：2017-01-25

申请号：EP15177575.6

申请日：2015-07-20

申请人： Berlin Heart GmbH ,  Universität Zürich

发明人： OPFERMANN, Dr., Ulrich Tim ,  ARNDT, Dr., Andreas ,  FALK, Prof. Dr., Volkmar

IPC分类号： A61M1/10 ,  A61M1/12

CPC分类号： A61M1/125 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1024 ,  A61M1/1029 ,  A61M1/1031 ,  A61M1/1032 ,  A61M1/1034 ,  A61M1/1096 ,  A61M1/1098 ,  A61M1/122 ,  A61M1/127

摘要： Die Erfindung bezieht sich auf ein implantierbares Pumpensystem zur Förderung von Blut innerhalb eines Patientenkörpers mit einer Blutpumpe (2, 3, 8), die eine Flüssigkeit in einer Axialrichtung (7) fördert und die einen rotierend antreibbaren Rotor (3) sowie ein den Rotor umgebendes Pumpengehäuse (2) aufweist, sowie ein Stützrohr (6), in dem das Pumpengehäuse (2) angeordnet und gehalten ist, wobei zwischen dem Stützrohr und dem Pumpengehäuse ein Ringspalt (33) gebildet ist. Auf diese Weise wird durch die Kombination einer Strömung durch das Pumpengehäuse (2) einerseits und den Ringspalt (33) andererseits eine nahezu physiologische Blutströmung ermöglicht.

摘要翻译： 本发明涉及一种用于在患者体内输送血液的可植入泵系统，其具有在轴向方向上输送流体的血泵，并且包括可旋转驱动的转子以及围绕转子的泵壳，以及 支撑管，其中泵壳体被布置和保持在其中，其中在支撑管和泵壳体之间形成环形间隙。 以这种方式，通过一方面通过泵壳体的流动与另一方面的环形间隙的组合，可以实现几乎生理的血液流动。

公开(公告)号：EP1617888A2

公开(公告)日：2006-01-25

申请号：EP04760179.4

申请日：2004-04-23

申请人： Biovalve Technologies, Inc.

发明人： GONNELLI, Robert, R.

IPC分类号： A61M5/145

CPC分类号： A61M5/16877 ,  A61M1/1032 ,  A61M5/1452 ,  A61M5/14526 ,  A61M5/14593 ,  A61M5/155 ,  A61M37/0015 ,  A61M2005/14264 ,  A61M2005/14506 ,  A61M2005/14513 ,  A61M2037/0023 ,  A61M2037/0038 ,  A61M2037/0046 ,  A61M2250/00 ,  F04B9/103 ,  F04B9/1095 ,  F04B15/02 ,  F04B53/14 ,  F04B53/16

摘要： Presently disclosed is a hydraulic pump device and its use thereof, especially in a fluid delivery system. In one embodiment, the fluid delivery system is an inexpensive, single-use device for slow dosing medicament applications. The fluid delivery system may employ a spring-compressed bellows crank or other combination of simple mechanisms operating according to the well-known peristaltic principle to force a volume of ultrapure bio-inert hydraulic fluid through an aperture, thereby expanding one chamber of a two chamber hydraulic cylinder. The second, fluid storage chamber, containing the medicament, is emptied through a conventional orifice in response to the expansion of the pump chamber. The medicament may thence flow through any suitable infusion set into a patient removeably attached thereto.

摘要翻译： 流体输送装置包括具有液压流体的液压泵室。 流体储存器联接到液压泵室，并且构造成容纳可递送给患者的流体。 第一致动器联接到液压泵室，并且构造成对液压泵室加压并且构造成将能量通过液压泵室传递到流体储存器。 第二致动器联接到液压泵室并且构造成对液压泵室加压并且构造成将能量通过液压泵室传递到流体储存器。