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1.发明公开
公开(公告)号：EP4414025A2
公开(公告)日：2024-08-14
申请号：EP24184571.8
申请日：2020-08-25
IPC分类号： A61N1/372
CPC分类号： A61N1/36062 , A61N1/36185 , A61N1/36164 , A61N1/36178 , A61N1/37247
摘要： An external device configured to communicate with an implantable stimulator device implanted in a patient, comprising: control circuitry configured to: provide stimulation parameters for the patient to address a symptom of the patient, provide a schedule for the provision of scheduled boluses of stimulation for the patient, wherein each scheduled bolus comprises a first duration during which stimulation is applied to the patient in accordance with the stimulation parameters, wherein the scheduled boluses are separated by off times of a second duration when no stimulation is provided to the patient, receive at a first time an input at a graphical user interface of the external device to immediately provide an additional bolus of stimulation, and transmit instructions to cause the implantable stimulator device to provide at least the scheduled boluses to neural tissue of the patient according to the schedule.
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公开(公告)号：EP3102283B1
公开(公告)日：2018-02-28
申请号：EP15702346.6
申请日：2015-01-21
CPC分类号： A61N1/36164 , A61N1/0551 , A61N1/36071 , A61N1/36125 , A61N1/36132 , A61N1/3615 , A61N1/37247
摘要： A neuromodulation system configured for providing sub-threshold neuromodulation therapy to a patient. The neuromodulation system comprises a neuromodulation lead having at least one electrode configured for being implanted along a spinal cord of a patient, a plurality of electrical terminals configured for being respectively coupled to the at least one electrode, modulation output circuitry configured for delivering sub-threshold modulation energy to active ones of the at least one electrode, and control/processing circuitry configured for selecting a percentage from a plurality of percentages based on a known longitudinal location of the neuromodulation lead relative to the spinal cord, computing an amplitude value as a function of the selected percentage, and controlling the modulation output circuitry to deliver sub-threshold modulation energy to the patient at the computed amplitude value.
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公开(公告)号：EP3197540A1
公开(公告)日：2017-08-02
申请号：EP15771486.6
申请日：2015-09-22
IPC分类号： A61N1/36
CPC分类号： A61N1/36071 , A61N1/0551 , A61N1/3605 , A61N1/36128 , A61N1/36132 , A61N1/3615 , A61N1/36164
摘要： A system example may include electrodes operationally positioned for use in delivering sub-perception neural modulation, a neural modulator configured to use at least some electrodes to generate a modulation field, and a feedback system configured to receive a feedback signal that a generated modulation field provides a perceived or measurable response. A control system may implement a calibration process including controlling the neural modulator to generate the modulation field using a first and second stimulus pulse with a first and second pulse width, respectively, and using the feedback system to determine a first and second reference point that represents an intensity of the modulation field generated using the first and second pulse widths, respectively, that provides the response, and deriving sub-perception calibration data specific to sub-perception modulation delivered using a sub-perception pulse with a sub-perception pulse width.
摘要翻译： 系统示例可以包括操作地定位用于传递子感知神经调制的电极，被配置为使用至少一些电极来产生调制场的神经调制器，以及被配置为接收所生成的调制场提供的反馈信号的反馈系统 一种可感知或可衡量的回应。 控制系统可实施校准过程，包括分别使用具有第一和第二脉冲宽度的第一和第二刺激脉冲来控制神经调制器以生成调制场，并且使用反馈系统来确定表示第一和第二参考点的第一和第二参考点 分别使用提供响应的第一和第二脉冲宽度生成的调制场的强度，以及导出特定于使用具有子感知脉冲宽度的子感知脉冲递送的子感知调制的子感知校准数据。
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4.发明公开
公开(公告)号：EP3157619A1
公开(公告)日：2017-04-26
申请号：EP15809234.6
申请日：2015-06-17
申请人： Mower, Morton M.
发明人： Mower, Morton M.
IPC分类号： A61N1/05
CPC分类号： A61N1/365 , A61N1/32 , A61N1/326 , A61N1/36002 , A61N1/36007 , A61N1/36121 , A61N1/36164 , A61N1/3628
摘要： A method and device for performing electrical current therapy on biological tissue. The device can operate continuously as a bio-energetic thermostat to continuously provide electrical current therapy, or based on sensing parameters and providing electrical current therapy only when the parameters indicate that the electrical current therapy is to be applied.
摘要翻译： 一种用于对生物组织进行电流治疗的方法和装置。 该装置可作为生物能量恒温器连续运行以持续提供电流治疗，或基于感测参数并仅在参数指示要施加电流疗法时提供电流治疗。
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5.发明公开DEVICES FOR CONTROLLING HIGH FREQUENCY SPINAL CORD MODULATION FOR INHIBITING PAIN, AND ASSOCIATED SYSTEMS 审中-公开为了控制高频脊髓脉宽调制在预防疼痛的设备和相关系统
公开(公告)号：EP3097946A1
公开(公告)日：2016-11-30
申请号：EP16173569.1
申请日：2010-04-22
申请人： Nevro Corporation
CPC分类号： A61N1/36071 , A61N1/0551 , A61N1/0553 , A61N1/06 , A61N1/36021 , A61N1/3605 , A61N1/36157 , A61N1/36164 , A61N1/36167 , A61N1/36171 , A61N1/36175 , A61N1/36182 , A61N1/37235 , A61N1/37241 , A61N1/37247 , A61N1/37264 , A61N1/3787
摘要： Selective high-frequency spinal chord modulation for inhibiting pain with reduced side affects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal chord region to address low back pain without creating unwanted sensory and/or motor side affects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications. In particular embodiments, aspects of the foregoing modulation therapies may be implemented by systems and devices that have simplified functionalities.
摘要翻译： 选择性高频脊髓调制具有减小的一侧为抑制疼痛影响以及相关的系统和方法是游离缺失盘。 在具体实施方案中，从约1.5 kHz到约50kHz范围内的高频率调制可以被施加到患者的脊髓区域，以解决腰痛而不产生不希望的感官和/或马达侧影响。 在其它实施方案中，在具有类似参数雅舞蹈调制可应用于其他脊柱或周边位置，以解决其它适应症。 在特定实施例中，前述的调制疗法的方面可以通过系统来实现和设备thathave简化功能。
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6.发明公开
公开(公告)号：EP4392128A1
公开(公告)日：2024-07-03
申请号：EP22769515.2
申请日：2022-08-17
CPC分类号： A61N1/36062 , A61N1/0551 , A61N1/36071 , A61N1/37247 , G16H20/30 , G16H40/63 , A61N1/36164 , A61N1/36146 , A61N1/36139 , A61N1/3614 , A61B5/7435 , A61B5/686
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公开(公告)号：EP4331474A3
公开(公告)日：2024-05-22
申请号：EP24153243.1
申请日：2020-06-15
申请人： Medtronic, Inc.
发明人： DAVIES, Lachlan , MCCAMMON, Sheryl , CLELAND, Andrew J. , GOODMAN KEISER, Melanie D. , TAN, Ye , JOHANEK, Lisa M. , TORGERSON, Nathan A.
CPC分类号： A61N1/36062 , A61N1/36071 , A61N1/36132 , A61N1/36164 , A61N1/3615 , A61N1/36175 , A61B5/1116 , A61B5/4836
摘要： In some examples, a medical device is configured to deliver sub-threshold electrical stimulation therapy to a patient at a stimulation intensity that is significantly less than a perception or paresthesia threshold intensity level for the patient. The medical device may deliver the sub-threshold electrical stimulation therapy to a first anatomical location near a spine of a patient. The first anatomical location may be below a T9-10 spinal disc space in a lateral view of the patient or within 2 millimeters of a midline of the spine of the patient or both.
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公开(公告)号：EP3381508A1
公开(公告)日：2018-10-03
申请号：EP18163564.0
申请日：2018-03-23
发明人： Kibler, Andrew B. , Müssig, Dirk , Baru, Marcelo
IPC分类号： A61N1/36
CPC分类号： A61N1/36062 , A61N1/0502 , A61N1/0553 , A61N1/36017 , A61N1/36021 , A61N1/36031 , A61N1/36034 , A61N1/36057 , A61N1/36071 , A61N1/36132 , A61N1/36157 , A61N1/36164 , A61N1/36171 , A61N1/36175 , A61N1/36178
摘要： The present invention relates to a device for neurostimulation, with a pulse generator capable of generating current comprising pulses, and at least a first pair of electrodes connected to the pulse generator, wherein the device provides a user-programmable therapy strength parameter configuration and at least two current parameter configurations for neurostimulation stored in the pulse generator, the current parameter configurations being controlled by the therapy strength configuration, and wherein at least one of the current parameter configurations is associated with a level of paresthesia sensation of a patient and at least one of the current parameter configurations is associated with a paresthesia-free therapy for the patient, wherein the association between the therapy strength parameter and the current parameter configurations uniquely adjusts the current parameter configurations based on their paresthesia or paresthesia-free intent, and when the neurostimulation is performed using said parameter configurations. Particularly, the current parameter configurations comprise parameters such as pulse trains, pulse frequencies, duty cycling, and amplitudes of the current.
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9.发明公开
公开(公告)号：EP3257552A2
公开(公告)日：2017-12-20
申请号：EP17163934.7
申请日：2017-03-30
申请人： Nevro Corp.
发明人： LEE, Dongchul
IPC分类号： A61N1/36
CPC分类号： A61N1/36142 , A61N1/0551 , A61N1/08 , A61N1/36034 , A61N1/3605 , A61N1/36062 , A61N1/36071 , A61N1/36139 , A61N1/36164 , A61N1/36171 , A61N1/37241
摘要： Systems and methods for identifying and treating patients with high frequency electrical signals. A representative method for identifying a patient as a candidate for pain treatment includes identifying a first sensory threshold, delivering an electrical signal to a neural population of the patient at a frequency in a frequency range of 1.5 kHz to 100 kHz and, while and/or after delivering the electrical signal to the patient, identifying a second sensory threshold of the patient. If the second sensory threshold is less than the first, the method can include identifying the patient as a candidate for receiving an electrical signal at a frequency in the foregoing range for pain treatment.
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公开(公告)号：EP1524007B1
公开(公告)日：2017-03-01
申请号：EP04256377.5
申请日：2004-10-15
IPC分类号： A61N1/36
CPC分类号： A61N1/36135 , A61N1/3601 , A61N1/36164 , A61N1/37205 , A61N1/37223
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