METHODS AND SYSTEMS FOR CAMPTOTHECIN ANALOG SYNTHESIS
    6.
    发明公开
    METHODS AND SYSTEMS FOR CAMPTOTHECIN ANALOG SYNTHESIS 审中-公开
    用于结肠平滑肌综合征的方法和系统

    公开(公告)号:EP3209666A1

    公开(公告)日:2017-08-30

    申请号:EP15852329.0

    申请日:2015-10-20

    发明人: LI, Bin-Feng YUAN, Ke

    IPC分类号: C07D491/22

    CPC分类号: C07F7/1892 C07F7/0814

    摘要: Methods and systems for making camptothecin analogs and intermediates are provided. Aspects include safer and lower cost methodologies for making camptothecin analogs and intermediates from synthetic materials. In another aspect, the methods and systems can achieve a yield of the camptothecin analogs greater than about 0.4%.

    摘要翻译: 提供了制备喜树碱类似物和中间体的方法和系统。 方面包括用合成材料制造喜树碱类似物和中间体的更安全和更低成本的方法。 另一方面,所述方法和系统可以实现大于约0.4%的喜树碱类似物的产率。