利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

109 条记录 (耗时 0.024 秒)

    ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS
    2.
    发明公开
    ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS 审中-公开
    有机成分HALBLEITERSCHICHT MIT磷酸羟丁酯

    公开(公告)号：EP3171418A1

    公开(公告)日：2017-05-24

    申请号：EP15195877.4

    申请日：2015-11-23

    申请人： Novaled GmbH

    发明人： Senkovskyy, Volodymyr

    IPC分类号： H01L51/00 ,  H01L51/50 ,  C07F9/50 ,  C07F9/53

    CPC分类号： H01L51/5072 ,  C07F9/5325 ,  C07F9/5765 ,  C07F9/65068 ,  C07F9/65517 ,  C07F9/65522 ,  C07F9/65586 ,  C07F9/6561 ,  H01L51/0052 ,  H01L51/0073 ,  H01L51/5076

    摘要： The present invention relates to an organic semiconductive layer which is an electron transport layer and/or an electron injection layer and/or an n-type charge generation layer, the organic semiconductive layer comprising at least one compound of formula (1)

    wherein R 1 and R 2 are each independently selected from C 1 to C 16 alkyl; Ar 1 is selected from C 6 to C 14 arylene or C 3 to C 12 heteroarylene; Ar 2 is independently selected from C 14 to C 40 arylene or C 8 to C 40 heteroarylene; R 3 is independently selected from H, C 1 to C 12 alkyl or C 10 to C 20 aryl; wherein each of Ar 1 , Ar 2 and R 3 may each independently be unsubstituted or substituted with at least one C 1 to C 12 alky group; n is 0 or 1; and m is 1 in case of n = 0; and m is 1 or 2 in case of n = 1, phosphine oxide compounds comprised therein and to organic electroluminescent devices comprising such layers and compounds.

    摘要翻译： 本发明涉及作为电子传输层和/或电子注入层和/或n型电荷产生层的有机半导体层，所述有机半导体层包含至少一种式（1）化合物，其中R 1 和R 2各自独立地选自C 1至C 16烷基; Ar 1选自C 6〜C 14亚芳基或C 3〜C 12亚杂芳基; Ar 2独立地选自C 14至C 40亚芳基或C 8至C 40亚杂芳基; R 3独立地选自H，C 1至C 12烷基或C 10至C 20芳基; 其中Ar 1，Ar 2和R 3各自独立地为未取代的或被至少一个C 1至C 12烷基取代; n为0或1; 在n = 0的情况下m为1; 在n = 1的情况下，m为1或2，其中包含氧化膦化合物和包含这些层和化合物的有机电致发光器件。

    MINOR GROOVE BINDER PHOSPHORAMIDITES AND METHODS OF USE
    6.
    发明公开
    MINOR GROOVE BINDER PHOSPHORAMIDITES AND METHODS OF USE 审中-公开
    MGB-PHOSPHORAMIDITE UND VERWENDUNGSVERFAHREN

    公开(公告)号：EP2736916A1

    公开(公告)日：2014-06-04

    申请号：EP12748296.6

    申请日：2012-07-24

    申请人： Elitech Holding B.V.

    发明人： VOROBIEV, Alexei ,  LUKHTANOV, Eugeny, A.

    IPC分类号： C07H21/00 ,  C07D235/18 ,  C07F9/22

    CPC分类号： C07H21/00 ,  C07D235/18 ,  C07D403/04 ,  C07D519/00 ,  C07F9/65068 ,  C07F9/65583 ,  C07F9/6561 ,  Y02P20/55

    摘要： Minor groove binder phosphoramidites having the formula M-L-PA, wherein M is a minor groove binder comprising a protected heteroaromatic amine, L is a linker, and PA is a phosphoramidite group, have been synthesized. Preferred methods of synthesis include synthesizing a minor groove binder intermediate containing a transiently protected hydroxyl group, protecting heteroaromatic amines of the corresponding minor groove binder intermediate as carbamate intermediates, reacting the carbamate intermediate to remove the transient protecting group to yield carbamate-protected minor groove binder agent as an intermediate with a free hydroxyl group, and converting the intermediate with a free hydroxyl group to the desired minor groove binder phosphoramidite. These minor groove binder phosphoramidites are useful in the preparation of oligonucleotide conjugates, particularly those for use as probes and primers. In preferred methods, an oligonucleotide sequence is synthesized using nucleoside phosphoramidites and the minor groove binder phosphoramidite is incorporated into the oligonucleotide sequence to form a protected oligonucleotide-minor groove binder conjugate. Then, deprotection produces the oligonucleotide-minor groove binder.

    摘要翻译： 具有式M-L-PA的次槽粘合剂亚磷酰胺，其中M是包含受保护的杂芳族胺的小沟粘合剂，L是接头，PA是亚磷酰胺基团。 优选的合成方法包括合成含有瞬时保护的羟基的小沟粘合剂中间体，保护相应的小沟粘合剂中间体的杂芳族胺作为氨基甲酸酯中间体，使氨基甲酸酯中间体反应以除去瞬时保护基团以产生氨基甲酸酯保护的小沟槽结合剂 作为具有游离羟基的中间体，并且将具有游离羟基的中间体转化成所需的次槽粘合剂亚磷酰胺。 这些小沟粘结剂亚磷酰胺可用于制备寡核苷酸缀合物，特别是用作探针和引物的寡核苷酸缀合物。 在优选的方法中，使用核苷亚磷酰胺合成寡核苷酸序列，并将小沟粘合剂亚磷酰胺掺入寡核苷酸序列中以形成受保护的寡核苷酸 - 小沟粘合剂缀合物。 然后，去保护产生寡核苷酸 - 小沟结合剂。

    BENZIMIDAZOLE VASCULAR DAMAGING AGENTS
    10.
    发明授权
    BENZIMIDAZOLE VASCULAR DAMAGING AGENTS 有权
    WITH影响VASKULARISATIONSZERSTÖRENDER的苯并咪唑

    公开(公告)号：EP1140078B1

    公开(公告)日：2007-08-29

    申请号：EP00900294.0

    申请日：2000-01-14

    申请人： Angiogene Pharmaceuticals Ltd

    发明人： DAVIS, Peter David

    IPC分类号： A61K31/4184 ,  A61P9/00 ,  C07D235/32 ,  C07F9/6506

    CPC分类号： C07F9/65068 ,  A61K31/4184 ,  A61K31/675 ,  C07D235/32

    摘要： 5(6)-substituted benzimidazole-2-carbamates of formula (I) wherein Alk is an alkyl group, X is oxygen, sulphur, sulphinyl, sulphonyl, carbonyl (CO), thiocarbonyl (CS), sulphonyloxy, NH, iminomethylene (C=NH), N-hydroxyiminomethylene, N-alkoxyiminomethylene, dialkoxymethylene, 1,3-dioxolan-2yl, 1,1-ethenyl, a group CHR3 or a bond, R1 is hydrogen, alkylaminocarbonyl or alkoxycarbonyl, R2 is hydrogen, alkoxycarbonyl, cyanomethyl, cyanoethyl, alkoxymethyl or acetoxymethyl. R3 is hydrogen, hydroxy, alkoxy or amino, A is an optionally substituted aromatic, optionally substituted heteroaromatic, optionally substituted heterocycloalkyl, optionally substituted alkyl or optionally substituted cycloalkyl group and the pharmaceutically acceptable salt, solvates and hydrates thereof, can be used in the preparation of medicaments for the treatment of diseases involving neovascularisation.