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公开(公告)号：EP2898066B1
公开(公告)日：2018-01-31
申请号：EP13779903.7
申请日：2013-09-20
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , A61K9/5123 , B82Y5/00 , C12N2710/20023 , C12N2710/20031 , C12N2770/00023 , C12N2770/00031 , C12N2770/18023 , C12N2770/18031 , C12N2770/34023 , C12N2770/34031 , C12N2770/40023 , C12N2770/40031
摘要： There is described a process for production of metal-coated virus particles or metallic nanoparticles, said process comprising admixing virus particles with plant material with reducing power and a metal salt, wherein the process can be provided in planta or ex planta and the virus particles aid the production of the metal-coated virus particles or metallic nanoparticles.
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2.发明公开NEPOVIRUS COAT PROTEIN FUSION POLYPEPTIDES AND THEIR USE 审中-公开NEPOVIRUSHÜLLPROTEINFUSIONSPOLYPEPTIDE UND DEREN VERWENDUNGEN
公开(公告)号：EP3141600A1
公开(公告)日：2017-03-15
申请号：EP15306396.1
申请日：2015-09-11
申请人： Institut National de la Recherche Agronomique , Université de Strasbourg , Centre National de la Recherche Scientifique
IPC分类号： C12N7/00 , C07K14/085 , C12N15/62
CPC分类号： C07K14/005 , C07K2319/00 , C07K2319/60 , C12N7/00 , C12N2770/18022 , C12N2770/18023
摘要： The present invention relates to novel fusion polypeptides and the uses thereof. The invention particularly relates to conjugated coat proteins derived from nepoviruses, virus-like particles made with such proteins, and the uses thereof. The particles of the invention can expose and/or encage molecules of interest and have utility in various fields such as the pharmaceutical, agro, or veterinary areas.
摘要翻译： 本发明涉及新型融合多肽及其用途。 本发明特别涉及衍生自鼻病毒的共轭外壳蛋白，由这些蛋白质制成的病毒样颗粒及其用途。 本发明的颗粒可以暴露和/或包裹感兴趣的分子，并且在诸如药物，农业或兽医领域的各种领域中具有实用性。
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公开(公告)号：EP3347459A1
公开(公告)日：2018-07-18
申请号：EP16763811.3
申请日：2016-09-09
申请人： Institut National de la Recherche Agronomique , Université de Strasbourg , Centre National de la Recherche Scientifique
CPC分类号： C07K14/005 , C07K2319/00 , C07K2319/60 , C12N7/00 , C12N2770/18022 , C12N2770/18023
摘要： The present invention relates to novel fusion polypeptides and the uses thereof. The invention particularly relates to conjugated coat proteins derived from nepoviruses, virus-like particles made with such proteins, and the uses thereof. The particles of the invention can expose and/or encage molecules of interest and have utility in various fields such as the pharmaceutical, agro, or veterinary areas.
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4.发明公开NANOPARTICLE SYNTHESIS USING PLANT EXTRACTS AND VIRUS 有权NANOPARTIKELSYNTHESE MIT PFLANZENEXTRAKTEN UND VIREN
公开(公告)号：EP2898066A1
公开(公告)日：2015-07-29
申请号：EP13779903.7
申请日：2013-09-20
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , A61K9/5123 , B82Y5/00 , C12N2710/20023 , C12N2710/20031 , C12N2770/00023 , C12N2770/00031 , C12N2770/18023 , C12N2770/18031 , C12N2770/34023 , C12N2770/34031 , C12N2770/40023 , C12N2770/40031
摘要： There is described a process for production of metal-coated virus particles or metallic nanoparticles, said process comprising admixing virus particles with plant material with reducing power and a metal salt, wherein the process can be provided in planta or ex planta and the virus particles aid the production of the metal-coated virus particles or metallic nanoparticles.
摘要翻译： 描述了金属包覆的病毒颗粒或金属纳米颗粒的生产方法，所述方法包括将病毒颗粒与具有还原力的植物材料和金属盐混合，其中该方法可以在植物或外植物中提供，并且病毒颗粒有助于 金属包覆病毒颗粒或金属纳米粒子的生产。
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公开(公告)号：EP2443241A1
公开(公告)日：2012-04-25
申请号：EP10727484.7
申请日：2010-06-15
CPC分类号： C12N15/8202 , A61K9/5184 , A61K47/6901 , A61K2039/5258 , C07K14/005 , C07K2319/00 , C07K2319/21 , C12N7/00 , C12N15/8257 , C12N15/88 , C12N2770/18022 , C12N2770/18023
摘要： The invention provides methods of producing "empty" RNA virus capsids (
e.g. from
Cowpea mosaic virus ) by assembly of viral small (S) and large (L) coat proteins in such a way that encapsidation of native viral RNA is avoided. Aspects of the invention employ
in planta expression of capsid components from DNA vectors encoding the S and L proteins or S-L polyproteins including them. Such capsids have utility for the encapsidation or presentation of foreign proteins or desired payloads.
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