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    Multiple-sample scanner-type fluorescence detection apparatus
    1.
    发明公开
    Multiple-sample scanner-type fluorescence detection apparatus 有权
    Abtastende FluoreszenznachweisvorrichtungfürMehrfachproben。

    公开(公告)号：EP1024355A1

    公开(公告)日：2000-08-02

    申请号：EP00101404.2

    申请日：2000-01-25

    Applicant: Tosoh Corporation

    Inventor： Hayashi, Toshinori ,  Ishiguro, Takahiko

    IPC: G01N21/25 ,  G01N21/64

    CPC classification number: G01N21/645 ,  G01N21/253 ,  G01N35/025 ,  G01N2201/0231 ,  G01N2201/0423 ,  G01N2201/043 ,  G01N2201/0806 ,  G01N2201/0853

    Abstract: A fluorescence detection apparatus is provided which comprises a sample holder (4) for holding stationarily sample vessels deployed along a circle line or concentric circle lines having different radiuses, a partition plate (3) connected to a driving means (7) to be rotatable around the center of the circle line or concentric circle lines, optical means (5) for excitation light and optical means (6) for fluorescence light fixed respectively to the partition plate to be rotatable in integration therewith, a first light guide (1) constituted of numerous optical fibers, a photosensor (2), and a light source (8) for generating the excitation light, wherein the partition plate, the optical means for excitation light, and the optical means for fluorescence are integrally rotated, and thereby the fluorescence of the sample arranged along the circle line is successively detected and the detected fluorescence is transmitted to the photosensor. This fluorescence detection apparatus is useful in real-time monitoring of fluorescence signals, and satisfies the requirements of precise temperature control, quick treatment of many samples, high sensitivity, high reliability, low cost, and small size of the apparatus.

    Abstract translation: 提供了一种荧光检测装置，其包括用于保持沿着圆线展开的固定样品容器的样本保持器（4）或具有不同半径的同心圆线;连接到驱动装置（7）以可旋转的分隔板（3） 圆线或同心圆线的中心，用于激发光的光学装置（5）和用于荧光的光学装置（6），分别固定在分隔板上以与其一体旋转;第一光导（1），由 多个光纤，光电传感器（2）和用于产生激发光的光源（8），其中分隔板，用于激发光的光学装置和用于荧光的光学装置一体地旋转，由此荧光 连续检测沿圆线排列的样品，并将检测到的荧光传输到光电传感器。 该荧光检测装置可以实时监测荧光信号，满足精密温度控制，快速处理多种样品，高灵敏度，高可靠性，低成本，小尺寸等要求。

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