Multiple-sample scanner-type fluorescence detection apparatus
    3.
    发明公开
    Multiple-sample scanner-type fluorescence detection apparatus 有权
    Abtastende FluoreszenznachweisvorrichtungfürMehrfachproben。

    公开(公告)号:EP1024355A1

    公开(公告)日:2000-08-02

    申请号:EP00101404.2

    申请日:2000-01-25

    Abstract: A fluorescence detection apparatus is provided which comprises a sample holder (4) for holding stationarily sample vessels deployed along a circle line or concentric circle lines having different radiuses, a partition plate (3) connected to a driving means (7) to be rotatable around the center of the circle line or concentric circle lines, optical means (5) for excitation light and optical means (6) for fluorescence light fixed respectively to the partition plate to be rotatable in integration therewith, a first light guide (1) constituted of numerous optical fibers, a photosensor (2), and a light source (8) for generating the excitation light, wherein the partition plate, the optical means for excitation light, and the optical means for fluorescence are integrally rotated, and thereby the fluorescence of the sample arranged along the circle line is successively detected and the detected fluorescence is transmitted to the photosensor. This fluorescence detection apparatus is useful in real-time monitoring of fluorescence signals, and satisfies the requirements of precise temperature control, quick treatment of many samples, high sensitivity, high reliability, low cost, and small size of the apparatus.

    Abstract translation: 提供了一种荧光检测装置,其包括用于保持沿着圆线展开的固定样品容器的样本保持器(4)或具有不同半径的同心圆线;连接到驱动装置(7)以可旋转的分隔板(3) 圆线或同心圆线的中心,用于激发光的光学装置(5)和用于荧光的光学装置(6),分别固定在分隔板上以与其一体旋转;第一光导(1),由 多个光纤,光电传感器(2)和用于产生激发光的光源(8),其中分隔板,用于激发光的光学装置和用于荧光的光学装置一体地旋转,由此荧光 连续检测沿圆线排列的样品,并将检测到的荧光传输到光电传感器。 该荧光检测装置可以实时监测荧光信号,满足精密温度控制,快速处理多种样品,高灵敏度,高可靠性,低成本,小尺寸等要求。

    Messkopf
    4.
    发明公开
    Messkopf 失效
    测量头。

    公开(公告)号:EP0327499A1

    公开(公告)日:1989-08-09

    申请号:EP89810061.5

    申请日:1989-01-24

    Abstract: Ein Meßkopf, insbesondere für ein Handgerät zur Er­fassung von photometrischen Daten, verfügt über eine Beleuchtungsoptik mit einer Asphäre, die eine ring­förmig um die Symmetrieachse des Meßkopfes laufende Mulde aufweist, welche im Querschnitt die Gestalt eines Ellipsensegments hat. Die Meßoptik (116) zum Erfassen des vom Meßfleck (57) remittierten Lichtes bildet einen runden Meßfleck (57) auf eine Ellipse am Eintrittsspalt (59) des Monochromators (55) ab, wozu eine sphä­risch/zylindrische Linse (132) sowie ein erster Glas­stab (148) und ein Glasstab (149) verwendet werden, die jeweils zylindrische Flächen (154, 155, 156, 157) aufweisen, deren zugeordnete Zylinderachsen gekreuzt sind.

    Abstract translation: 的测量头,特别是用于检测测光数据的手持式装置,具有与具有一个环状连续约测量头凹部,其在横截面中具有椭圆形段的形状的对称轴的非球面透镜的照明光学系统。 用于从所述测量点(57)检测所述光学测量系统(116)反射的光的形式从圆形测量光斑(57)上的单色器(55)的入口狭缝(59)的椭圆形中,向其中一个球形/柱面透镜(132)和第一玻璃棒 (148)和一玻璃棒(149)时,每个圆柱形表面(154,155,156,157),其相关联的气缸轴线交叉。

    Vorrichtung zur Messung der Lichtstreuung in stark streuenden dispersen Systemen
    6.
    发明公开
    Vorrichtung zur Messung der Lichtstreuung in stark streuenden dispersen Systemen 失效
    Vorrichtung zur Messung der Lichtstreuung in stark streuenden dispersen Systemen。

    公开(公告)号:EP0244789A2

    公开(公告)日:1987-11-11

    申请号:EP87106383.0

    申请日:1987-05-02

    Abstract: Vorrichtung zur Messung der Lichtstreuung in stark streuen­den dispersen Medien. Bei dieser Meßvorrichtung wird aus einer Lichtquelle, bevorzugt aus einem He-Ne Laser Licht in eine Meßzelle gestrahlt, in der sich das zu untersu­chende Medium befindet. Das aus der Küvette austretende Licht wird mit einem Lichtdetektor (Photomultiplier) ge­messen. Um den Einfluß von Fremdlicht auszuschalten, ist es vorteilhaft, dem Laser einen Chopper nachzuschalten und das am Photomultiplier empfangene Meßsignal in einem Lock-in Verstärker mit angeschlossenem Rechner und Schrei­ber am Ausgang des Photomultipliers zu verarbeiten.

    Abstract translation: 在该装置中,光从光源(优选He-Ne激光)照射到测试介质所在的测量单元中。 使用光检测器(光电倍增管)测量从比色皿出现的光。 为了消除外部光的影响,连接激光下游的斩光器并且在​​光电倍增器的输出端连接到计算机和记录器的锁定放大器处理在光电倍增器处接收的测量信号是有利的。

    DETECTION DEVICE
    7.
    发明公开
    DETECTION DEVICE 审中-公开

    公开(公告)号:EP3159677A4

    公开(公告)日:2018-02-21

    申请号:EP15809717

    申请日:2015-06-16

    Abstract: A detection device comprises a chip holder, a light source, a light-guide rod, a wavelength separation filter, and an optical sensor. Given the relationship between the angle of incidence and light intensity of fluorescence on a light reception surface of the optical sensor, the optical transmittance of the wavelength separation filter at the dominant wavelength of the rays of fluorescence incident on the light reception surface at a peak angle of incidence at which the light intensity is the highest is greater than the optical transmittance of the wavelength separation filter at the dominant wavelength of the rays of excitation light incident on the light reception surface at the peak angle of incidence and is higher than the optical transmittance of the wavelength separation filter at the dominant wavelength of the rays of fluorescence incident on the light reception surface at an angle of incidence of 0 DEG.

    DETECTION DEVICE
    8.
    发明公开
    DETECTION DEVICE 审中-公开
    检测装置

    公开(公告)号:EP3273226A1

    公开(公告)日:2018-01-24

    申请号:EP16764767.6

    申请日:2016-03-08

    Abstract: This detection device has a holder, light irradiation unit, angle adjustment unit, light receiving sensor, light receiving optical system, optical filter, and a control unit. The light receiving optical system guides light from a detection chip to the light receiving sensor. The optical filter is disposed in the light receiving optical system, blocks a part of plasmon scattered light, and passes, out of the light emitted from the detection chip, a part of the plasmon scattered light, and fluorescence emitted from a fluorescent material. The light receiving sensor detects the fluorescent light, and the part of the plasmon scattered light, which have been emitted from the detection chip and passed the optical filter. On the basis of the detection results of the plasmon scattered light, the control unit controls the angle adjustment unit, and adjusts the incident angle of the excitation light to a predetermined incident angle.

    Abstract translation: 该检测装置具有支架,光照射单元,角度调整单元,光接收传感器,光接收光学系统,滤光器和控制单元。 光接收光学系统将来自检测芯片的光引导至光接收传感器。 滤光器设置在光接收光学系统中,阻挡等离子体激元散射光的一部分,并且使从检测芯片发射的光中的部分等离子体激元散射光和从荧光材料发出的荧光通过。 光接收传感器检测从检测芯片发出并通过光学滤波器的荧光和部分等离子体激元散射光。 基于等离子体激元散射光的检测结果,控制单元控制角度调节单元,并且将激发光的入射角调节为预定入射角。

    LIQUID AND PLATE SENSORS FOR MICROPLATE INJECTOR SYSTEM
    9.
    发明公开
    LIQUID AND PLATE SENSORS FOR MICROPLATE INJECTOR SYSTEM 有权
    用于微孔注射系统的液体和板传感器

    公开(公告)号:EP3230719A1

    公开(公告)日:2017-10-18

    申请号:EP15868139.5

    申请日:2015-12-08

    Abstract: In a sample analyzing apparatus, an injector assembly injects a reagent onto a sample, and luminescent light from the sample is transmitted to a detector. The assembly may be movable toward and away from the sample. The assembly may include one or more needles that communicate with one or more reservoirs supplying reagent or other liquids. The assembly may include a light guide for communicating with the detector. A cartridge may be provided in which the assembly, one or more reservoirs, and one or more pumps are disposed. The cartridge and/or the apparatus may be configured for enabling rinsing or priming to be done outside the apparatus. The cartridge and/or the apparatus may include one or more types of sensors configured for detecting, for example, the presence of liquid or bubbles in one or more locations of the apparatus and/or the cartridge.

    Abstract translation: 在样品分析装置中,注射器组件将试剂注入到样品上,并且来自样品的发光被传送到检测器。 该组件可以朝向和远离样品移动。 该组件可以包括与供应试剂或其他液体的一个或多个储存器连通的一个或多个针。 该组件可以包括用于与检测器通信的光导。 可以提供盒,其中设置有组件,一个或多个储存器以及一个或多个泵。 盒和/或装置可以被构造成能够在装置外部进行冲洗或灌注。 盒和/或装置可以包括一种或多种类型的传感器,其被配置用于检测例如装置和/或盒的一个或多个位置中是否存在液体或气泡。

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