摘要:
The present invention is directed to a dispensing system for providing a preset small volume of liquid ≤ 200 µl into a filling area of a microfluidic sample carrier comprising at least one flow channel, the system including, inter alia, a liquid reservoir, a liquid pump connected to the liquid reservoir, at least one interface unit provided for each flow channel of the microfluidic sample carrier, wherein the liquid is provided to each flow channel by means of the respective interface unit, and at least one monitoring means adapted to monitor filling of said at least one flow channel of the microfluidic sample carrier, for monitoring the progress of liquid movement within said at least one flow channel along a flow direction of the liquid. Furthermore, the present invention relates to a respective microfluidic sample carrier sealing system and to a respective method of dispensing sealing liquid into a microfluidic sample carrier.
摘要:
A biosensor device for simultaneous multiple-analyte analysis by a plurality of biosensors dipped in single biosensor micro-chamber flooded with a functional liquid flowing to the biosensor micro-chambers from a fluidic circuit with no symmetry prerequisite comprising micro-valves operably associated to biosensor micro-chambers for selectively allowing the crossing of a functional liquid to the biosensor micro-chambers, a biosensor micro-chamber at a time, according to a pulsating flow mode so that the total flow rate can be greatly reduced and a predetermined amount of a pressured functional liquid is multiplexed to biosensor micro-chambers. Related methods are defined for such a biosensor device.
摘要:
The present invention refers to a liquid handling and/or distributing system (1) and method, wherein the system (1) is configured in order to control the supply of at least one liquid (2-1, 2-2, 2-3) into a plurality of assigned liquid targets (21, 22, 23), comprises a channel assembly (60) having an upstream receiving section (61), a downstream distributing section (62) and a single and common connection channel (63) fluidly connecting said receiving section (61) and said distributing section (62), wherein said receiving section (61) is configured in order to receive said at least one liquid (2-1, 2-2, 2-3) into said single and common connection channel (63), wherein said distributing section (62) (I) comprises discharge channels (62-1, 62-2, 62-3) branching at their upstream end from said single and common connection channel (63), assigned in one-to-one correspondence to said liquid targets (21, 22, 23) and configured in order to be fluidly connected or connectable at their downstream end to an assigned liquid target (21, 22, 23) and (II) is configured in order to distribute said at least one liquid (2-1, 2-2, 2-3) from said single and common connection channel (63) into a liquid target (21, 22, 23) via a respective assigned discharge channel (62-1, 62-2, 62-3). The system (1) further comprises a discharge valve unit (42) having a respective discharge valve (42-1, 42-2, 42-3) located within a respective assigned discharge channel (62-1, 62-2, 62-3) for controllably and selectively opening and closing the passage of said respective assigned discharge channel (62-1, 62-2, 62-3).
摘要:
A method for switching a high pressure fluid includes applying a fixed force between a planar surface of a rotor and a planar surface of a stator. The planar surface of the rotor includes a fluidic channel and the planar surface of the stator has a pair of ports to receive and provide the fluid. A control signal is applied to a linear actuator coupled to the rotor to generate a controllable force between the planar surfaces of the rotor and stator. The control signal is responsive to a rotational state of the rotor. The total force between the planar surfaces of the rotor and the stator is substantially equal to a sum of the fixed force and the controllable force. The method reduces the wear and extends the lifetime of components in a rotary shear seal valve.
摘要:
Automated sampling and reaction systems and methods of using the same are provided. The automated sampling and reaction system has a microreactor in fluidic communication with an external sampling valve. The external sampling valve is connected to a priming valve and can be configured to draw sample from a reactor or a reactor stream. The microreactor is connected to a reagent valve and an injection valve. The reagent valve can be configured to draw reagent from a reagent reservoir and discharge reagent to the microreactor to react with sample. The priming valve can be configured to draw wash from a wash reservoir and discharge wash to the external sampling valve to move sample from the external sampling valve to the microreactor. The injection valve is in fluidic communication with a column or detector and discharges the secondary sample into a solvent composition stream.
摘要:
In a gas analysis apparatus including analyzers that need ignition, such as FIDs, in order to make it possible to surely ignite the analyzers while downsizing the entire apparatus, the apparatus includes first and second analyzers 11 and 12 to accept a sample gas, a first gas line L1 provided with the first analyzer 11, a second gas line L2 provided with the second analyzer 12 and joined downstream of the first analyzer 11 in the first gas line L1. At least one of the first analyzer 11 and the second analyzer 12 is configured to cause pressure fluctuations in the gas line L1, L2 including the analyzer 11, 12 when analyzing the sample gas. A first backflow prevention mechanism 21 is disposed between another of the analyzers 12, 11 and a junction X of the gas lines L1 and L2. The first backflow prevention mechanism is configured to prevent a fluid from flowing backward from the one of the analyzers 11, 12 through the junction X toward the another of the analyzers 12, 11.