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1.发明公开
公开(公告)号：EP2269723A3
公开(公告)日：2012-01-25
申请号：EP10167543.7
申请日：2002-12-05
发明人： Cook, Ronald M. , Dill, Rand , Baltzley, Arnie
IPC分类号： B01J19/00
CPC分类号： G01N35/1002 , B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/0036 , B01J2219/00389 , B01J2219/00414 , B01J2219/00423 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00689 , B01J2219/00722 , B01L3/0203 , C40B40/06 , C40B60/14 , G01N35/1065 , Y10T436/11 , Y10T436/114165 , Y10T436/119163 , Y10T436/2575
摘要： Embodiments of the present invention are directed to an improved chemical synthesis apparatus for performing chemical synthesis such as nuclei acid synthesis in a plurality of reaction wells or cells in an efficient manner. The apparatus employs dispenser heads (16) that each include a cluster of nozzles (14) which are fluidicly coupled to a plurality of reagent sources (12) for dispensing different reagents through the single dispenser head. Because each dispenser head (16) is capable of dispensing a plurality of different reagents, the apparatus can perform simultaneous synthesis in a plurality of cells at a high throughput without complex and elaborate control of movement of the dispenser heads (16) relative to the cells.
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公开(公告)号：EP1697754B1
公开(公告)日：2010-06-30
申请号：EP04812649.4
申请日：2004-12-01
IPC分类号： G01N35/10
CPC分类号： G01N1/312 , B01L3/0203 , B01L2200/0605 , G01N35/1002 , Y10T436/2575
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公开(公告)号：EP2128502A2
公开(公告)日：2009-12-02
申请号：EP09155727.2
申请日：2009-03-20
申请人： Poulten & Graf Ltd
发明人： Hawkins, James
CPC分类号： F16K5/0492 , B01L3/0203 , B01L3/567 , B01L2200/0689
摘要： A stopcock (10) for use with a glass cane, comprising: a body (12) for attachment to one end of a glass cane, the body having a channel (22) therethrough which in use communicates with fluid in a glass cane when the body is attached to one end thereof; and a key (14) rotatably mounted in the channel (22), the key (14) being configured to allow fluid to flow through the channel (22) when in one orientation relative to the body (12) and to prevent fluid flowing through the channel (22) when in another orientation, characterized in that the key (14) and body (12) have interengageable profiles (32, 34) which are configured to retain the key (14) in the body (12) when interengaged.
摘要翻译： 一种用于玻璃手杖的旋塞（10），包括：主体（12），用于附接到玻璃手杖的一端，所述主体具有通道（22），所述通道在所述通道中与所述玻璃with中的流体连通， 身体附在一端; 以及可旋转地安装在所述通道（22）中的键（14），所述键（14）构造成当相对于所述主体（12）处于一个取向时允许流体流过所述通道（22），并且防止流体流过 所述通道（22）当处于另一方向时，其特征在于，所述钥匙（14）和主体（12）具有相互接合的轮廓（32,34），所述轮廓构造成当相互接合时将所述钥匙（14）保持在所述主体（12）中。
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公开(公告)号：EP1364710A3
公开(公告)日：2006-03-22
申请号：EP03010575.3
申请日：2003-05-12
发明人： Hughes, Kevin , Perreault, Mark
IPC分类号： B01L3/00
CPC分类号： B01L3/5025 , B01L3/0203 , B01L3/50853 , B01L2200/0642 , B01L2300/047 , B01L2300/0829 , B01L2300/0864 , B01L2300/18 , B01L2400/0442 , B01L2400/049 , Y10T436/2575
摘要： A self-aliquoting dispensing unit for use with a multi-receptacle storage unit is provided including a lower plate having a plurality of access ports therethrough, wherein at least one of the access ports is in fluid communication with a microtube, an upper plate releasably attached to the lower plate, the upper plate including a sample port for supplying a sample to the dispensing unit, and a sealing member for forming a reversible fluid tight connection between the storage unit and the upper plate. An assembly for dispensing a sample into a multi-receptacle storage unit and a method for dispensing a sample into a multi-receptacle storage unit are also provided.
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公开(公告)号：EP1461147A1
公开(公告)日：2004-09-29
申请号：EP02792328.3
申请日：2002-12-05
发明人： COOK, Ronald, M. , DILL, Rand , BALTZLEY, Arnie
IPC分类号： B01J19/00
CPC分类号： G01N35/1002 , B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/0036 , B01J2219/00389 , B01J2219/00414 , B01J2219/00423 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00689 , B01J2219/00722 , B01L3/0203 , C40B40/06 , C40B60/14 , G01N35/1065 , Y10T436/11 , Y10T436/114165 , Y10T436/119163 , Y10T436/2575
摘要： Embodiments of the present invention are directed to an improved chemical synthesis apparatus for performing chemical synthesis such as nuclei acid synthesis in a plurality of reaction wells or cells in an efficient manner. The apparatus employs dispenser heads (16) that each include a cluster of nozzles (14) which are fluidicly coupled to a plurality of reagent sources (12) for dispensing different reagents through the single dispenser head. Because each dispenser head (16) is capable of dispensing a plurality of different reagents, the apparatus can perform simultaneous synthesis in a plurality of cells at a high throughput without complex and elaborate control of movement of the dispenser heads (16) relative to the cells.
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公开(公告)号：EP0937502A3
公开(公告)日：2000-05-31
申请号：EP98660141.7
申请日：1998-12-15
申请人： WALLAC OY
发明人： Pietilä, Pekka , Kivelä, Petri
CPC分类号： B01L3/0203 , B01L99/00 , B01L2200/0684 , B01L2400/0409 , G01N35/028
摘要： A method for handling a microplate, in which liquid (22) is dosed into a sample well (21) and the liquid is removed and, if necessary, the sample wells are further washed and/or rinsed. According to the invention, the liquid to be dosed is dosed into the sample well (21) of the sample plate (10), after which the sample plate is centrifuged so that the centrifugal force is exerted towards the bottom of the sample well to remove air bubbles, and/or the sample plate is centrifuged so that the centrifugal force is exerted away from the bottom of the sample well to empty the sample plate. The device relating to the invention comprises a dosing device and at least one centrifuge (24). In dosing, a distributing valve (14) and a dosing nozzle (12) are usually needed, and where necessary, a vibrator device (32, 33) to bring the liquid (22) in the sample well (21) of the sample plate (10) into a motion. According to one embodiment, the vibrator device (33) comprises a needle (34) that is dipped into the liquid (22) in the sample well (21) of the sample plate (10), and by means of the vibration of the needle air bubbles can also be removed from the liquid.
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公开(公告)号：EP0180591B1
公开(公告)日：1989-01-25
申请号：EP85901444.1
申请日：1985-04-04
申请人： PROLIC S.A.
发明人： BÖHME, Eike , RUBENZER, Peter
IPC分类号： B01L3/02
CPC分类号： B01L3/0203 , Y10T137/86381
摘要： Dispensing device enabling to supply a liquid into the wells of a titration plate. In order to obtain an optimum dispensing quality, filling tubes (6) are provided from a distribution tube (5) first upwardly and, after a deviation zone (8), downwardly into a discharge zone (9).
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公开(公告)号：EP2142441B1
公开(公告)日：2013-03-06
申请号：EP08746417.8
申请日：2008-04-21
发明人： CERNOHOUS, Adam J.
CPC分类号： B65D47/18 , B01L3/0203 , B65D51/1616
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公开(公告)号：EP1697754A1
公开(公告)日：2006-09-06
申请号：EP04812649.4
申请日：2004-12-01
IPC分类号： G01N35/10
CPC分类号： G01N1/312 , B01L3/0203 , B01L2200/0605 , G01N35/1002 , Y10T436/2575
摘要： A fluid dispenser useful in methods and apparatuses for automated biological reaction systems including a barrel (408), a coupler (428), a piston (454) associated with the barrel (408), and a sealing surface that seals the inner diameter against fluid flow at the lower extent of the piston (454).
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公开(公告)号：EP1631388A2
公开(公告)日：2006-03-08
申请号：EP04755038.9
申请日：2004-06-09
申请人： Dako Denmark A/S
发明人： FALB, Peter , THAXTER, Charles, W., Sr. , CLARE, David , SACCO, Victor, Jr. , LEON, Scott , LUCIA, Shannon , RIOUX, Eric, R.
CPC分类号： B05B11/3032 , A61M5/162 , A61M5/16809 , A61M2205/071 , B01L3/0203 , B01L2200/0605 , B01L2400/0605 , B01L2400/0633 , B05B11/0043 , B05B11/0059 , F04B9/14 , F04B43/02 , G01F11/08 , G01N35/1002
摘要： This invention describes a method and apparatus for a dispenser assembly (1) suitable for dispensing reagent in an automatic system. In embodiments, the present invention may include a metering chamber (32) that accurately controls the amount of fluid dispensed. In other embodiments, the amount of fluid may be controlled by the action of a flexible diaphragm (33), which may be assembled into a cavity of a dispenser housing creating a metering chamber. In another embodiment, a volume created by a metering chamber may determine the volume of dispensed fluid. When a diaphragm is compressed from its free or uncompressed position (36) to an inverted or compressed position (37), it may substantially conform to the inner surface of the metering chamber. Fluid enters a metering chamber through an inlet unidirectional valve (34) and exits a metering chamber through an outlet unidirectional valve (25).
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