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    BONE MRI USING A B0 INHOMOGENITY MAP AND A SUBJECT MAGNETIC SUSCEPTIBILITY MAP
    1.
    发明公开
    BONE MRI USING A B0 INHOMOGENITY MAP AND A SUBJECT MAGNETIC SUSCEPTIBILITY MAP 审中-公开
    使用B0不均匀图和主题磁敏感图

    公开(公告)号：EP3308185A1

    公开(公告)日：2018-04-18

    申请号：EP16727205.3

    申请日：2016-06-07

    申请人： Koninklijke Philips N.V.

    发明人： BOERNERT, Peter ,  NEHRKE, Kay ,  EGGERS, Holger

    IPC分类号： G01R33/44 ,  G01R33/48 ,  G01R33/56 ,  G01R33/565 ,  A61B5/055

    CPC分类号： G01R33/4816 ,  A61B5/055 ,  A61N5/1039 ,  A61N5/1049 ,  A61N2005/1055 ,  G01R33/443 ,  G01R33/481 ,  G01R33/4812 ,  G01R33/4828 ,  G01R33/56 ,  G01R33/56536 ,  G01R33/56563

    摘要： The invention provides for a medical instrument (100, 500) comprising a magnetic resonance imaging system (102) for acquiring magnetic resonance data (142) from a subject (118) within an imaging zone (108). The magnetic resonance imaging system comprises: a main magnet (104) for generating a B0 magnetic field within the imaging zone; a memory (134, 136) containing machine executable instructions (160, 162, 164, 166) and pulse sequence commands (140); a processor (130) for controlling the medical instrument. Execution of the machine executable instructions causes the processor to: acquire (200) the magnetic resonance data by controlling the magnetic resonance imaging system with the pulse sequence commands; receive (202) a subject magnetic susceptibility map (144) of the subject; calculate (204) a B0 inhomogeneity map (146) from the magnetic resonance data; calculate (206) a subject B0 magnetic field perturbation (148) from the subject magnetic susceptibility map; calculate (208) a residual B0 magnetic field perturbation (150) by subtracting the subject B0 magnetic field perturbation from the B0 inhomogeneity map; and calculate (210) a bone map (152) from the residual B0 magnetic field perturbation.

    ZERO ECHO TIME MR IMAGING WITH SAMPLING OF K-SPACE CENTER
    2.
    发明公开
    ZERO ECHO TIME MR IMAGING WITH SAMPLING OF K-SPACE CENTER 审中-公开
    与扫描K空间中心NULL回波时间磁共振成像

    公开(公告)号：EP3100066A1

    公开(公告)日：2016-12-07

    申请号：EP15701509.0

    申请日：2015-01-21

    申请人： Koninklijke Philips N.V.

    发明人： SMINK, Jouke ,  HARVEY, Paul Royston

    IPC分类号： G01R33/48

    CPC分类号： G01R33/4826 ,  G01R33/4816

    摘要： The invention relates to a method of MR imaging of an object positioned in an examination volume of a MR device (1).It is an object of the invention to enable 'silent' ZTE imaging with sampling of k-space center. According to the invention, the object (10) is subjected to an imaging sequence of RF pulses (20) and switched magnetic field gradients (G), wherein an initial RF pulse (20) is radiated before setting a readout magnetic field gradient (G). An initial MR signal is acquired with the readout magnetic field gradient(G) ramping up after a delay after the initial RF pulse (20). Thereafter, the magnetic field gradient (G) remains switched on and the readout direction is gradually varied. Further RF pulses(22) are radiated in the presence of the readout magnetic field gradient(G) and further MR signal are acquired like in conventional ZTE imaging. Finally, a MR image is reconstructed from the acquired MR signals. Moreover, the invention relates to a MR device and to a computer program for a MR device.

    Method and assembly for correcting a relaxation map for medical imaging applications
    5.
    发明公开
    Method and assembly for correcting a relaxation map for medical imaging applications 审中-公开
    方法和装置用于校正Relaxationskarte用于医疗成像应用

    公开(公告)号：EP2221627A1

    公开(公告)日：2010-08-25

    申请号：EP09153351.3

    申请日：2009-02-20

    申请人： IBBT vzw ,  Ghent University

    发明人： Keereman, Vincent ,  Vandenberghe, Stefaan ,  De Deene, Yves

    IPC分类号： G01R33/50 ,  G01R33/565

    CPC分类号： G01R33/4808 ,  G01R33/481 ,  G01R33/4816 ,  G01R33/4828 ,  G01R33/50 ,  G01R33/5608 ,  G01R33/5615

    摘要： The present invention is related to a method for correcting a relaxation map of a scanned object comprising a plurality of structure and/or tissue types. The proposed method comprises the steps of :
    - deriving a first estimate of a relaxation map of a scanned object from at least two scans of said object acquired with a medical imaging modality by means of a sequence of pulses adapted for distinguishing between the various types of a plurality of structure and/or tissue types of said object,
    - obtaining information on the content of voxels present in the first estimate of the relaxation map,
    - obtaining a corrected estimate of the relaxation map by combining the information on the content with the first estimate of the relaxation.

    摘要翻译： 本发明涉及一种方法，用于校正被扫描对象包括结构和/或组织类型的多个松弛地图。 所提出的方法包括以下步骤： - 通过脉冲angepasst的序列的方式导出从与医疗成像模态采集所述对象的至少两个扫描被扫描对象的松弛地图的第一估计为各种类型的区分 结构和/或组织类型所述对象的，一个多元化 - 获取有关存在于所述松弛地图的第一估计的体素的内容的信息， - 通过对所述内容与所述第一组合信息获取松弛地图的校正估计 松弛的估​​计。

    Methods suitable for measuring capillary pressure and relative permeability curves of porous rocks
    6.
    发明公开
    Methods suitable for measuring capillary pressure and relative permeability curves of porous rocks 审中-公开
    一种用于测量毛细管压力曲线和描述多孔岩石的相对导磁率的方法

    公开(公告)号：EP2006702A2

    公开(公告)日：2008-12-24

    申请号：EP08157890.8

    申请日：2008-06-09

    申请人： University of New Brunswick

    发明人： Balcom, Bruce J. ,  Quan, Chen

    IPC分类号： G01R33/44 ,  G01R33/54 ,  G01V3/32

    CPC分类号： G01R33/44 ,  G01N15/082 ,  G01N24/081 ,  G01R33/4816 ,  G01V3/32 ,  Y02A90/344

    摘要： Single-shot methods suitable for determining capillary pressure and relative permeability curves are proposed. For steady-state gas flow, with stationary water or oil remaining in a porous rock core and the outflow boundary condition (capillary pressure is zero) is maintained by washing the outlet face of the core with the stationary phase, the gas pressure distribution, P(x), is determined by SPRITE (Single-Point Ramped Imaging with T 1 Enhancement) MRI (Magnetic Resonance Imaging) spin density imaging of flowing gas, since the spin density of gas is directly proportional to the pressure of the gas phase. Water or oil saturation distribution, S(x), at the present of steady-state flowing gas, is measured with MRI. The combination of P(x) and S(x) yields a capillary pressure curve, P c (S) and relative permeability curve of flowing gas phase, K rg (S) can be determined with differential form of Darcy's law and ideal gas equations for gas flowing at steady-state. Some embodiments include the steps of providing a porous rock core having a length, an inlet face, and an outlet face; saturating the porous rock core with a first fluid; displacing the first fluid by applying a second fluid to the inlet face of the porous rock core; washing the outlet face of the porous rock core with said second fluid so as to maintain an outflow boundary condition; determining that a substantially steady-state condition has been reached whereat the fluid saturation distribution and pressure distribution along the length of the core do not substantially change with time; performing a single-shot measurement of at least one of a fluid saturation distribution measurement of the porous rock core and a pressure distribution measurement of the porous rock core; and determining a property of the porous rock core by using the single-shot measurement.

    摘要翻译： 适合确定性采矿毛细管压力和相对渗透率曲线的单次方法提议。 对于稳态气流，用静止的水或油中的多孔岩石芯和流出边界条件的剩余（毛细管压力为零），通过与固定相，气体压力分布，P洗涤芯的出口面保持 （x）是由确定性SPRITE（单点积分给成像与T1增强）MRI（磁共振成像）流动的气体的自旋密度成像开采中，由于气体的自旋密度是正比于气相的压力。 水或油饱和度分布，S（x）时，在本的稳态流动的气体，被测量的MRI。 P的组合（x）和S（x）的产生的毛细管压力曲线，P C（S）和流动的气体相，K RG（S）的相对渗透率曲线可以是确定与达西定律的微分形式和理想气体方程开采 用于气体流动的在稳定状态。 一些实施方式包括：提供具有在入口面的长度的多孔岩石的芯的步骤，并在出口面; 饱和与第一流体的多孔岩石芯; 通过将第二流体在多孔岩石芯的入口面移动第一流体; 洗涤该多孔岩石芯与所述第二流体，以便在流出边界条件，以保持的出口面; 确定性开采做的基本上稳态条件已在该处沿核心基本上不随时间而变化的长度的流体饱和度分布和压力分布达到; 执行所述多孔岩石芯和多孔岩石芯的压力分布测量的流体饱和度分布测量中的至少一个的一个单次测量; 和确定性采矿通过使用单次测量的多孔岩石芯的特性。

    Method for improving the resolution of solid-state NMR multiple-pulse imaging systems
    8.
    发明公开
    Method for improving the resolution of solid-state NMR multiple-pulse imaging systems 失效
    一种用于使用核磁共振的多个脉冲改善成像的装置中的固体的解析方法。

    公开(公告)号：EP0563650A1

    公开(公告)日：1993-10-06

    申请号：EP93104048.9

    申请日：1993-03-12

    申请人： BRUKER INSTRUMENTS, INC.

    发明人： Cory, David G.,Dr.

    IPC分类号： G01R33/48 ,  G01R33/56

    CPC分类号： G01R33/4816

    摘要： In an NMR solid-state imaging experiment, a pulsed gradient (gradient) is interleaved between subcycles (100, 102, 104, 106 and 108, 110, 112, 114) of a line-narrowing RF pulse sequence (RF) in such a manner that the RF and gradient fields do not overlap in time, the subcycles of RF modulation which occur between gradient pulses (100, 102, 104, 106 and 108, 110, 112, 114) are either cyclic or anti-cyclic and symmetric.
    The line-narrowing pulse sequence can be broken into subcycles (100, 102, 104, 106 and 108, 110, 112, 114), each of which is dipolar decoupling to at least a zero-order approximation. The gradient pulses are intercalated between a selected set of the subcycles which are symmetric. In this manner the prior art zero-order decoupling of the line narrowing interaction and the gradient interaction is extended to include the zero order and all odd order terms in the Magnus expansion of the average dipolar Hamiltonian. If the selected subcycle is dipolar decoupling to second order, then the gradient will also be decoupled to second order.

    摘要翻译： 在NMR固态成像实验中，一个脉冲梯度（梯度）是在寻求一个线窄化RF脉冲序列（RF）的子周期（100，102，104，106和108，110，112，114）之间的交织 方式DASS死RF和梯度场在时间上不重叠，RF调制的梯度脉冲（100，102，104，106和108，110，112，114）之间发生的子周期或者是环状或抗环和对称的。 线窄化脉冲序列可以被分成子周期（100，102，104，106和108，110，112，114），每个的所有这一切是偶极去耦至少一个零阶近似。 梯度脉冲被选定的一组哪些是对称的子周期的间插入。 以这种方式，线变窄相互作用和梯度相互作用的现有技术的零级解耦被扩展成包括零阶和在平均偶极哈密顿的马格努斯膨胀所有奇数阶项。 如果所选择的子周期是偶极去耦到第二阶，然后梯度从而将被去耦，以第二顺序。

    Verfahren zur mehrdimensionalen Messung von magnetischer Resonanz in definierten kleinen Volumenbereichen einer Festkörper-Probe
    10.
    发明公开
    Verfahren zur mehrdimensionalen Messung von magnetischer Resonanz in definierten kleinen Volumenbereichen einer Festkörper-Probe 失效
    一种用于在固态样品的限定体积小区域的磁共振的多维测量方法。

    公开(公告)号：EP0407879A2

    公开(公告)日：1991-01-16

    申请号：EP90112754.8

    申请日：1990-07-04

    申请人： Bruker Medizintechnik GmbH

    发明人： Kimmich, Rainer, Prof.-Dr. ,  Rommel, Eberhard, Dr. Dipl.-Ing. ,  Hafner, Siegfried, Dipl.-Phys.

    IPC分类号： G01R33/48

    CPC分类号： G01R33/4816

    摘要： Ein Verfahren dient zur mehrdimensionalen Messung von magneti­scher Resonanz in definierten kleinen Volumenbereichen einer Festkörper-Probe. Die Probe wird in einem konstanten, homogenen Magnetfeld angeordnet und in vorbestimmter Weise mit einer Folge von Hochfrequenz-Impulsen (11, 12, 13, 17, 18, 19) bestrahlt sowie einer Folge von Gradienten-Magnetfeld-Impulsen (14 bis 16) ausgesetzt. Dies geschieht derart, daß die zu messende Magnetisierung der Spins für eine Zeitdauer aufrecht­erhalten wird, die länger als eine Abschaltdauer der Gradienten-­Magnetfeld-Impulse (14 bis 16) ist. Zunächst wird in einem ersten Zeitintervall (τ₁) die Magnetisierung nur einer Scheibe der Probe in eine um 90° gekippte Transversalmagnetisierung überführt. Alsdann werden in einem zweiten Zeitintervall (τ₂) volumenselektive Gradienten-Magnetfeld-Impulse (15, 16) einge­strahlt. In einem dritten Zeitintervall (τ₄), während des Andauerns der volumenselektiven Gradienten-Magnetfeld-Impulse (15, 16) werden Hochfrequenz-Impulse (17 bis 19) auf die Probe eingestrahlt, welche die zu messende Transversalmagnetisierung im Volumenbereich in einen Multipol-Zustand überführen, der für die volumenselektiven Gradienten-Magnetfeld-Impulse (15, 16) unempfindlich ist und bis über den Zeitpunkt deren Abschal­tens andauert. Schließlich wird in einem vierten Zeitintervall τ₃der Multipol-Zustand wieder in eine Transversalmagneti­sierung rückgeführt und diese als Signal (20) ausgelesen.

    摘要翻译： 在该方法中，将样品在恒定均匀的磁场与高频脉冲（11，12，13，17，18，19）的序列排列并照射以预定的方式，并暴露于梯度磁场的序列 脉冲（14至16）。 这在检查的方式进行确实的自旋所有这些将被测量的磁化被保持的时间超过所有长这是梯度磁场脉冲的关闭周期（14至16）。 首先，只有样品的切片的磁化被改变为通过在第一时间间隔90°（TAU 1）倾斜的横向磁化。 然后，体积选择性倾斜磁场脉冲（15，16）中的第二时间间隔（-τ2）被辐射英寸 在第三时间间隔（TAU 4），在体积选择性梯度磁场脉冲（15，16）的期间，高频脉冲（17至19）被辐射到其上改变横向磁化以在待测量的样品 卷区域成一个多极状态所有这些是不敏感的体积选择性倾斜磁场脉冲（15，16）和最后一个过去的时间当它们被关断。最后，将多极的状态变回至横向 磁化，这被读出作为在第四时间间隔（TAU 3）信号（20）。 ... ...