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    Inhibitors of slow reacting substance of anaphylaxis
    1.
    发明公开
    Inhibitors of slow reacting substance of anaphylaxis 失效
    Inhibitoren der langsam reactierenden anaphylaktischen Substanz。

    公开(公告)号：EP0169033A2

    公开(公告)日：1986-01-22

    申请号：EP85304967.4

    申请日：1985-07-11

    申请人： SCHERING CORPORATION

    发明人： Saksena, Anil Kumar ,  Wong, Jesse Kwok-Keung ,  Mangiaracina, Pietro

    IPC分类号： C07C59/60 ,  C07C327/18 ,  C07C327/36 ,  C07C69/734 ,  C07C43/178 ,  C07C229/30 ,  C07D309/00

    CPC分类号： C07C59/60 ,  A61K31/19 ,  C07C33/042 ,  C07C45/515 ,  C07C47/222 ,  C07C323/00

    摘要： Novel compounds (and their pharmaceutically acceptable salts) and compositions which inhibit slow reacting substance of anaphylaxis in mammals are disclosed, together with methods for preparing said compounds and compositions and methods for their use for treating psoriasis, allergic reactions and inflammation and for reducing the severity of myocardial infarction resulting from heart attack.
    The novel compounds are of the formula A
    wherein Z and Z 1 are W-X or Y where W is 0, S, SO or S0 2 ; T is 7-15 alkyl; X is a 2-12 C divalent hydrocarbon group which may be substituted with the group -NHR a ; Y is 1-12 C alkylene; where T, X and Y can each contain 1-3 non-cumulative double or triple bonds; U is -CH 2 CH 2 -, -CH=CH-or -C≡C-; V is 1-4 C alkylene or a direct bond; R 2 and R 3 are hydrogen, CH 2 OR c , CHO, 2-tetrazolyl, CORd or S0 3 H, at least one of R 2 and R 3 being 2-tetrazolyl or carboxyl; and
    R is hydrogen or, where Z and Z 1 are both W-X, R can also be straight or branched chain alkyl having from 1 to 6 carbon atoms, or, where Z and Z 1 are both Y, R can also be hydroxy or fluorine or can be combined with Z and with the mutually bonded carbon atom to form a C-Z double bond or a cyclopropane ring.

    摘要翻译： 公开了抑制哺乳动物过敏反应缓慢反应物质的新型化合物（及其药学上可接受的盐）和组合物，以及用于制备所述化合物的方法及其用于治疗牛皮癣，过敏反应和炎症以及降低严重程度的组合物和方法 的心肌梗死引起的心肌梗死。 所述新化合物具有式A 其中Z和Z 1是W-X或Y，其中W是O，S，SO或SO 2; T为7-15烷基; X是可以被-NHR a基团取代的2-12个C 2价烃基; Y为1-12个C亚烷基; 其中T，X和Y各自可以含有1-3个非累积的双重或三重键; U是-CH 2 CH 2 - ， - CH = CH-或-C元素C-; V是1-4C亚烷基或直接键; R 2和R 3是氢，CH 2 OR c，CHO，2-四唑基，COR d或SO 3 H，R 2和R 3中的至少一个是2-四唑基或羧基; 并且R是氢，或者Z和Z 1都​​是WX，R也可以是具有1至6个碳原子的支链或支链烷基，或者Z和Z 1均为Y，R也可以是 羟基或氟，或者可以与Z和相互键合的碳原子结合形成CZ双键或环丙烷环。

    MATERIAU D'ELECTRODE POUR BATTERIE ORGANIQUE COMPRENANT DES DERIVES DE L'ACIDE BENZENE-BISDITHIOÏQUE
    3.
    发明公开
    MATERIAU D'ELECTRODE POUR BATTERIE ORGANIQUE COMPRENANT DES DERIVES DE L'ACIDE BENZENE-BISDITHIOÏQUE 有权
    材料FÜREINE ELEKTRODE EINER ORGANISCHEN BATTERIE MIT BENZOL-BIS（DITHIO）SÄURE-DERIVATEN

    公开(公告)号：EP3063127A1

    公开(公告)日：2016-09-07

    申请号：EP14809519.3

    申请日：2014-10-29

    申请人： Commissariat à l'Energie Atomique et aux Energies Alternatives

    发明人： GUTEL, Thibaut ,  DUBOIS, Lionel ,  IORDACHE, Adriana

    IPC分类号： C07C327/18 ,  C25B11/04 ,  H01L51/00

    CPC分类号： H01M4/137 ,  C07C327/18 ,  C09D5/4476 ,  C25D13/16 ,  H01B1/122 ,  H01M4/0402 ,  H01M4/0404 ,  H01M4/0411 ,  H01M4/0466 ,  H01M4/1399 ,  H01M4/60 ,  H01M4/602 ,  H01M4/608 ,  H01M4/623 ,  H01M4/625 ,  H01M10/052 ,  H01M10/0525 ,  H01M10/054

    摘要： The present invention concerns the use, as an active electrode material, of compounds comprising at least one entity of formula (I): in which the phenyl group is substituted with one to four identical or different substituent(s) R, chosen from a hydrogen atom, a halogen atom chosen from fluorine, chlorine, bromine or iodine, a -C(=S)-S
    - C+ group, an -O-C+ group, an -S-C+ group, C+ being an alkali cation chosen from Li+, Na+ and K+, a (C
    1 -C
    12 ) alkyl radical, a (C
    2 -C
    12 ) alkenyl radical, a (C
    6 -C
    14 ) aryl or heteroaryl radical; or two vicinal substituents R that can, if appropriate, be linked to each other to together form a 3- to 7-membered ring optionally including another heteroatom chosen from N, O or S; in the base or salt form; and the tautomeric forms of same. It also concerns an electrode material, an electrode and a lithium, sodium or potassium secondary battery, obtained from these compounds.

    摘要翻译： 本发明涉及使用包含至少一个式（I）的实体的化合物作为活性电极材料：其中苯基被一至四个相同或不同的取代基R取代，所述取代基选自氢 原子，选自氟，氯，溴或碘的卤素原子，-C（= S）-S-C +基，-O-C +基，-S-C +基，C +是选自Li + ，（C 1 -C 12）烷基，（C 2 -C 12）烯基，（C 6 -C 14）芳基或杂芳基; 或两个连位取代基R，如果合适，它们可以彼此连接在一起形成任选地包含选自N，O或S的另外的杂原子的3-至7-元环; 以碱或盐的形式; 和互变异构形式相同。 它还涉及从这些化合物获得的电极材料，电极和锂，钠或钾二次电池。