摘要:
This invention encompasses a method for the treatment or prevention of prostaglandin mediated diseases comprising administering to a mammalian patient a compound of formula (I) in an amount that is effective to treat or prevent said prostaglandin mediated disease. Novel compounds are also disclosed.
摘要:
A process for producing a polyhydroperoxy aromatic compound by oxidation of an aromatic hydrocarbon, e.g., 4,4'-diisopropylbiphenyl and 4,4'-diisopropylnaphthalene, with molecular oxygen is disclosed, in which the oxidation is carried out in the presence of a metal ion selected from cobalt, nickel, zinc and lead ions. Even in using a reaction apparatus made of an iron-containing metal generally employed in industry, a high conversion of secondary alkyl groups can be reached, and the desired polyhydroperoxy aromatic compound can be obtained in a high yield.
摘要:
A process for producing a polyhydroperoxy aromatic compound by oxidation of an aromatic hydrocarbon, e.g., 4,4'-diisopropylbiphenyl and 4,4'-diisopropylnaphthalene, with molecular oxygen is disclosed, in which the oxidation is carried out in the presence of a metal ion selected from cobalt, nickel, zinc and lead ions. Even in using a reaction apparatus made of an iron-containing metal generally employed in industry, a high conversion of secondary alkyl groups can be reached, and the desired polyhydroperoxy aromatic compound can be obtained in a high yield.
摘要:
A process for oxidizing a liquid component with an oxygen-containing gas, characterized in that the oxidation reaction is performed under a condition comprising an agitator power per unit volume of 10.0 to 500 kg . m/sec/m3.
摘要:
A process for producing hydroperoxides by oxidizing a hydrocarbon with an oxygen-containing gas in the presence of a specified compound to selectively convert the hydrocarbon into a corresponding hydroperoxide. The specified compounds are those capable of trapping free radicals, and preferred examples thereof include oxygen, nitrogen, phosphorus, sulfur, carbon and silicon radicals, and compounds capable of forming such radicals in a reaction system. This process is applicable to the oxidation of hydrocarbons including arylalkylhydrocarbons such as cumene, cymene, m-diisopropylbenzene, p-diisopropylbenzene, 1,3,5-triisopropylbenzene, isopropylnaphthalene, diisopropylnaphthalene, isopropylbiphenyl and diisopropylbiphenyl.