公开(公告)号：EP0129995A3

公开(公告)日：1985-06-12

申请号：EP84303752

申请日：1984-06-04

申请人： AECI LIMITED

发明人： Stiff, Anthony John

IPC分类号： C07C76/04 ,  C07C79/18 ,  C07C79/343

CPC分类号： C07C201/02 ,  C07C203/04

摘要： The invention concerns a process for the preparation of nitric acid esters of organic hydroxy compounds by reacting an organic hydroxy compound with nitric acid in the presence of sulphuric acid and in a solvent, followed by separating off the spent acid, substantially neutralizing the residual acidity of the organic solution, and removing solvent to leave the organic nitrate. From 95% to 220% of the stoichiometric requirement of nitric acid for complete nitration is used. The mole ratio of water to sulphuric acid at the end ofthe reaction is from 0,2:1 to 2,5:1. From 200 to 2000 ml of solvent per mole of hydroxy group is present. Yields of at least 92% are obtained. The invention is particularly suitable for the preparation of alkyl nitrates, alkylene or polyalkylene glycol, monoalkyl ether mononitrates, alkylene or polyalkylene glycol dinitrates, diol nitrates, nitrates containing homocyclic or heterocyclic rings, or nitrates derived from polyols.