公开(公告)号：EP3357920A1

公开(公告)日：2018-08-08

申请号：EP17196453.9

申请日：2013-05-16

申请人： Exigence Technologies Inc.

发明人： LIU, Song

IPC分类号： C07D403/12 ,  A01N43/50 ,  A01N43/647 ,  A01P1/00 ,  C07D233/72 ,  C07D233/82 ,  A01N33/12 ,  A01N35/02 ,  A01N59/00

CPC分类号： C07D403/12 ,  A01N33/12 ,  A01N35/02 ,  A01N43/50 ,  A01N43/647 ,  C07D233/72 ,  C07D233/82 ,  C07D401/12 ,  C07D403/14 ,  C07F9/6506 ,  Y10T442/30 ,  Y10T442/40 ,  Y10T442/60 ,  A01N59/00

摘要： Biocidally active cationic analogs of N-halamine having two biocidally active groups covalently bonded together in a single molecule and having general Formula (I). Compounds of Formula (I), and precursurs thereof, can be in solution form immobilized onto a substrate via physical coating or covalent chemical bonding to functionalize surfaces or added into materials as additives so as to render them biocidal. The biocidal solutions and substrates comprising the compounds or precursors of the present invention can then be used to inactivate pathogenic microorganisms. N-halamine-L-QUAT (I) wherein: the N-halamine may be a cyclic or acyclic N-halamine; L is C 1 -C 6 alkyl, cyclic aromatic or nonaromatic ring, ether, ketone or any other organic linking structures, and QUAT has general formula (II):

公开(公告)号：EP2341777B1

公开(公告)日：2015-01-21

申请号：EP09825372.7

申请日：2009-11-04

申请人： NovaBay Pharmaceuticals, Inc.

发明人： JAIN, Rakesh, K. ,  LOW, Eddy ,  FRANCAVILLA, Charles ,  SHIAU, Timothy P. ,  KIM, Bum ,  NAIR, Satheesh, K.

IPC分类号： A01N43/76 ,  A61K31/42 ,  A61K31/415 ,  C07D233/80 ,  C07D233/82 ,  C07D263/20 ,  C07D263/26 ,  C07D471/10 ,  C07D498/10

CPC分类号： A01N43/76 ,  A01N35/02 ,  A01N43/90 ,  A01N59/00 ,  A61K31/415 ,  A61K31/42 ,  C07D233/80 ,  C07D233/82 ,  C07D263/20 ,  C07D263/26 ,  C07D471/10 ,  C07D498/10

公开(公告)号：EP2663315A4

公开(公告)日：2014-06-25

申请号：EP11855570

申请日：2011-10-11

申请人： UNIV AUBURN

发明人： WORLEY SHELBY D ,  BROUGHTON ROYALL M ,  KOCER HASAN B ,  CERKEZ IDRIS

IPC分类号： A61K31/785 ,  A01N43/50 ,  C03C17/32 ,  C07D233/76 ,  C07D233/82 ,  C08F8/20 ,  C08F220/60

CPC分类号： C08F8/20 ,  A01N43/50 ,  A01N59/00 ,  B32B9/00 ,  C03C17/32 ,  C07D233/76 ,  C07D233/82 ,  Y10T428/1352 ,  Y10T428/31645 ,  Y10T428/31667 ,  Y10T428/31855 ,  Y10T428/3188 ,  Y10T428/31909 ,  C08F220/60

公开(公告)号：EP1250049A1

公开(公告)日：2002-10-23

申请号：EP01942511.5

申请日：2001-01-17

申请人： ALBEMARLE CORPORATION

发明人： ELNAGAR, Hassan, Y. ,  HOWARTH, Jonathan, N. ,  PETERS, Bruce, C. ,  SPIELMAN, Edgar, E., Jr. ,  THOMAS, Dustin, H.

IPC分类号： A01N59/00 ,  C07D233/82

CPC分类号： C07D233/82 ,  A01N59/00 ,  Y10S514/951 ,  A01N25/34 ,  A01N25/12 ,  A01N2300/00

摘要： Among the enhanced properties of the 1,3-dibromo-5,5-dimethylhydantoins described are their larger average particle sizes, their compactibility even though devoid of a binder, their excellent free-flowing and low-dust properties, and their more appealing aesthetic qualities, as compared to previously known 1,3-dibromo-5,5-dimethylhydantoins. These novel 1,3-dibromo-5,5-dimethyl-hydantoins can be produced, for example, by concurrently feeding (i) an aqueous solution or slurry formed from an inorganic base and 5,5-dimethylhydantoin, and (ii) a brominating agent, in proportions such that each nitrogen atom is substituted by a bromine atom, thereby forming product which precipitates in an aqueous reaction mixture. The pH of the reaction mixture is maintained in the range of 5.5 to 8.5.

公开(公告)号：EP0403159B1

公开(公告)日：2000-03-01

申请号：EP90306204.0

申请日：1990-06-07

申请人： SMITHKLINE BEECHAM CORPORATION

发明人： Finkelstein, Joseph Alan ,  Keenan, Richard McCulloch ,  Weinstock, Joseph

IPC分类号： C07D233/58 ,  C07D233/70 ,  C07D233/82 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  A61K31/415

CPC分类号： C07D233/64 ,  C07D401/06 ,  C07D405/06 ,  C07D409/06 ,  C07D409/14

公开(公告)号：EP2977370B1

公开(公告)日：2019-03-20

申请号：EP13878784.1

申请日：2013-11-15

申请人： Nippoh Chemicals Co., Ltd

发明人： FUJIWARA, Naoki ,  TAKAHASHI, Keisuke

IPC分类号： C07D233/82 ,  C07D233/72

公开(公告)号：EP2977370A1

公开(公告)日：2016-01-27

申请号：EP13878784.1

申请日：2013-11-15

申请人： Nippoh Chemicals Co., Ltd

发明人： FUJIWARA, Naoki ,  TAKAHASHI, Keisuke

IPC分类号： C07D233/82

CPC分类号： C07D233/82 ,  C07D233/72

摘要： A production method of the present invention is a method for producing a halohydantoin compound in which method a composition including a halohydantoin compound and an impurity is treated, the method including the step of adding the composition to a mixed solvent of water and an organic solvent and washing the composition.

摘要翻译： 本发明的制造方法是一种卤代乙内酰脲化合物的制造方法，其中处理包含卤代乙内酰脲化合物和杂质的组合物的方法包括以下步骤的方法：将组合物加入到水和有机溶剂的混合溶剂中， 洗涤组合物。

公开(公告)号：EP2921483A1

公开(公告)日：2015-09-23

申请号：EP15154215.6

申请日：2006-08-30

申请人： Nippoh Chemicals Co., Ltd

发明人： Inoue, Kazuhisa ,  Hanamaru, Yukihiko ,  Miyazawa, Takaaki

IPC分类号： C07D233/82

CPC分类号： C07D233/82

摘要： The present invention provides a means which can inhibit release of I 2 in storage of 1, 3-diiodohydantoin compound, and thereby solve decrease in purity of the compound and various problems caused by I 2 .
The present invention provides a storage method for 1,3-diiodohydantoin compounds comprising a step to store a 1,3-diiodohydantoin compound under a temperature condition of 15 ºC or lower.

摘要翻译： 本发明提供一种能够抑制1,3-二碘乙内酰脲化合物的储存中I2的释放，从而解决化合物的纯度降低和由I2引起的各种问题的手段。 本发明提供一种1,3-二碘乙内酰脲化合物的保存方法，其包括在15℃以下的温度条件下保存1,3-二碘乙内酰脲化合物的工序。

公开(公告)号：EP1939184B1

公开(公告)日：2013-06-05

申请号：EP06797085.5

申请日：2006-08-30

申请人： Nippoh Chemicals Co., Ltd

发明人： INOUE, Kazuhisa ,  HANAMURA, Yukihiko ,  MIYAZAWA, Takaaki

IPC分类号： C07D233/82

CPC分类号： C07D233/82

公开(公告)号：EP2522661A1

公开(公告)日：2012-11-14

申请号：EP12180061.9

申请日：2006-08-30

申请人： Nippoh Chemicals Co., Ltd

发明人： Inoue, Kazuhisa ,  Hanamura, Yukihiko ,  Miyazawa, Takaaki

IPC分类号： C07D233/82

CPC分类号： C07D233/82

摘要： The present invention provides a means which can inhibit release of I 2 in production or storage of 1, 3-diiodohydantoin compound, and thereby solve decrease in purity of the compound and various problems caused by I 2 .
The present invention provides a production method for 1,3-diiodohydantoin compound comprising a step to prepare a wet body containing a 1,3-diiodohydantoin compound, and (1) a step to dry the wet body by contacting the wet body with heated gas or (2) a step to lyophilize the wet body, a storage method for 1, 3-diiodohydantoin compound comprising a step to store a 1,3-diiodohydantoin compound under a temperature condition of 15 °C or lower, and a 1,3-diiodohydantoin compound wherein content of released I 2 is 1% by mass or less.

摘要翻译： 本发明提供一种能够抑制1,3-二碘乙内酰脲化合物的制造或保存中的I 2的释放，从而解决化合物的纯度降低和由I 2引起的各种问题的手段。 本发明提供1,3-二碘乙内酰脲化合物的制造方法，其包括：制备含有1,3-二碘乙内酰脲化合物的湿体的步骤，和（1）通过使湿体与加热气体接触来干燥湿体的步骤 或（2）冷冻干燥湿体的步骤，1,3-二碘乙内酰脲化合物的保存方法，该方法包括在15℃以下的温度条件下保存1,3-二碘乙内酰脲化合物的工序和1,3-二碘乙内酰脲化合物 - 二碘海因化合物，其中释放的I2的含量为1质量％或更少。