专利检索 ipc:"C12N09/68" 第 1 页

1.

发明公开
Enzyme-protein conjugate, process for its preparation and pharmaceutical use thereof 失效
标题翻译：酶 - 蛋白质结合体，其制备方法及药物用途

公开(公告)号：EP0155388A3

公开(公告)日：1986-12-10

申请号：EP84115346

申请日：1984-12-13

申请人： BEECHAM GROUP PLC

发明人： Smith, Richard Anthony Godwin

IPC分类号： A61K37/54 , A61K37/547 , C12N09/50 , C12N09/68 , C12N09/72 , C12N11/06 , C12N11/02 , C07D213/70

CPC分类号： C07D213/71 , C12N11/06

摘要： A derivative of a fibrinolytic enzyme in which the catalytic site on the enzyme which is responsible for fibrinolytic activity is blocked by human protein attached thereto by way of a reversible linking group.

2.

发明公开
Enzyme-protein conjugate, process for its preparation and pharmaceutical composition 失效
标题翻译：酶 - 蛋白质结合体，其制备方法和药物组合物

公开(公告)号：EP0152736A3

公开(公告)日：1986-12-10

申请号：EP85100084

申请日：1985-01-04

申请人： BEECHAM GROUP PLC

发明人： Ferres, Harry , Smith, Richard Anthony Godwin , Garman, Andrew John

IPC分类号： A61K37/54 , A61K37/47 , C12N11/06 , C12N09/50 , C12N09/68 , C12N09/72 , A61K39/44

CPC分类号： C12N9/6456 , A61K38/00 , A61K47/6815 , C12N11/02 , Y10S530/812

摘要： A fibrinolytically active protein conjugate comprising at least one optionally blocked fibrinolytic enzyme linked by way of a site other than the catalytic site responsible for fibrinolytic activity to at least one human protein. Processes from making the conjugates and pharmaceutical compositions containing them are also described.