公开(公告)号：EP2660573A2

公开(公告)日：2013-11-06

申请号：EP13002381.5

申请日：2013-05-03

Applicant: Morpho Detection, Inc.

Inventor： Vignesh, Thirukazhukundram Subrahmaniam ,  Sutherland, William Scott ,  Lee, Young Kyo ,  Dasaratha, Sridhar Venkataraman

IPC: G01J3/28 ,  G01J3/457 ,  G06F19/00

CPC classification number: G01J3/28 ,  F04C2270/041 ,  G01J3/457 ,  G01J2003/2833 ,  G01N21/65 ,  G01N2021/0118 ,  G01N2201/0221 ,  G01N2201/1293 ,  G06F19/703

Abstract: A spectrometer for identifying a mixture is provided. The spectrometer includes a detector configured to generate a signal based on an interaction of light with a sample of the mixture, and a memory device having a library and a correlation matrix stored therein, wherein the library includes a plurality of spectra, each spectrum associated with a respective compound, and wherein the correlation matrix includes a correlation between each possible pair of spectra in the library. The spectrometer further includes a processor coupled to the memory device and configured to determine a spectrum of the mixture based on the signal generated by the detector, calculate a correlation vector that includes a correlation between the mixture spectrum and each spectrum in the library, and identify the mixture based on the correlation matrix and the correlation vector.

Abstract translation: 提供了用于识别混合物的光谱仪。 该分光计包括配置成基于光与混合物的样本的相互作用产生信号的检测器以及具有存储在其中的库和相关矩阵的存储器设备，其中该库包括多个谱，每个谱与 相应的化合物，并且其中相关矩阵包括库中每个可能的谱对对之间的相关性。 所述光谱仪还包括处理器，所述处理器耦合到所述存储器装置，并且被配置为基于由所述检测器生成的信号来确定所述混合物的光谱，计算包括所述混合物光谱和所述库中的每个光谱之间的相关性的相关性矢量， 基于相关矩阵和相关向量的混合。

公开(公告)号：EP0846253A4

公开(公告)日：2009-11-11

申请号：EP96926226

申请日：1996-08-02

Applicant: ROCHE DIAGNOSTICS OPERATIONS

Inventor： PRICE JOHN F ,  LONG JAMES R

IPC: G01N33/483 ,  G01J3/28 ,  G01N21/27 ,  G01N21/35 ,  G01N33/50 ,  G01N33/66 ,  G01N33/68 ,  G01N33/92 ,  G01N37/00 ,  G01J3/457

CPC classification number: G01N21/274 ,  G01J2003/2866 ,  G01N21/359

公开(公告)号：EP1790971A1

公开(公告)日：2007-05-30

申请号：EP06254372.3

申请日：2006-08-21

Applicant: Servomex Group Ltd

Inventor： Hobby, James ,  Lopez, Martin

IPC: G01N21/35 ,  G01N21/61 ,  G01N21/27 ,  G01J3/457

CPC classification number: G01N21/3504 ,  G01J3/457 ,  G01N21/274 ,  G01N21/37 ,  G01N21/61

Abstract: Correlation spectroscopy measure is improved by correcting for cross interference. This is achieved through applying different gains to the output signals whereby the effect of background interferent species can be calculated and an automatic correction factor applied.

Abstract translation: 通过校正交叉干扰来改进相关光谱测量。 这通过对输出信号应用不同的增益来实现，从而可以计算背景干扰物质的效果并应用自动校正因子。

公开(公告)号：EP1616158A1

公开(公告)日：2006-01-18

申请号：EP04727848.6

申请日：2004-04-16

Applicant: DLR Deutsches Zentrum für Luft- und Raumfahrt e.V.

Inventor： KLINGENBERG, Hans, H. ,  FIX, Andreas ,  MAHNKE, Peter ,  LEMMERZ, Christian

IPC: G01J3/457

CPC classification number: G01N21/3504 ,  G01J3/457 ,  G01N21/39 ,  G01N2021/1793 ,  G01N2021/3513 ,  G01N2021/392 ,  G01N2021/395 ,  G01N2021/399

Abstract: The invention relates to a mobile remote detection device for accumulations of methane, comprising an emitter device having a light source in order to generate air, the wave length of said light source being synchronised with the spectral signature of methane, whereby the light can be directed towards a measuring field. Said detection device also comprises a detector device for detecting backscattered light, and an evaluation device. The aim of the invention is to improve said remote detection device in such a manner that it has a high degree of measuring sensitivity with a compact and stabile structure. According to the invention, the light source generates light at a wave length of between 3200nm and 3300nm at which methane is absorbed and the light source has an optical parametric oscillator with seed-injection, said oscillator being associated with a pump laser which is operated in seed-injection mode.

公开(公告)号：EP1367383A1

公开(公告)日：2003-12-03

申请号：EP02012155.4

申请日：2002-06-01

Applicant: Siemens Building Technologies AG

Inventor： Forster, Martin, Dr. ,  Pleisch, Rolf

IPC: G01N21/35 ,  G01J3/457

CPC classification number: G01J3/457 ,  G01N21/3504

Abstract: Ein optischer Gasmelder für den Nachweis von Substanzen, welche bei einer Wellenlänge von 11 ± 2 µm absorbieren, enthält eine Lichtquelle (10), eine Messzelle (6) mit einem Messfilter (11), eine Referenzzelle (7) mit einem Referenzfilter (12), und eine Auswerteelektronik. Das Referenzfilter (12) hat einen Durchlassbereich, welcher an ein mögliches Störgas angepasst ist. Vorzugsweise weist das Messfilter (11) einen Durchlassbereich von 11 ± 2 µm und das Referenzfilter (12) einen vom Messfilter (11) verschiedenen Durchlassbereich auf, wobei der letztere im Wellenlängenbereich von 7.2 µm bis 8.7 µm und/oder von 3.02 µm bis 4.0 µm liegt.

Abstract translation: 光学气体传感器包括光源（10），具有测量滤光片（11）的测量单元（6），具有参考滤光片（12）的参考单元（7），所述参考滤光片（12）具有用于可能的外界气体的通道区域 电子单位。

公开(公告)号：EP0822395A3

公开(公告)日：2000-06-07

申请号：EP97113097.6

申请日：1997-07-30

Applicant: BASF AKTIENGESELLSCHAFT

Inventor： Schrof, Wolfgang, Dr. ,  Klingler, Jürgen, Dr. ,  Horn, Dieter, Dr.

IPC: G01J3/44 ,  G01J3/457 ,  G01N15/02

CPC classification number: G01J3/457 ,  G01J3/44 ,  G01J2003/2866

Abstract: In dem Verfahren und der Vorrichtung zur Bestimmung von Diffusionsparametern, Konzentration, Größe oder Strömungsverhalten von Partikeln in einer Probe, werden Anregungslicht einer Lichtquelle in die Probe geleitet, Raman-Streulicht aus einem Beobachtungsvolumen der Probe aufgefangen und einem Spektrographen zugeführt wird, wo es in Spektrallinien zerlegt wird, wobei die Intensität mindestens einer Spektrallinie mindestens 10 mal pro Sekunde mit jeweils einem Photodetektor gemessen wird, und aus den gemessenen Intensitätswerten für die jeweilige Spektrallinie durch eine Fluktuationsanalyse, vorzugsweise eine Autokorrelation oder eine Frequenzanalyse, Diffusionsparameter, Konzentration, Größe oder Strömungsverhalten der Partikel, denen die jeweilige Spektrallinie zuzuordnen ist, berechnet. Bei diesem Verfahren können auch Signale verschiedener Spektrallinien oder -banden oder Signale von Raman-Streulicht, quasielastisch gestreutem Licht und Fluoreszenzlicht miteinander korreliert werden.

公开(公告)号：EP0801737A4

公开(公告)日：1999-03-31

申请号：EP95943410

申请日：1995-12-13

Applicant: EXXON RESEARCH ENGINEERING CO

Inventor： PERRY BRUCE N ,  BROWN JAMES M

IPC: G01N21/27 ,  G01N21/35 ,  G01J3/457

CPC classification number: G01N21/3577

Abstract: Research octane number (RON), or other physical or chemical properties or composition data, of a test sample is obtained by infrared spectral analysis of the test sample and a calibration sample set. The determination of the above properties is improved by using the spectrum of the test sample, a linear prediction model, and a nonlinear correction to the linear prediction model.

公开(公告)号：EP4332551A1

公开(公告)日：2024-03-06

申请号：EP22796166.1

申请日：2022-04-28

Applicant: The Asan Foundation ,  University Of Ulsan Foundation For Industry Cooperation

Inventor： KIM, Sang Yeob ,  PACK, Chan Gi

IPC: G01N21/64 ,  G01N33/58 ,  G01J3/44 ,  G01J3/457

Abstract: The present disclosure relates to a method of quantitatively analyzing fluorescence dyes labeled on extracellular vesicles by using fluorescence correlation spectroscopy and use thereof, in which the number of the labeled fluorescence dyes per extracellular vesicle can be quantified, and thus the labeling efficiency of the fluorescence dyes can be accurately measured. In addition, extracellular vesicles included in an unidentified sample can be quantified using fluorescence dyes of which the labeling efficiency has been measured, and more accurate biodistribution experimental results can be obtained. Thus, the extracellular vesicles can be used to evaluate a therapeutic candidate material and can also be used in the quantification of a target protein in vivo, and thus can be widely used.

公开(公告)号：EP3951337A1

公开(公告)日：2022-02-09

申请号：EP20785108.0

申请日：2020-03-27

Applicant: Hamamatsu Photonics K.K.

Inventor： INOUE, Takashi

IPC: G01J3/457 ,  G01J11/00 ,  G01M11/00 ,  H01S3/00 ,  H01S3/10

Abstract: A dispersion measurement apparatus 1A includes a pulse forming unit 3, a correlation optical system 4, a photodetection unit 5, and an operation unit 6. The pulse forming unit 3 forms a light pulse train Pb including a plurality of light pulses having time differences and center wavelengths different from each other from a measurement target light pulse Pa output from a pulsed laser light source 2. The correlation optical system 4 receives the light pulse train Pb output from the pulse forming unit 3 and outputs correlation light Pc including a cross-correlation or an autocorrelation of the light pulse train Pb. The photodetection unit 5 detects a temporal waveform of the correlation light Pc output from the correlation optical system 4. The operation unit 6 estimates a wavelength dispersion amount of the pulsed laser light source 2 based on a feature value of the temporal waveform of the correlation light Pc. Thus, a dispersion measurement apparatus, a pulsed light source, a dispersion measurement method, and a dispersion compensation method capable of measuring a wavelength dispersion by a simple configuration are realized.

公开(公告)号：EP2702376A1

公开(公告)日：2014-03-05

申请号：EP12718601.3

申请日：2012-04-27

Applicant: Menlo Systems GmbH ,  Ecole Polytechnique Fédérale de Lausanne (EPFL)

Inventor： KIPPENBERG, Tobias ,  HOLZWARTH, Ronald

IPC: G01J3/42 ,  G01J3/453 ,  G02B6/12 ,  G01J3/457

CPC classification number: G01J3/45 ,  G01J3/42 ,  G01J3/4531 ,  G01J3/4532 ,  G01J3/457 ,  G02B6/12007 ,  G02B6/29338 ,  G02B6/29353

Abstract: The invention relates to a spectroscopy array having a first and a second optical ring resonator (1, 3), each provided with a material having an intensity-dependent refraction index. The spectroscopy array further comprises at least one waveguide (2, 4, 7, 8), which is guided along the optical ring resonator at a distance such that the light of a continuous beam laser (2b, 4b, 20) guided in the waveguide (2, 4, 7) can be coupled into the optical ring resonator (1, 3), and a frequency comb generated from the light of the continuous beam laser in the optical ring resonator can be coupled out of the waveguide (2, 4, 8). The optical ring resonators (1, 3) and the at least one waveguide (2, 4, 7, 8) are provided on a shared substrate (9).