公开(公告)号：EP3539035B1

公开(公告)日：2024-04-17

申请号：EP17805344.3

申请日：2017-11-07

IPC分类号： G16B25/00 ,  G06F16/22 ,  G06F16/28 ,  G16B40/00 ,  G16B99/00 ,  G16B25/10 ,  G16B40/30

CPC分类号： G16B99/00 ,  G16B25/00 ,  G06F16/283 ,  G06F16/2246 ,  G16B40/00 ,  G16B40/30 ,  G16B25/10

公开(公告)号：EP4332977A2

公开(公告)日：2024-03-06

申请号：EP23209565.3

申请日：2019-05-01

申请人： Castle Biosciences, Inc.

发明人： COOK, Robert Willis ,  COVINGTON, Kyle R. ,  MAETZOLD, Derek

IPC分类号： G16B99/00

摘要： The present disclosure relates to methods for predicting the risk of recurrence and/or metastasis in primary cutaneous squamous cell carcinoma (cSCC).

公开(公告)号：EP4100956A1

公开(公告)日：2022-12-14

申请号：EP21751263.1

申请日：2021-01-30

申请人： Her Majesty The Queen in Right of Canada, as Represented by The Minister of Agriculture and Agri-Food ,  Wieden, Hans-Joachim ,  Smith, Dustin D. ,  Girodat, Dylan ,  Roberts, Luc Arden Hamilton

发明人： ABBOTT, D. Wade ,  WIEDEN, Hans-Joachim ,  SMITH, Dustin D. ,  GIRODAT, Dylan ,  ROBERTS, Luc Arden Hamilton

IPC分类号： G16B99/00 ,  C07K14/24 ,  C07K14/245 ,  C07K14/315 ,  G01N33/53 ,  G01N33/66 ,  G16B15/00 ,  G16B15/30 ,  G16C99/00

公开(公告)号：EP3909053A1

公开(公告)日：2021-11-17

申请号：EP20738077.5

申请日：2020-01-06

申请人： Personal Genome Diagnostics Inc.

发明人： ANGIUOLI, Samuel, V. ,  RILEY, David

IPC分类号： G16B30/00 ,  G16B99/00 ,  G06F11/30

公开(公告)号：EP3798321A1

公开(公告)日：2021-03-31

申请号：EP20196060.6

申请日：2016-12-15

申请人： Illumina, Inc.

发明人： TOUNG, Jonathan ,  LIU, Li ,  SHEN, Min-Jui, Richard ,  ZHANG, Ruoyo

IPC分类号： C12Q1/6881 ,  C12Q1/6886 ,  G16B40/00 ,  G16B99/00

摘要： Provided herein is a method for distinguishing an aberrant methylation level for DNA from a first cell type, including steps of (a) providing a test data set that includes (i) methylation states for a plurality of sites from test genomic DNA from at least one test organism, and (ii) coverage at each of the sites for detection of the methylation states; (b) providing methylation states for the plurality of sites in reference genomic DNA from one or more reference individual organisms, (c) determining, for each of the sites, the methylation difference between the test genomic DNA and the reference genomic DNA, thereby providing a normalized methylation difference for each site; and (d) weighting the normalized methylation difference for each site by the coverage at each of the sites, thereby determining an aggregate coverage-weighted normalized methylation difference score. Also provided herein are sensitive methods for using genomic DNA methylation levels to distinguish cancer cells from normal cells and to classify different cancer types according to their tissues of origin.

公开(公告)号：EP3422014B1

公开(公告)日：2024-07-24

申请号：EP17382400.4

申请日：2017-06-27

IPC分类号： G01N35/00 ,  G16B50/00 ,  G16B99/00 ,  G16H10/40

CPC分类号： G01N35/00871 ,  G16H10/40 ,  G16B99/00 ,  G16B50/00

公开(公告)号：EP4271829A2

公开(公告)日：2023-11-08

申请号：EP21848052.3

申请日：2021-11-29

申请人： Technische Universiteit Delft

发明人： PABST, Martin ,  LOOSDRECHT, VAN, Marinus Cornelius Maria ,  KLEIKAMP, Hugobert Bernhard Crijn

IPC分类号： C12Q1/04 ,  C12Q1/06 ,  C12Q1/689 ,  C12Q1/68 ,  G16B99/00

公开(公告)号：EP3438651B1

公开(公告)日：2023-09-13

申请号：EP18190951.6

申请日：2011-10-05

发明人： HUBER, Fritz ,  KIRCHHÖFER, Renate ,  PFAHLERT, Volker

IPC分类号： G01N24/08 ,  G01R33/46 ,  A61B5/055 ,  G16B40/10 ,  G16B40/20 ,  G16B99/00 ,  G16B40/00

公开(公告)号：EP3408413B1

公开(公告)日：2022-09-07

申请号：EP17745004.6

申请日：2017-01-27

发明人： LILLEY, Patrick ,  NUNEZ, Matthew

IPC分类号： C12Q1/6883 ,  A61P19/02 ,  G16B99/00

公开(公告)号：EP4016433A1

公开(公告)日：2022-06-22

申请号：EP19941912.8

申请日：2019-08-26

申请人： Clinomics Inc.

发明人： KIM, Byung Chul ,  BHAK, Jong Hwa ,  CHO, Yun Sung ,  CHO, Su An

IPC分类号： G06Q30/06 ,  G16B99/00 ,  A61B5/021 ,  A61B5/00

摘要： The present invention may provide a system for recommending a user-customized beverage through a genetic test, and a method for driving same, the system comprising: a genetic information acquisition unit for acquiring user's genetic information from a result of a user's genetic test; and a beverage recommendation unit for recommending at least one user-customized recommendable beverage on the basis of the genetic information acquired from the genetic information acquisition unit, wherein the system for recommending a user-customized beverage through a genetic test can recommend a customized-beverage to a user by reflecting a genotype through the user's genetic test.