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公开(公告)号:EP4388080A1
公开(公告)日:2024-06-26
申请号:EP22859436.2
申请日:2022-08-19
IPC分类号: C12N1/36 , A61K39/015 , A61P33/06
CPC分类号: Y02A50/30 , C12N1/36 , A61K39/015 , A61P33/06 , C07K14/445 , A61K2039/52220130101
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公开(公告)号:EP4265271A3
公开(公告)日:2024-02-21
申请号:EP23184802.9
申请日:2020-05-11
发明人: Hill, Adrian Vivian Sinton , Bettencourt, Paulo Jorge Goncalves de , Spencer, Alexandra Jane , Ternette, Nicola Maria Nathalie , Salman, Ahmed Mahmoud Ahmed Ahmed , Junqueira, Caroline Furtado , Gazzinelli, Ricardo Tostes , Barbosa, Camila Raquel Rodrigues
IPC分类号: A61K39/015
摘要: An immunogenic composition comprising: a) one or more plasmodium-derived ribosomal or ribosomal associated protein or immunogenic fragment thereof which has a sequence which is at least about 80%, 85%, 90%, 95%, 98%, 99% or 100% identical to a ribosomal or ribosomal associated protein or an immunogenic fragment of a ribosomal or ribosomal associated protein recited in Figure 1; or a ribosomal or ribosomal associated protein or peptide or immunogenic fragment thereof as recited in Figure 2 or Figure 3; and/or b) a polynucleotide encoding one or more protein, peptide or immunogenic fragment of a); wherein the immunogenic composition is for use in eliciting an immune response in a subject to treat or prevent malaria. Also provided are plasmodium-derived ETRAMPs and/or histones, or immunogenic fragments thereof, for use in eliciting an immune response in a subject, preferably to treat or prevent malaria.
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公开(公告)号:EP3125929B8
公开(公告)日:2023-12-27
申请号:EP15713532.8
申请日:2015-04-02
IPC分类号: A61K39/002 , A61K39/015 , A61K39/29 , A61K39/39
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公开(公告)号:EP4147715A1
公开(公告)日:2023-03-15
申请号:EP22182920.3
申请日:2017-07-21
申请人: VAC4all Pte. Ltd.
发明人: Druilhe, Pierre
IPC分类号: A61K39/015 , A61K39/385 , A61K39/00
摘要: The invention relates to fusion proteins which comprise at least one antigenic amino acid sequence fused to a carrier heterologous protein sequence, wherein the antigenic sequence comprises an epitopic sequence of a Plasmodium protein and the carrier heterologous protein sequence is a sequence that is immunogenic in humans. The proteins are useful as anti-malaria vaccines.
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公开(公告)号:EP3004348B1
公开(公告)日:2023-03-08
申请号:EP14807026.1
申请日:2014-06-02
发明人: UENO, Ryuji , AKAHATA, Wataru
IPC分类号: A61K39/015 , A61K39/12 , C12N15/09 , C07K14/18 , C07K14/445 , C07K19/00 , C12N7/00
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公开(公告)号:EP3976061A1
公开(公告)日:2022-04-06
申请号:EP20818190.9
申请日:2020-06-03
IPC分类号: A61K31/787 , A61K39/015 , A61K39/145 , A61K39/39 , A61K47/54 , A61K47/58
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公开(公告)号:EP3962523A2
公开(公告)日:2022-03-09
申请号:EP20727798.9
申请日:2020-05-04
IPC分类号: A61K39/015 , A61P33/06 , C07K16/20 , A61K39/00
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公开(公告)号:EP3962513A1
公开(公告)日:2022-03-09
申请号:EP20722332.2
申请日:2020-04-30
IPC分类号: A61K38/03 , A61K39/015 , A61P33/06 , C07K16/20 , A61K39/00
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公开(公告)号:EP3661968B1
公开(公告)日:2022-03-02
申请号:EP18841800.8
申请日:2018-08-03
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公开(公告)号:EP3946441A1
公开(公告)日:2022-02-09
申请号:EP20713331.5
申请日:2020-03-30
IPC分类号: A61K39/015 , A61P33/06 , C07K14/00
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