公开(公告)号：EP4388080A1

公开(公告)日：2024-06-26

申请号：EP22859436.2

申请日：2022-08-19

申请人： Seattle Children's Hospital d/b/a Seattle Children's Research Institute

发明人： GOSWAMI, Debashree ,  KAPPE, Stefan, H.I. ,  VAUGHAN, Ashley, Michael

IPC分类号： C12N1/36 ,  A61K39/015 ,  A61P33/06

CPC分类号： Y02A50/30 ,  C12N1/36 ,  A61K39/015 ,  A61P33/06 ,  C07K14/445 ,  A61K2039/52220130101

公开(公告)号：EP2910630B1

公开(公告)日：2018-10-24

申请号：EP15153935.0

申请日：2010-09-23

申请人： REG Life Sciences, LLC

发明人： Gaertner, Alfred

IPC分类号： C12N9/10 ,  C12N1/21 ,  C12P7/64

CPC分类号： C12N9/1029 ,  C10L1/026 ,  C10L1/19 ,  C11C3/10 ,  C12N1/36 ,  C12N9/001 ,  C12N15/63 ,  C12P7/649 ,  C12Y103/99003 ,  C12Y203/01075 ,  Y02E50/13

摘要： Methods and compositions for producing fatty acid derivatives, for example, fatty esters, and commercial fuel compositions comprising fatty acid derivatives are described.

公开(公告)号：EP2912100B1

公开(公告)日：2018-09-05

申请号：EP13780362.3

申请日：2013-10-24

申请人： Fritz Egger GmbH & Co. OG

发明人： KUNCINGER, Thomas ,  GRADINGER, Cornelia ,  STRATEV, Daniel

IPC分类号： C08H8/00 ,  B27K5/00 ,  B27N1/00 ,  B27N3/02 ,  B27N3/04 ,  C12N1/04 ,  C12N1/36 ,  C21C5/00 ,  C12R1/00

CPC分类号： C12N1/20 ,  C08H8/00 ,  C12N1/36

公开(公告)号：EP3310380A1

公开(公告)日：2018-04-25

申请号：EP16730689.3

申请日：2016-06-16

申请人： Vaximm AG

发明人： LUBENAU, Heinz

IPC分类号： A61K39/02

CPC分类号： A61K39/0011 ,  A61K39/245 ,  A61K45/06 ,  A61K2039/522 ,  A61K2039/523 ,  A61K2039/542 ,  A61K2039/585 ,  A61P31/22 ,  A61P35/00 ,  C07K14/005 ,  C12N1/36 ,  C12N2710/16122 ,  C12N2710/16134 ,  Y02A50/484

摘要： The present invention relates to an attenuated strain of Salmonella comprising a DNA molecule encoding CMV pp65. In particular, the present invention relates to the use of said attenuated strain of Salmonella in cancer immunotherapy.

公开(公告)号：EP3289068A1

公开(公告)日：2018-03-07

申请号：EP16722317.1

申请日：2016-04-27

申请人： Lesaffre et Compagnie

发明人： BAVOUZET, Jean-Michel ,  DESFOUGERES, Thomas ,  PIGNEDE, Georges ,  TECHEL, Jennifer

IPC分类号： C12N1/18 ,  C12N1/19 ,  C12N1/36 ,  C12P7/10 ,  C12R1/865

CPC分类号： C12N1/18 ,  C12N1/16 ,  C12N1/36 ,  C12P7/06 ,  C12P7/10 ,  C12R1/865 ,  Y02E50/16 ,  Y02E50/17

摘要： The invention relates to a method for selecting a yeast strain having improved capability for fermenting a pentose, advantageously xylose, in the presence of organic acid, advantageously acetic acid, in non-dissociated form, in which at least one yeast strain that is capable of fermenting said pentose is consecutively cultured in the following two media: a first growth medium comprising said pentose as the only carbon source and said organic acid in non-dissociated form; a second growth medium comprising another carbon source as the only carbon source, advantageously glucose, free of said organic acid in non-dissociated form, the consecutive culture in at least said two growth media being repeated at least twice, in the presence of rising concentrations of organic acid in non-dissociated form.

公开(公告)号：EP3273989A1

公开(公告)日：2018-01-31

申请号：EP16767548.7

申请日：2016-03-24

申请人： GPN VACCINES PTY LTD

发明人： BABB, Rachelle ,  ALSHARIFI, Mohammed ,  CHEN, Austen Yannis ,  DAVID, Shannon Christa ,  HIRST, Timothy Raymond ,  OGUNNIYI, Abiodun David ,  PATON, James Cleland

IPC分类号： A61K39/09 ,  A61P11/00 ,  A61P31/04

CPC分类号： A61K39/092 ,  A61K2039/521 ,  A61K2039/523 ,  A61K2039/54 ,  A61K2039/541 ,  A61K2039/543 ,  A61K2039/55544 ,  A61K2039/58 ,  A61P31/04 ,  C12N1/36 ,  C12N13/00 ,  C12N15/01

摘要： The present invention relates to photon-irradiated streptococcal vaccine preparations and methods for their use.

公开(公告)号：EP2699668B1

公开(公告)日：2017-11-29

申请号：EP12717561.0

申请日：2012-04-20

申请人： Danisco US Inc.

发明人： BODIE, Elizabeth A. ,  PRATT II, Robert James

IPC分类号： C12N1/14 ,  C12N15/01 ,  C12N1/36 ,  C12N9/24 ,  C12N15/79 ,  C12N15/80

CPC分类号： C12N15/79 ,  C12N1/14 ,  C12N1/36 ,  C12N9/2405 ,  C12N15/80

摘要： Described are compositions and methods relating to variant filamentous fungi having altered growth characteristics. Such variants are well-suited for growth in submerged cultures, e.g., for the large-scale production of enzymes and other proteins for commercial applications.

公开(公告)号：EP2912198B1

公开(公告)日：2017-11-22

申请号：EP13792604.4

申请日：2013-10-24

申请人： Pharmaq AS

发明人： TUNG, Vo Thanh ,  PHUONG, Tran Duy ,  PHUONG, Le Thi Kim ,  PHUC, Nguyen Truong ,  NYGAARD, Anja ,  HUNGERHOLDT, Liv Blom ,  KLEVAN, Leif Are

IPC分类号： C12R1/01 ,  A61K39/02 ,  C12N1/20 ,  C12N1/36

CPC分类号： A61K39/025 ,  A61K2039/521 ,  A61K2039/552 ,  C12N1/20 ,  C12N1/36 ,  C12R1/01

公开(公告)号：EP2882845B1

公开(公告)日：2017-10-25

申请号：EP12761807.2

申请日：2012-08-07

申请人： Institut Pasteur

发明人： CARNIEL, Elisabeth ,  DEMEURE, Christian ,  DERBISE, Anne

IPC分类号： C12N1/36 ,  A61K39/102

CPC分类号： A61K39/0291 ,  A61K2039/522 ,  A61K2039/523 ,  A61K2039/542 ,  C12N1/36 ,  Y02A50/407

摘要： The application relates to a Yersinia pseudotuberculosis cell, which comprises nucleic acid coding for expression of at least one Yersinia pestis Caf1 polypeptide or of at least one antigenic fragment of Yersinia pestis Caf1, more particularly to an attenuated Y. pseudotuberculosis cell, which expresses the Y. pestis capsule. Said Y. pseudotuberculosis cell is exceptionally efficient in protecting against both bubonic plague and pulmonary plague.

公开(公告)号：EP2403525B1

公开(公告)日：2017-09-27

申请号：EP10749113.6

申请日：2010-02-24

申请人： University of Maryland, Baltimore

发明人： VINDURAMPULLE, Christofer ,  BARRY, Eileen, M. ,  LEVINE, Myron, M. ,  GALEN, James

IPC分类号： A61K39/112 ,  C12N1/21 ,  C12N15/31 ,  C12R1/42

CPC分类号： A61K39/0275 ,  A61K2039/522 ,  A61K2039/6068 ,  C12N1/36 ,  Y02A50/482

摘要： The present invention is drawn to a live, attenuated S. Paratyphi A strain, a live, attenuated S. Paratyphi A strain comprising a stabilized plasmid expression system, an S. Paratyphi conjugate vaccine, and methods of using these strains and conjugate vaccine.

摘要翻译： 本发明涉及减毒的活的减毒链球菌A株，减毒的减毒链球菌A株，稳定的质粒表达系统，伤寒沙门氏菌缀合物疫苗，以及使用这些菌株和缀合物疫苗的方法。