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公开(公告)号：EP4406535A3
公开(公告)日：2024-11-06
申请号：EP24168728.4
申请日：2014-10-31
申请人： Allergan, Inc.
IPC分类号： A61K9/16 , A61K47/10 , A61K47/34 , A61K31/5575 , A61P27/02 , A61P27/06 , A61K31/165
摘要： Prostamide-containing intraocular implants that biodegrade in the eye and that are effective for reducing intraocular pressure in an eye for a sustained period. The implants generally contain a prostamide, such as bimatoprost, and at least three distinct biodegradable polymers selected from polylactide and poly(lactide-co-glycolide) polymers and are optimized for placement in and compatibility with the anterior chamber of the eye, particularly the anterior chamber angle. Methods for making and using the implants to reduce ocular hypertension and intraocular pressure in a patient are described.
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公开(公告)号：EP4452233A1
公开(公告)日：2024-10-30
申请号：EP22843886.7
申请日：2022-12-20
发明人： NUR, Israel , GRIMBERG, Elena , PODOLER, Itai , TZELIK, Shirly
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公开(公告)号：EP3981391B1
公开(公告)日：2024-10-30
申请号：EP20817973.9
申请日：2020-05-27
发明人： LIM, Nak Hyun , KIM, Jeom Yong , YOO, Young Hyo , PARK, Sun Kyu
IPC分类号： A61K36/258 , A61K9/16 , A61K9/48 , A61K9/20
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公开(公告)号：EP4444279A1
公开(公告)日：2024-10-16
申请号：EP22846530.8
申请日：2022-07-19
申请人： Boston, Judith
发明人： Boston, Judith
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公开(公告)号：EP4436551A1
公开(公告)日：2024-10-02
申请号：EP22814493.7
申请日：2022-11-25
申请人： Orexo AB
发明人： SÄVMARKER, Jonas , RÖNN, Robert
CPC分类号： A61K9/1652 , A61K9/1623 , A61K9/1694 , A61M15/08 , A61K38/47 , A61M11/02 , A61M15/0043 , A61M2205/07320130101 , A61M15/0061 , C12Y302/01023 , A61K38/162
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公开(公告)号：EP4400098A3
公开(公告)日：2024-10-02
申请号：EP24178410.7
申请日：2020-12-04
申请人： Zerion Pharma Aps
发明人： LÖBMANN, Korbinian , LENG, Donglei , WIBORG, Ole
CPC分类号： A61K9/146 , A61K9/1658
摘要： The present invention relates to co-amorphous forms of a drug substance and a protein, more particularly beta-lactoglobulin, wherein the purity of the beta-lactoglobulin is at least 94% (w/w) of the total amount of protein comprised in the co-amorphous form. The present invention also relates to compositions, such as pharmaceutical compositions, comprising the co-amorphous form.
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公开(公告)号：EP4393478A3
公开(公告)日：2024-09-11
申请号：EP24161253.0
申请日：2022-07-08
发明人： JOSHI, Vidya , ARCHBELL, James , LACHACZ, Kellisa , LAMPA, Charina , MELLO, Lauren , GUTIERREZ, Gertrude , LECHUGA-BALLESTEROS, David , TAN, Penny , RIEBE, Michael
IPC分类号： A61K31/167 , A61K31/40 , A61K31/58 , A61P1/00 , A61K9/16
CPC分类号： A61K9/008 , A61P1/00 , A61K45/06 , A61K31/58 , A61K31/167 , A61K31/40 , A61K9/1617
摘要： Compositions, methods, and systems are provided for pulmonary delivery of active agents via a metered dose inhaler. In some embodiments, the compositions comprise an HFO-1234ze(E) suspension medium, active agent particles, and suspending particles. The active agent particles may comprise one, two, three or four active agent(s) selected from a long-acting muscarinic antagonist (LAMA), a long-acting β2-agonists (LABA), a short-acting beta-agonists (SABA), an inhaled corticosteroid (ICS), and a non-corticosteroid anti-inflammatory agent.
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公开(公告)号：EP4103158B1
公开(公告)日：2024-09-04
申请号：EP21705458.4
申请日：2021-02-10
IPC分类号： A61K9/20 , A61K9/16 , A61K31/403 , A61K31/404
CPC分类号： A61K9/2027 , A61K9/2054 , A61K9/1635 , A61K31/403 , A61K31/404
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公开(公告)号：EP4419086A1
公开(公告)日：2024-08-28
申请号：EP22800367.9
申请日：2022-10-19
申请人： Novartis AG
发明人： BHASIN, Saket , KULKARNI, Swati
IPC分类号： A61K9/16 , A61K9/48 , A61K31/4747
CPC分类号： A61K9/4866 , A61K9/1635 , A61K9/1694 , A61K31/4747
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公开(公告)号：EP4196097B1
公开(公告)日：2024-08-28
申请号：EP21794765.4
申请日：2021-10-13
CPC分类号： A61K47/6935 , A61K9/1623 , A61K9/1694 , A61K9/5123 , A61K47/644 , A61K47/59
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