PROCESSES FOR PREPARING A (1,2-DIMETHYL-3-METHYLENECYCLOPENTYL)ACETATE COMPOUND AND (1,2-DIMETHYL-3-METHYLENECYCLOPENTYL)ACETALDEHYDE

    公开(公告)号:EP4101833A1

    公开(公告)日:2022-12-14

    申请号:EP22177606.5

    申请日:2022-06-07

    摘要: The present invention provides a process for preparing a (1,2-dimethyl-3-methylenecyclopentyl)acetate compound of the following general formula (3), wherein R represents a linear or branched alkyl group having 1 to 4 carbon atoms, the process comprising subjecting a haloacetaldehyde alkyl 2,3-dimethyl-2-cyclopentenyl acetal compound of the following general formula (1), wherein R is as defined above, and Y represents a halogen atom, to a dehydrohalogenation reaction in the presence of a base, followed by a rearrangement reaction to obtain a (1,2-dimethyl-2-cyclopentenyl)acetate compound of the following general formula (2), wherein R is as defined above, and subjecting the (1,2-dimethyl-2-cyclopentenyl)acetate compound (2) to an epoxidation reaction, followed by an isomerization reaction and then a methylenation reaction to obtain the (1,2-dimethyl-3-methylenecyclopentyl)acetate compound of the following general formula (3). The present invention also provides a process for preparing (1,2-dimethyl-3-methylenecyclopentyl)acetaldehyde of the following formula (4), the process comprising the aforesaid process for preparing the (1,2-dimethyl-3-methylenecyclopentyl)acetate compound (3), and converting an alkoxycarbonylmethyl group (i.e., -CH 2 C(=O)OR) of the (1,2-dimethyl-3-methylenecyclopentyl)acetate compound (3) to a formylmethyl group (i.e., -CH 2 CHO) to obtain (1,2-dimethyl-3-methylenecyclopentyl)acetaldehyde (4).

    PROCESSES FOR PREPARING ALPHA-NECRODYL COMPOUNDS AND PROCESSES FOR PREPARING GAMMA-NECRODYL COMPOUNDS

    公开(公告)号:EP3943474A1

    公开(公告)日:2022-01-26

    申请号:EP21186479.8

    申请日:2021-07-19

    摘要: The present invention provides processes for preparing an α-necrodyl compound of the following general formula (3): wherein R 2 represents a monovalent hydrocarbon group having 1 to 9 carbon atoms, the process comprising: subjecting a 3, 5, 5-trimethyl-3-cyclopentene compound of the following general formula (1): wherein R 2 is as defined above, and X represents a leaving group, to a nucleophilic substitution reaction with a methylating agent of the following general formula (2): wherein M represents Li, MgZ 1 , ZnZ 1 , Cu, CuZ 1 , or CuLiZ 1 , and Z 1 represents a halogen atom or a methyl group, to form the α-necrodyl compound (3). The present invention further provides processes for preparing γ-necrodyl compounds of the following general formula (4): wherein R 2 represents a monovalent hydrocarbon group having 1 to 9 carbon atoms, the process comprising: subjecting the α-necrodyl compound (3) thus obtained to a positional isomerization reaction at the double bond to form the γ-necrodyl compound (4).

    CARBON-BASED, PRECIOUS METAL-TRANSITION METAL COMPOSITE CATALYST AND PREPARATION METHOD THEREFOR

    公开(公告)号:EP3907000A1

    公开(公告)日:2021-11-10

    申请号:EP19906643.2

    申请日:2019-12-10

    摘要: The present invention relates to a carbon-based precious metal-transition metal composite catalyst and a preparation method therefor, and more particularly, to a catalyst synthesis method in which, when preparing a high-content precious metal-transition metal composite catalyst, a catalyst having uniform particles and composition can be prepared, and cyclohexane dimethanol (CHDM) is efficiently produced by the hydrogenation reaction of cyclohexane dicarboxylic acid (CHDA) in an aqueous solution. Provided is a method for preparing a carbon-based precious metal-transition metal composite catalyst, wherein, in the carbon-based precious metal-transition metal composite catalyst, the precious metal is included in an amount of 10-20 parts by weight, and the transition metal is included in an amount of 10-20 parts by weight based on 100 parts by weight of the composite catalyst, and thus a total amount of the precious metal-transition metal is 20-40 parts by weight based on 100 parts by weight of the composite catalyst.