公开(公告)号：JP2011088848A

公开(公告)日：2011-05-06

申请号：JP2009242930

申请日：2009-10-22

申请人： Anri Japan:Kk ,  Bihadaclub Ltd ,  株式会社安理ジャパン ,  美肌倶楽部有限会社

发明人： ITABASHI TAKAKO ,  FUTAMURA YOSHIHIRO

IPC分类号： A61K38/00 ,  A61P29/00 ,  A61P37/08

摘要： PROBLEM TO BE SOLVED: To provide a method for producing an anthocyanidin peptide derivative which is weak in side effects and has an antiinflammatory effect.
SOLUTION: The anthocyanidin peptide derivative having an antiinflammatory effect refers to a compound in which two molecules of anthocyanidin are combined with phenylalanyl-alanyl-phenylalanyl-valine. Phenylalanine is in the N-terminal position, and valine is in the C-terminal position. The method for producing the anthocyanidin peptide derivative includes the steps of: adding dextrose and lactic acid bacterium to a ground product of black soybean, fermenting the mixture, protecting fermented mash with α-cyclodextrin, digesting the protected mash with protease followed by filtration, treating the resulting filtration residue with cellulase, and extracting the treated residue with ethanol. The anthocyanidin peptide derivative having an antiinflammatory effect is utilized for medicine, cosmetics, daily necessities, and the like.
COPYRIGHT: (C)2011,JPO&INPIT

摘要翻译： 待解决的问题：提供一种副作用弱的具有抗炎作用的花色素肽衍生物的制造方法。 解决方案：具有抗炎作用的花色素肽衍生物是指将两分子花色素与苯丙氨酰 - 丙氨酰 - 苯丙氨酰 - 缬氨酸组合的化合物。 苯丙氨酸处于N-末端位置，缬氨酸处于C末端位置。 花色素肽衍生物的制造方法包括以下步骤：向黑豆的研磨产物中加入葡萄糖和乳酸菌，发酵混合物，用α-环糊精保护发酵的糊状物，用蛋白酶消化受保护的糊状物，然后过滤，处理 用纤维素酶将所得过滤残渣用乙醇萃取。 具有抗炎作用的花色素肽衍生物用于医药，化妆品，日常用品等。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2011087501A

公开(公告)日：2011-05-06

申请号：JP2009242929

申请日：2009-10-22

申请人： Anri Japan:Kk ,  Bihadaclub Ltd ,  株式会社安理ジャパン ,  美肌倶楽部有限会社

发明人： ITABASHI TAKAKO ,  FUTAMURA YOSHIHIRO

IPC分类号： C12P21/06 ,  A61K8/64 ,  A61Q90/00

摘要： PROBLEM TO BE SOLVED: To provide a method for producing tetrapeptide having nail keratin increasing action with weak side effects.
SOLUTION: A tetrapeptide having nail keratin increasing action is a peptide having a Cys-His-Arg-Cys structure of L-amino acids and linked by a peptide bond. Further, the method for producing the tetrapeptide includes the step for fermenting a composition, which is prepared by adding 0.5-2 pts.wt. of royal jelly and 0.002-0.02 pts.wt. of Monascaceae to 1 pts.wt. of an egg membrane obtained from a Gadus macrocephalus Tilesius, a Gadidae or a Clupeidae, and adding protease to the resulting fermented composition in an amount of 0.03-0.5 times before heating the fermented composition. Furthermore, this tetrapeptide is used as the effective component of a food preparation, cosmetics, or a medical preparation, and also used in an adhesive of an artificial nail or a manicure liquid.
COPYRIGHT: (C)2011,JPO&INPIT

摘要翻译： 待解决的问题：提供具有弱角化作用的具有指甲角蛋白增加作用的四肽的制备方法。 解决方案：具有指甲角蛋白增加作用的四肽是具有L-氨基酸的Cys-His-Arg-Cys结构并通过肽键连接的肽。 此外，生产四肽的方法包括发酵组合物的步骤，其通过加入0.5-2重量份 的蜂王浆和0.002-0.02磅 的Monascaceae到1磅重 从Gadus macrocephalus Tilesius，Gadidae或Clupeidae获得的蛋膜，并在加热发酵的组合物之前以0.03-0.5倍的量向所得发酵组合物中加入蛋白酶。 此外，该四肽用作食品制剂，化妆品或医疗制剂的有效成分，也用于人造指甲或修指甲液的粘合剂中。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2011042599A

公开(公告)日：2011-03-03

申请号：JP2009190598

申请日：2009-08-20

申请人： Anri Japan:Kk ,  株式会社安理ジャパン

发明人： NIMURA TSUYOSHI ,  NIMURA AMI

IPC分类号： C07F9/6596 ,  A23L1/30 ,  A61K31/11 ,  A61P31/12

CPC分类号： Y02A50/385

摘要： PROBLEM TO BE SOLVED: To provide a method for producing a lignin derivative that exhibits an excellent antiviral action with little side effects. SOLUTION: The lignin derivative exhibiting an excellent antiviral action with little side effects is one that exhibits an antiviral action and has an intramolecular cyclic structure. The derivative is composed of persimmon leaf-originated lignin and, bonded thereto, hydroxyapatite and chlorine. The production method thereof comprises the steps of adding hydroxyapatite and Monascus pilosus to a powder of a persimmon leaf followed by fermentation, adding diluted hydrochloric acid to the thus-obtained fermentation liquid followed by filtration, and subsequently subjecting the thus-obtained filtrate to alkali reduction. The main steps are the fermentation step by Monascus pilosus, the hydrochloric acid addition step and the reduction step. By these steps, calcium, phosphoric acid and chlorine stably bond to lignin. COPYRIGHT: (C)2011,JPO&INPIT

摘要翻译： 待解决的问题：提供一种具有优异的抗病毒作用并且副作用小的木质素衍生物的制造方法。 解决方案：具有优异的抗病毒作用的少量副作用的木质素衍生物是表现出抗病毒作用并具有分子内环状结构的木质素衍生物。 该衍生物由柿叶起源的木质素组成，并与其键合羟基磷灰石和氯。 其制造方法包括将羟基磷灰石和红曲霉添加到柿叶粉末中，然后发酵，向得到的发酵液中加入稀盐酸，过滤后，将得到的滤液进行碱还原 。 主要步骤是红曲霉发酵步骤，盐酸添加步骤和还原步骤。 通过这些步骤，钙，磷酸和氯稳定地键合到木质素上。 版权所有（C）2011，JPO＆INPIT