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    Stick type topical formulation containing corticosteroid
    1.
    发明专利
    Stick type topical formulation containing corticosteroid 审中-公开
    包含角质形成剂的STICK型局部制剂

    公开(公告)号：JP2011241211A

    公开(公告)日：2011-12-01

    申请号：JP2011107278

    申请日：2011-05-12

    申请人： Jagotec Ag ,  ヤーゴテック アクチェンゲゼルシャフトJagotec Ag

    发明人： LINDAHL AKE ,  GULLBERG JOHAN

    IPC分类号： A61K31/573 ,  A61K9/00 ,  A61K47/06 ,  A61K47/10 ,  A61K47/44 ,  A61M35/00 ,  A61P17/00 ,  A61P17/06 ,  A61P37/08

    CPC分类号： A61K9/06 ,  A61K9/0014 ,  A61K31/573 ,  A61K47/06 ,  A61K47/10 ,  A61K47/44

    摘要： PROBLEM TO BE SOLVED: To provide a solid stick topical composition containing a corticosteroid.SOLUTION: There is provided a solid stick topical composition comprising a corticosteroid formulation. The solid stick including an outer protective covering also includes: at least one wax present in an amount sufficient such that the stick is solid at 25°C; propyleneglycol in an amount of 5 to 20 wt.%; and an emulsifier present in an amount of 0.2 to 2.0 wt.% based on the total weight of the composition to emulsify the propyleneglycol and petrolatum. The solid stick is contained in a protective covering so that during application it does not come into contact with the hand holding the stick.

    摘要翻译： 待解决的问题：提供含有皮质类固醇的固体棒局部组合物。 提供了包含皮质类固醇制剂的固体棒局部组合物。 包括外部保护性覆盖物的固体棒还包括：至少一种蜡的存在量足够使得该棒在25℃下是固体的; 丙二醇，其量为5至20重量％; 和基于组合物的总重量以0.2至2.0重量％的量存在的乳化剂以乳化丙二醇和凡士林。 固体棒包含在保护层中，使得在施加期间它不会与握住棒的手接触。 版权所有（C）2012，JPO＆INPIT

    Method and device for manufacturing centered compression coating tablet
    2.
    发明专利
    Method and device for manufacturing centered compression coating tablet 审中-公开
    用于制造中心压缩涂层片的方法和装置

    公开(公告)号：JP2014054673A

    公开(公告)日：2014-03-27

    申请号：JP2013226192

    申请日：2013-10-31

    申请人： Jagotec Ag ,  ヤゴテック アーゲー

    发明人： VERGNAULT GUY ,  GRENIER PASCAL

    IPC分类号： B30B11/00 ,  A61K9/28 ,  B30B11/08

    CPC分类号： B30B11/34

    摘要： PROBLEM TO BE SOLVED: To improve the centering of a core of a compression coating tablet.SOLUTION: A pin punch assembly is positioned so as to contact with a top portion of bottom fill powder 19 in a metal mold 17. A roll 13 applies pressure on a protrusion 11 on a pin with a non-punching end of the pin 3 as a fixed position. The pressure compresses a spring 9 so as to project out the pin from a housing, by moving the pin to the housing 1. When the pin moves, an impression or a cup is punched and put in a bottom fill. The size of the impression directly depends on the size of the pin. The depth of the impression directly depends on the height of the protrusion positioned at the top portion of the pin. Next, the pin goes out from the roll, and returns to an original position by action of the spring and a key 5 intercepting the pin at this position.

    摘要翻译： 要解决的问题：改善压缩涂布片芯的定中心。解决方案：针冲头组件定位成与金属模具17中的底部填充粉末19的顶部接触。辊13施加压力 在销的突起11上，销3的非冲孔端作为固定位置。 压力压缩弹簧9，以便通过将销移动到壳体1而将销从壳体突出出来。当销移动时，打印印模或杯子并将其放入底部填充物中。 印象的大小直接取决于针的大小。 印模的深度直接取决于位于销的顶部的突起的高度。 接下来，销从辊中脱出，并且通过弹簧的作用返回到原来的位置，以及在该位置处截取销的键5。

    Drug dispensing container and drug inhaling device
    8.
    发明专利
    Drug dispensing container and drug inhaling device 有权
    药物分配容器和药物吸入装置

    公开(公告)号：JP2007105476A

    公开(公告)日：2007-04-26

    申请号：JP2006277905

    申请日：2006-10-11

    申请人： Jagotec Ag ,  ヤゴテック アーゲー

    发明人： EGGIMANN THOMAS ,  GYIMOTHY GABOR

    IPC分类号： A61M15/00 ,  B65D83/06

    CPC分类号： A61M15/0025 ,  A61M15/003 ,  A61M15/0045 ,  A61M15/0065

    摘要： PROBLEM TO BE SOLVED: To provide a drug dispensing container, giving a dose to a patient only when the dispensing container is placed in a correct positional direction. SOLUTION: This drug dispensing container includes: a housing for storing a drug; a cap connected to the housing; and a gravity actuated lock device for locking the cap, wherein when the container is held in a first directional position, the container is in the non-locked state, and when the container is tilted or rotated, the container is locked by the gravity. A lock device includes: a first lock element connected to a cap, and moved according to the cap in the housing; and a second lock element moved on the contour part formed on the inner surface of the housing by the action of gravity to engage with the first lock element in response to tilting or rotary movement of the container dislocated from the first directional position. The second lock element is formed of material freely moved on receiving the action of gravity even in the presence of electrostatic field. COPYRIGHT: (C)2007,JPO&INPIT

    摘要翻译：

    要解决的问题：本发明提供一种药物分配容器，给予的剂量仅当所述分配容器被放置在正确的位置方向上的患者。 解决方案：该药物分配容器包括：用于储存药物的壳体; 连接到房屋的帽子; 和重力致动锁定装置用于锁定所述盖，其中，当所述容器中的第一方向的位置被保持，所述容器处于非锁定状态，并且当容器被倾斜或旋转时，容器通过重力锁定。 锁定装置包括：第一锁定元件，连接到盖子，并且根据盖子在壳体中移动; 和形成在所述壳体通过重力的作用的内表面上的轮廓部分移动的第二锁元件与所述第一锁定元件接合，响应于倾斜或从第一定向位置错位容器的旋转运动。 第二锁定元件由在静电场的存在下接受重力作用而自由移动的材料形成。 版权所有（C）2007，JPO＆INPIT

    Controlled-release formulations for oral dosage comprising core layer and one or more barrier layers
    10.
    发明专利
    Controlled-release formulations for oral dosage comprising core layer and one or more barrier layers 有权
    用于包含核心层和一个或多个障碍层的口服剂量的控制释放配方

    公开(公告)号：JP2014114323A

    公开(公告)日：2014-06-26

    申请号：JP2014031474

    申请日：2014-02-21

    申请人： Jagotec Ag ,  ヤゴテック アーゲー

    发明人： GUY VERGNAULT ,  GRENIER PASCAL ,  ALAIN NHAMIAS

    IPC分类号： A61K9/32 ,  A61K9/48 ,  A61K31/4422 ,  A61K47/32 ,  A61K47/38 ,  A61P9/10 ,  A61P9/12

    CPC分类号： A61K9/2886 ,  A61K9/0053 ,  A61K9/2027 ,  A61K9/2086 ,  A61K9/2846 ,  A61K9/2866 ,  A61K31/4422

    摘要： PROBLEM TO BE SOLVED: To provide: a controlled-release formulation that releases an active agent with an ascending release rate in response to the change in pH when it reaches gastrointestinal tract after its administration to a patient; a method of producing the same; and a method of using the same.SOLUTION: Solid controlled-release multilayer formulations for oral dosage contains: a core layer comprising one or more active agents and one or more enteric materials; and two or more barrier layers comprising one or more swellable, erodible, or gellable polymers, wherein the one of the barrier layers is provided on the upper side of the core layer and the other(s) thereof are/is provided on the lower side of the core layer.

    摘要翻译： 要解决的问题：提供：控制释放制剂，其在施用于患者后达到胃肠道时响应于pH变化而释放具有上升释放速率的活性剂; 其制造方法; 和其使用方法。解决方案：用于口服剂量的固体控释多层制剂包含：包含一种或多种活性剂和一种或多种肠溶性物质的核心层; 以及包含一种或多种可溶胀，可侵蚀或可凝胶化聚合物的两个或更多个阻挡层，其中所述阻挡层中的一个设置在芯层的上侧，并且其另一个设置在下侧 的核心层。