公开(公告)号：JP2012153619A

公开(公告)日：2012-08-16

申请号：JP2011011797

申请日：2011-01-24

申请人： Bedaring Japan:Kk ,  Nippon Zettoc Co Ltd ,  Toyo Seito Kk ,  日本ゼトック株式会社 ,  東洋精糖株式会社 ,  株式会社Bedaring−Japan

发明人： KAWABATA AYA ,  YASUMURO MISAO ,  SUGIYAMA SHINJI ,  SHIMOIDA TAKASHI ,  KOTANI YASUHIRO

IPC分类号： A61K8/60 ,  A61K31/7032 ,  A61P1/02 ,  A61Q11/00

摘要： PROBLEM TO BE SOLVED: To provide a composition for the oral cavity, which quickly feeds moisture into the dried oral cavity to alleviate the dried conditions in the oral cavity, quickly infiltrates the moisture into phlegm and dirt stuck while being dried in the oral cavity, facilitates their cleaning, further, prevents inflammatory disease in the oral cavity, particularly, periodontal disease, and further can inhibit/alleviate the conditions.SOLUTION: The composition for the oral cavity includes glyceryl glucoside. The composition for the oral cavity is a composition for treating or preventing xerosis in the oral cavity. The composition for the oral cavity is an inflammation inhibitor in the oral cavity. The composition for the oral cavity is a treatment agent or a preventive agent for periodontal disease and the related disorder thereof. The composition for the oral cavity includes glyceryl glucoside of 0.01 to 20 mass%.

摘要翻译： 要解决的问题：为了提供一种用于口腔的组合物，该组合物将干燥的口腔内的水分迅速送入，以减轻口腔中的干燥状况，迅速将水分渗透到痰中，同时在 口腔，便于清洗，进一步防止口腔炎症，特别是牙周病，进一步抑制/缓解病情。 解决方案：口腔用组合物包括甘油基葡糖苷。 用于口腔的组合物是用于治疗或预防口腔干燥症的组合物。 用于口腔的组合物是口腔中的炎症抑制剂。 口腔用组合物是牙周病的治疗剂或预防剂及其相关病症。 口腔用组合物含有0.01〜20质量％的甘油基糖苷。 版权所有（C）2012，JPO＆INPIT

公开(公告)号：JP2008072916A

公开(公告)日：2008-04-03

申请号：JP2006253327

申请日：2006-09-19

申请人： Rikomu:Kk ,  Toyo Seito Kk ,  東洋精糖株式会社 ,  株式会社リコム

发明人： TAKADO TAKETOSHI ,  IIDA SUMIHISA ,  KURIHARA SHOICHI

IPC分类号： C12P19/04 ,  A23K1/16 ,  A23L1/308 ,  A61K8/73 ,  A61K47/36

摘要： PROBLEM TO BE SOLVED: To provide vegetable chitosan (highly dispersible vegetable chitosan) having improved dispersability in water, and to provide a method for producing the same.
SOLUTION: Highly dispersible vegetable chitosan can be produced efficiently by treating vegetable chitosan with a glycosyltransferase (for example, cyclodextrin glucanotransferase). Enzymatic treatment is, preferably, carried out in the coexistence of a sugar donor. The vegetable chitosan is, preferably, obtained by deacetylating chitin contained in carpophores or mycelia of Basidiomycetes, such as Lentinula edodes, Flammulina velutipes, Agaricus bisporus, Grifola frondosa, Pleurotus eryngii, or Lyophyllum shimeji.
COPYRIGHT: (C)2008,JPO&INPIT

摘要翻译： 待解决的问题：提供具有改善的在水中的分散性的植物壳聚糖（高分散性植物壳聚糖），并提供其制备方法。 解决方案：通过用糖基转移酶（例如，环糊精葡聚糖转移酶）处理植物壳聚糖，可以有效地生产高分散性植物壳聚糖。 酶促治疗优选在糖供体共存下进行。 植物壳聚糖优选通过脱乙酰化包含在担架担子菌菌丝体中的壳多糖，例如香菇，Flammulina velutipes，双孢蘑菇，Grifola frondosa，Pleurotus eryngii或Lyophyllum shimeji。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2004059522A

公开(公告)日：2004-02-26

申请号：JP2002221601

申请日：2002-07-30

申请人： Fancl Corp ,  Toyo Seito Kk ,  東洋精糖株式会社 ,  株式会社ファンケル

发明人： YOSHIZUMI KAZUMA ,  TAKADO TAKETOSHI ,  YUMOTO TAKASHI ,  SHIMOI KAYOKO

IPC分类号： A23L1/30 ,  A61K31/7048 ,  A61P9/10 ,  A61P35/00

摘要： PROBLEM TO BE SOLVED: To provide a long-acting rutin preparation capable of keeping a quercetin conjugate concentration in blood over a long time and decreasing administration frequency and an oral composition, a food or medicine containing the preparation. SOLUTION: The long-acting rutin preparation comprises an enzyme-treated rutin or a mixture of the enzyme-treated rutin with rutin. The preparation can keep the quercetin conjugate concentration in the blood for a long time and is useful as an oral composition, a food or a medicine for prophylaxis/treatment of diseases such as cancers, arteriosclerosis and ischemic heart diseases. COPYRIGHT: (C)2004,JPO

摘要翻译： 待解决的问题：提供能够长时间保持血液中槲皮素缀合物浓度并降低给药频率和口服组合物的长效芦丁制剂，含有该制剂的食品或药物。 解决方案：长效芦丁制剂包含酶处理的芦丁或经酶处理的芦丁与芦丁的混合物。 该制剂可以长时间保持血液中的槲皮素缀合物浓度，并且可用作口服组合物，食品或用于预防/治疗诸如癌症，动脉硬化和缺血性心脏病的疾病的药物。 版权所有（C）2004，JPO

公开(公告)号：JPS5920222A

公开(公告)日：1984-02-01

申请号：JP13016082

申请日：1982-07-26

申请人： Toyo Seito Kk

发明人： OOE YOSHIHIRO ,  TAKAYA IKUO

IPC分类号： A61K36/48 ,  C07H15/256

摘要： PURPOSE: To separate and purify easily and efficiently glycyrrhizin, by bringing an extract solution of a licorice into contact with a synthetic resin adsorbent, weakly adsorbing the glycyrrhizin on the synthetic resin, strengthening the adsorption by treatment with an acid, washing the adsorbed glycyrrhizin with water, and eluting the glycyrrhizin with an organic solvent.
CONSTITUTION: An extract solution of a licorice containing glycyrrhizin is brought into contact with a medium polar or nonpolar synthetic resin adsorbant having the giant network structure under warming preferably at 50W60°C to adsorb weakly the glycyrrhizin on the synthetic resin adsorbent. The adsorbent is then treated with an inorganic or organic acid to strengthen the adsorption of the glycyrrhizin. The adsorbent is then washed with water to flow out impurities and the acid used in the above-mentioned step. The adsorbed glycyrrhizin is then eluted with a hydrous organic solvent or organic solvent. A styrene-divinylbenzene type polymer having 250W800m
2 /g specific surface area, 40W100Å average pore diameter and 30W55vol% porosity may be cited as the above-mentioned nonpolar adsorbent.
COPYRIGHT: (C)1984,JPO&Japio

摘要翻译： 目的：通过将甘草的提取液与合成树脂吸附剂接触，将甘草甜素弱吸附在合成树脂上，通过酸处理加强吸附，用吸附的甘草酸洗涤吸附的甘草酸，分离纯化甘草甜素 水，并用有机溶剂洗脱甘草甜素。 构成：将含有甘草甜素的甘草的提取液与具有巨型网状结构的中等极性或非极性合成树脂吸附剂接触，优选在50-60℃下，以弱吸附合成树脂吸附剂上的甘草甜素。 然后用无机或有机酸处理吸附剂，以加强甘草甜素的吸附。 然后用水洗涤吸附剂以流出上述步骤中使用的杂质和酸。 然后用含水有机溶剂或有机溶剂洗脱吸附的甘草酸。 可以列举具有250-800m 2 / g比表面积，40-100A平均孔径和30-55vol％孔隙率的苯乙烯 - 二乙烯基苯型聚合物作为上述非极性吸附剂。

公开(公告)号：JP2013056864A

公开(公告)日：2013-03-28

申请号：JP2011197248

申请日：2011-09-09

申请人： Toyo Seito Kk ,  東洋精糖株式会社

发明人： AIZAWA YASUSHI ,  TAKADO TAKETOSHI ,  IIDA SUMIHISA

IPC分类号： A61K8/60 ,  A61K8/81 ,  A61Q19/00

摘要： PROBLEM TO BE SOLVED: To provide a substance capable of exhibiting an excellent effect as an additive for a skin external preparation.SOLUTION: There is provided a mixture of cationized glyceryl glucoside expressed by general formula (I). (In the formula, GG represents a glyceryl glucoside residue; R, Rand Reach represents a hdyrocarbyl group; X represents a counter anion; and n denotes an integer of 1 to 3.) The mixture of the above cationized glyceryl glucoside is used as an additive for a skin external preparation. There is also provided a skin external preparation which contains the cationized glyceryl glucoside expressed by general formula (I).

摘要翻译： 待解决的问题：提供能够表现出作为皮肤外用剂的添加剂的优异效果的物质。 提供由通式（I）表示的阳离子化甘油基葡糖苷的混合物。 （式中，GG表示甘油基糖苷残基，R 2 ，R 3 各自表示羟基; X表示抗衡阴离子; n表示1〜3的整数。）上述阳离子化甘油基葡糖苷的混合物用作皮肤外用剂的添加剂。 还提供了含有由通式（I）表示的阳离子化甘油基葡糖苷的皮肤外用剂。 版权所有（C）2013，JPO＆INPIT

公开(公告)号：JP2012082408A

公开(公告)日：2012-04-26

申请号：JP2011203068

申请日：2011-09-16

申请人： Bedaring Japan:Kk ,  Sanwa Chemical Industry Co Ltd ,  Toyo Seito Kk ,  三和化学工業株式会社 ,  東洋精糖株式会社 ,  株式会社Bedaring−Japan

发明人： NAKAI MASATO ,  KOTANI YASUHIRO ,  SHIMOIDA TAKASHI

IPC分类号： C11D9/04 ,  A61K8/36 ,  A61K8/60 ,  A61Q19/10 ,  C11D9/26 ,  C11D10/06

摘要： PROBLEM TO BE SOLVED: To provide a transparent solid soap composition that is excellent in moisture feeling after washing, transparency and bubbling properties, is less likely to be bleached to maintain its excellent transparency under a storage condition, is less likely to be reduced in its soap amount when dried, is less likely to become cloudy to maintain its excellent transparency under a use condition, and is less likely to be reduced in its soap amount due to appearance change such as stickiness, perspiration and melting-away.SOLUTION: The transparent solid soap composition comprises an aliphatic soap (A), sugar (B) used as a clarifying agent, glucopyranosylglycerol (C) used as a clouding inhibitor, and water (D).

摘要翻译： 待解决的问题：提供一种透明固体皂组合物，其在洗涤后的湿感，透明性和起泡性能优异，在保存条件下不太可能漂白以保持其优异的透明度，不太可能 干燥时的皂量减少，在使用条件下不太可能变得浑浊，保持其优异的透明性，并且由于诸如粘性，出汗和熔化的外观变化而不太可能减少其皂量。 透明固体皂组合物包含用作澄清剂的脂族皂（A），糖（B），用作遮光抑制剂的吡喃葡糖基甘油（C）和水（D）。 版权所有（C）2012，JPO＆INPIT

公开(公告)号：JP2009209066A

公开(公告)日：2009-09-17

申请号：JP2008052355

申请日：2008-03-03

申请人： Toyo Seito Kk ,  東洋精糖株式会社

发明人： YAMAMOTO TATSUHIKO ,  IIDA SUMIHISA

IPC分类号： A61K31/7048 ,  A23K1/16 ,  A23L1/30 ,  A61K8/49 ,  A61K8/60 ,  A61K31/353 ,  A61P3/06 ,  A61P7/04 ,  A61P9/00 ,  A61P9/10 ,  A61P9/12 ,  A61P25/04 ,  A61P29/00 ,  A61Q19/00

摘要： PROBLEM TO BE SOLVED: To provide a hesperetin composition that exhibits improved bioabsorbability of hesperetin and is suitable for oral ingestion.
SOLUTION: The hesperetin composition exhibits excellent bioabsorbability of hesperetin as it comprises enzyme-treated hesperidin and hesperetin. The enzyme-treated hesperidin is preferably a mixture of α-glucosylhesperidin with either or both of hesperidin and 7-glucosylhesperetin. The hesperetin composition preferably contains hesperetin in an amount of 1-15 pts.wt. based on 100 pts.wt. of the enzyme-treated hesperidin.
COPYRIGHT: (C)2009,JPO&INPIT

摘要翻译： 要解决的问题：提供表现出改善的橙皮素生物吸收性的橙皮素组合物，并且适合于口服摄取。 解决方案：橙皮素组合物显示出优异的橙皮素生物吸收性，因为它包括酶处理的橙皮苷和橙皮素。 酶处理的橙皮苷优选为α-葡萄糖苷基与橙皮苷和7-葡萄糖基苯乙烯之一或两者的混合物。 橙皮素组合物优选含有1-15重量份的橙皮素 基于100重量 的酶处理橙皮苷。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008271836A

公开(公告)日：2008-11-13

申请号：JP2007118532

申请日：2007-04-27

申请人： Toyo Seito Kk ,  東洋精糖株式会社

发明人： YAMAMOTO TATSUHIKO ,  IWAMOTO YUTAKA ,  IIDA SUMIHISA

IPC分类号： A23L27/30 ,  A23F3/16 ,  A23L2/02 ,  A23L2/60

摘要： PROBLEM TO BE SOLVED: To provide a clathrate compound capable of heightening absorbability when being taken orally and improving its bioavailability, by raising the water solubility of hesperetin having a sweetness degree of a hundred or more times that of simple sugar. SOLUTION: The hesperetin is dissolved in an alkaline water solution, and a solution is added to the solution, which is obtained by warming and dissolving β-cyclodextrin and/or branched β-cyclodextrin. Then, the mixture is neutralized by a sulfuric acid solution, microfiltrated, and then freeze-dried, thereby obtaining powder of clathrate. In this clathrate processing, the ratio of the β-cyclodextrin and/or branched β-cyclodextrin to the hesperetin is 1.5-2.1 mol to 1 mol. COPYRIGHT: (C)2009,JPO&INPIT

摘要翻译： 待解决的问题：通过提高甜味度为单糖的百倍或更多倍的橙皮素的水溶性，提供能够在口服时提高吸收性并提高其生物利用度的包合物化合物。 解决方案：将橙皮素溶解在碱性水溶液中，并通过加热和溶解β-环糊精和/或支链β-环糊精而获得的溶液中加入溶液。 然后，将混合物用硫酸溶液中和，微滤，然后冷冻干燥，从而得到包合物粉末。 在这种包合处理中，β-环糊精和/或支链β-环糊精与橙皮素的比例为1.5-2.1mol至1mol。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2007039419A

公开(公告)日：2007-02-15

申请号：JP2005228283

申请日：2005-08-05

申请人： Toyo Seito Kk ,  東洋精糖株式会社

发明人： TAKADO TAKETOSHI ,  IWAMOTO YUTAKA ,  IIDA SUMIHISA ,  YUMOTO TAKASHI

IPC分类号： A61K31/7048 ,  A23L1/30 ,  A61K8/60 ,  A61K47/36 ,  A61P3/06 ,  A61P7/04 ,  A61P9/00 ,  A61P39/00 ,  A61P39/06

摘要： PROBLEM TO BE SOLVED: To provide a composition having improved solubility of naringin in water compared with conventional composition, i.e. provide a water-soluble naringin composition. SOLUTION: The water-soluble naringin composition contains naringin in combination with α-glucosylhesperidin and β-monoglucosylhesperetin. The sum theα-glucosylhesperidin and β-monoglucosylhesperetin (total hesperidin amount) is preferably 0.01-5 pts.wt. in terms of hesperidin based on 1 pt.wt. of naringin. COPYRIGHT: (C)2007,JPO&INPIT

摘要翻译： 要解决的问题：提供与常规组合物相比，柚皮苷在水中的溶解度提高的组合物，即提供水溶性柚皮苷组合物。 解决方案：水溶性柚皮苷组合物含有柚皮苷与α-葡萄糖苷和β-单葡萄糖基苯吡啶的组合。 α-葡萄糖苷基和β-单葡萄糖基苯乙烯（总橙皮苷量）的总和优选为0.01-5重量份。 以橙皮苷为基础，1重量％ 的柚皮苷。 版权所有（C）2007，JPO＆INPIT

公开(公告)号：JP2005343865A

公开(公告)日：2005-12-15

申请号：JP2004168631

申请日：2004-06-07

申请人： Toyo Seito Kk ,  東洋精糖株式会社

发明人： YODA NAOKO ,  IIDA SUMIHISA ,  YUMOTO TAKASHI

IPC分类号： A23L1/30 ,  A23L1/222 ,  A61K31/7048 ,  A61K36/00 ,  A61K36/75 ,  A61P3/02 ,  A61P7/04 ,  A61P9/00 ,  A61P9/14 ,  A61K35/78

摘要： PROBLEM TO BE SOLVED: To obtain a hesperidin composition in which the characteristic smell of an enzyme-treated hesperidin is remarkably reduced. SOLUTION: This low smelling enzyme-treated hesperidin composition is obtained by allowing cyclodextrin glucanotransferase to act on a hesperidin-containing product extracted from lemon in the presence of a glucose-imparting agent, and further treating the product with one or more of porous synthetic adsorbing resins, ion exchange resins, and carbon. A method for producing the composition and a drink or food, a cosmetic or a medicine containing the composition are disclosed. The hesperidin-containing product is slurry, and it is preferable that the hesperidin-containing product is heated at a temperature of 75 to 100°C for 15 to 60 minutes under the ordinary pressure prior to an enzymatic treatment. It is preferable that the low smelling enzyme-treated hesperidin composition is either of an additive for foods, an additive for cosmetics, and an additive for medicines. COPYRIGHT: (C)2006,JPO&NCIPI

摘要翻译： 待解决的问题：为了获得其中显着降低酶处理的橙皮苷的特征气味的橙皮苷组合物。 解决方案：通过在葡萄糖赋予剂存在下使环糊精葡聚糖转移酶作用于从柠檬提取的含有橙皮苷的产品，并进一步用一种或多种 多孔合成吸附树脂，离子交换树脂和碳。 公开了一种生产该组合物的方法以及含有该组合物的饮料或食品，化妆品或药物。 含有橙皮苷的产品是浆料，优选在酶处理之前，常压下将含橙皮苷的产品在75至100℃的温度下加热15至60分钟。 优选的是，低嗅酶处理的橙皮苷组合物是食品添加剂，化妆品添加剂和药物添加剂。 版权所有（C）2006，JPO＆NCIPI