专利检索 ap:("アムイリス, インコーポレイテッド") AND inv:"ドリングレンン" 第 1 页

1.

发明专利
The method for purifying a biological organic compounds from a fermentation broth containing a surfactant by a temperature-induced phase inversion 审中-公开

公开(公告)号：JP2013534144A

公开(公告)日：2013-09-02

申请号：JP2013524893

申请日：2011-08-12

申请人： アムイリス, インコーポレイテッド

发明人： タブルピナル , ドリングレンン

IPC分类号： C12P5/00 , C12N1/12 , C12N1/14 , C12N1/20

CPC分类号： C12P5/02 , C11B1/00 , C12P5/007 , Y02E50/343

摘要： Methods and systems for purifying bio-organic compounds are described. In certain embodiments, the methods comprise the steps of (a) providing a composition or an emulsion comprising a surfactant, host cells, an aqueous medium and a bio-organic compound produced by the host cells, wherein the solubility of the surfactant in the aqueous medium decreases with increasing temperature and wherein the temperature of the composition or emulsion is at least about 1° C. below a phase inversion temperature of the composition or emulsion; (b) raising the temperature of the composition or emulsion to at least about 1° C. above the phase inversion temperature; and (c) performing a liquid/liquid separation of the composition to provide a crude bio-organic composition or emulsion.