公开(公告)号：JPH07304658A

公开(公告)日：1995-11-21

申请号：JP10945895

申请日：1995-05-08

申请人： IMMUNO AG

发明人： EIBL JOHANN ,  SCHWARZ HANS PETER ,  SIEKMANN JUERGEN ,  TURECEK PETER

IPC分类号： A61K9/127 ,  A61K9/14 ,  A61K38/43 ,  A61K38/48 ,  A61K38/55 ,  A61P7/02 ,  C12N9/64 ,  C12N9/96 ,  A61K9/19

摘要： PURPOSE: To obtain the subject preparation, containing a protein lipid complex in a vesicular form, subjected to a treatment for the inactivation of potentially present viruses and useful for treating blood coagulation disorders containing a coagulation active protein. CONSTITUTION: This stable virally safe preparation contains a protein bound in and/or on lipid vesicles (preferably a coagulation active protein) and is subjected to a treatment for inactivation of potentially present viruses (preferably heat treatment). The preparation preferably contains a blood coagulation factor of an endogenous or an exogenous blood coagulation, preferably an active type blood coagulation factor (e.g. a vitamin K-dependent protein, IIa factor or VIIa factor). The preparation is useful for intravenous injection.