公开(公告)号：JPS61189267A

公开(公告)日：1986-08-22

申请号：JP2996285

申请日：1985-02-18

申请人： LIGHT OIL UTILIZATION RES ASS

发明人： HOYA TAKAO ,  MOGI HIDENOBU ,  HAYAYAMA HIROSHI

IPC分类号： C07D209/20 ,  C07C67/00 ,  C07C227/00 ,  C07C227/40 ,  C07C229/04

摘要： PURPOSE:To obtain tryptophan from an aqueous solution containing tryptophan together with other amino acids, by contacting the solution with a strongly acidic cation exchange resin beads, desorbing the other amino acids from the resin with an aqueous solution of an acid, etc., and then separating tryptophan with an alkaline aqueous solution. CONSTITUTION:An aqueous solution containing tryptophan together with other amino acids is made to contact with strongly acidic cation exchange resin beads filled in a column to effect the adsorption of tryptophan and a part of the coexisting amino acids, and the resin is made to contact with an aqueous solution of an acid or an inorganic salt to effect the desorption of the adsorbed coexisting amino acids. Thereafter, the adsorbed tryptophan is desorbed with an alkaline aqueous solution, and the desorbed solution is made to contact again with the resin. The adsorption and desorption are repeated to separate the tryptophan in the form of highly concentrated solution. EFFECT:An alkaline aqueous solution having a tryptophan concentration of 3-15wt% and free from impurity amino acid can be produced.