专利检索 ap:("Lonza Ag" OR "ロンザリミテッドLonza Limited") AND inv:"FERNANDO ALBERICIO" 第 1 页

1.

发明专利
Indolesulfonyl protecting groups for protection of guanidyl and amino groups 有权
标题翻译：保护组织和氨基酸组合的保护基团

公开(公告)号：JP2014193872A

公开(公告)日：2014-10-09

申请号：JP2014092764

申请日：2014-04-28

申请人： Lonza Ag , ロンザリミテッドLonza Limited

发明人： MATTHIEU GIRAUD , FERNANDO ALBERICIO , ALBERT ISIDRO LLOBET , MERCEDES ALVAREZ DOMINGO

IPC分类号： C07D209/30 , C07K17/02

CPC分类号： C07D209/30 , Y02P20/55

摘要： PROBLEM TO BE SOLVED: To provide compounds which are useful for the protection of organic compounds comprising at least one guanidino moiety and/or amino group, as protecting reagents in production of compounds; and processes for their preparation and their use as protecting reagents.SOLUTION: The invention relates to indolesulfonyl halogenides of the figure II; preparation processes based on side chain introduction; and introduction to a guanidino group in a peptide side chain.

摘要翻译： 要解决的问题：提供可用于保护包含至少一个胍基部分和/或氨基的有机化合物的化合物作为化合物生产中的保护试剂; 以及它们的制备及其用作保护试剂的方法。解决方案：本发明涉及图II的吲哚磺酰卤; 基于侧链引进的制备工艺; 并引入肽侧链中的胍基。