公开(公告)号：JPS5439028A

公开(公告)日：1979-03-24

申请号：JP10354577

申请日：1977-08-31

申请人： HOKKO CHEM IND CO ,  UBE INDUSTRIES

发明人： NAGAI SHIGEKI ,  HIROTA YOUJIROU ,  YORIE TAKASHI ,  FUJII KATSUTOSHI ,  HIBI TOORU ,  SATOU KATSUMI ,  YAMAMURA HIROSHI ,  WADA TAKUO ,  YAMADA YOSHITAKE

IPC分类号： A01N47/20 ,  A01N37/22 ,  A01N37/26 ,  A01N37/34 ,  A01N37/46 ,  C07C67/00 ,  C07C313/00 ,  C07C323/60

摘要： PURPOSE:Acetanilide derivatives of formula I(R1 is lower alkyl substituted with phenylthio or carboxy lower alkylthio, alkylthiomethyl; R2 is H lower alkyl, cyano lower alkyl, etc.; X is halogen, lower alkyl, nitro, etc.; n is 0,1-3).

公开(公告)号：JPS5312422A

公开(公告)日：1978-02-03

申请号：JP8650576

申请日：1976-07-22

申请人： HOKKO CHEM IND CO ,  UBE INDUSTRIES

发明人： NAGAI SHIGEKI ,  HIROTA YOUJIROU ,  YORIE TAKASHI ,  HIBI TOORU ,  SATOU KATSUMI ,  YAMAMURA HIROSHI ,  WADA TAKUO ,  AOI ISAO

IPC分类号： A01N47/30

摘要： PURPOSE:Fungicides for agriculture and horticulture, containing arylthiourea compounds as active constituents.

公开(公告)号：JPS52108975A

公开(公告)日：1977-09-12

申请号：JP2558176

申请日：1976-03-11

申请人： HOKKO CHEM IND CO ,  UBE INDUSTRIES

发明人： NAGAI SHIGEKI ,  YORIE TAKASHI ,  HIROTA YOUJIROU ,  HIBI TOORU ,  SATOU KATSUMI ,  YAMAMURA HIROSHI ,  WADA TAKUO ,  AOI ISAO

IPC分类号： A01N43/14 ,  C07D309/36

摘要： PURPOSE:Pyrone derivatives of the formula (R is lower alkyl;M is a watersoluble metal atom). For example, 6-methyl-3-(N-phenylcarbamoyl)-4-hydroxypyrone sodium salt may be cited.

公开(公告)号：JPS5270019A

公开(公告)日：1977-06-10

申请号：JP14628275

申请日：1975-12-10

申请人： HOKKO CHEM IND CO ,  UBE INDUSTRIES

发明人： SATOU KATSUMI ,  YAMAMURA HIROSHI ,  WADA TAKUO ,  AOI ISAO ,  NAGAI SHIGEKI ,  HIROTA YOUJIROU ,  HIBI TOORU

IPC分类号： A01N35/04 ,  C07C45/00 ,  C07C49/84 ,  C07C67/00

摘要： PURPOSE:Fungicidal composition containing a phenylacetophenone derivative as active ingredient effective for the control of helminthosporium leaf spot and blast on rice plants and powdery mildew on cucumbers without exerting any damage to applied plants.

公开(公告)号：JPS57116066A

公开(公告)日：1982-07-19

申请号：JP162181

申请日：1981-01-10

申请人： HOKKO CHEM IND CO ,  UBE INDUSTRIES

发明人： NAGAI SHIGEKI ,  HIROTA YOUJIROU ,  YORIE TAKASHI ,  SUGIURA HISAO ,  HIBI TOORU ,  SATOU KATSUMI ,  WADA TAKUO ,  MIYAHARA MASAHIKO

IPC分类号： C07D333/38 ,  A01N43/08 ,  A01N43/10 ,  A01N43/40 ,  A01N57/16 ,  C07D333/00 ,  C07D333/32 ,  C07D409/14 ,  C07F9/165 ,  C07F9/6553

摘要： NEW MATERIAL:A thiophene derivative shown by the formulaI[R1 is lower alkoxyethylcarbonyl, lower halogen-substituted lower alkylcarbonyl (except chloromethylcarbonyl), cycloalkycarbonyl, etc.; R2 is alkyl, lower alkenyl, lower alkynyl, when R2 is higher alkyl, R1 may be lower alkylcarbonyl, lower alkoxymethylcarbonyl, etc.]. EXAMPLE:3,4-Di-(2'-ethoxyethylcarbonyloxy)-2,5-dicarbethoxy-thiophene. USE:An agricultural and gardening fungicide. Exhibiting widely controlling effect on heliminthospororium of rice plant, late blight of tomato, BAKANAE diesease of rice plant, leaf mold of tomato, etc. PROCESS:A compound shown by the formulaIis obtained by a method shown by the reaction formula.

公开(公告)号：JPS57116064A

公开(公告)日：1982-07-19

申请号：JP161981

申请日：1981-01-10

申请人： HOKKO CHEM IND CO ,  UBE INDUSTRIES

发明人： NAGAI SHIGEKI ,  HIROTA YOUJIROU ,  YORIE TAKASHI ,  SUGIURA HISAO ,  HIBI TOORU ,  SATOU KATSUMI ,  WADA TAKUO ,  MIYAHARA MASAHIKO

IPC分类号： A01N47/06 ,  A01N43/08 ,  A01N43/10 ,  A01N47/10 ,  A01N47/18 ,  A01N57/16 ,  C07D333/00 ,  C07D333/32 ,  C07D333/38 ,  C07D409/12 ,  C07F9/165 ,  C07F9/6553

摘要： NEW MATERIAL:A thiophene derivative shown by the formulaI(X is H, alkyl metal atom, lower alkylcarbonyl, lower alkoxy lower alkylcarbonyl, lower alkylthio lower alkylcarbonyl, halogen-substituted lower alkylcarbonyl, cycloalkylcarbonyl, etc.; R is lower alkyl). EXAMPLE:3,4-Dihydroxy-2-cyano-5-carbethoxy-thiophene. USE:An agricultural and gardening fungicide. Exhibiting a controlling effect on blast of rice plant, helminthosporium leaf spot of rice plant, late blight of tomato, stem rot of a kidney bean, etc. PROCESS:As shown by the reaction formula, for example, ethyl oxalate is reacted with ethyl ester of cyanomethyl thioglycol and sodium ethylate, to give precipitated sodium salt, which is subjected to acid precipitation with hydrochloric acid. A compound shown by the formulaIis obtained by recrystallization of the resulted compound with acetic acid.

公开(公告)号：JPS56161381A

公开(公告)日：1981-12-11

申请号：JP6440780

申请日：1980-05-15

申请人： UBE INDUSTRIES ,  HOKKO CHEM IND CO

发明人： NAGAI SHIGEKI ,  HIROTA YOUJIROU ,  YORIE TAKASHI ,  SUGIURA HISAO ,  HIBI TOORU ,  SATOU KATSUMI ,  WADA TAKUO ,  MIYAHARA MASAHIKO

IPC分类号： A01N43/08 ,  C07D307/52 ,  C07D307/68

摘要： NEW MATERIAL:An anilide derivative of formula I (X is lower alkyl; m is O or an integer 1 or 2; R is alkyl, alkoxyalkyl, alkylthioalkyl, furyl or phenyl which may be substituted by lower alkyl, lower alkoxyl or halogen). EXAMPLE:N-Furfuryl-2-fur-2',6'-dimethylanilide. USE:An agricultural and horticultural germicide having a control activity against blast of rice plants, late blight of tomatoes, downy mildew of cucumbers, etc. PROCESS:A compound of formula II is reacted with a compound of formula III to give the compound of formula I. Specifically, for example, N-furfuryl-2,6-dimethylamiline and tire specithylamine are dissolved in benzene, and 2-furoyl chloride is dropped and reacted therewith. After cooling, the reaction mixture is dehydrated and concentrated to afford the exemplified compound.

公开(公告)号：JPS56161360A

公开(公告)日：1981-12-11

申请号：JP6440680

申请日：1980-05-15

申请人： UBE INDUSTRIES ,  HOKKO CHEM IND CO

发明人： NAGAI SHIGEKI ,  HIROTA YOUJIROU ,  YORIE TAKASHI ,  SUGIURA HISAO ,  HIBI TOORU ,  SATOU KATSUMI ,  WADA TAKUO ,  MIYAHARA MASAHIKO

IPC分类号： A01N47/20 ,  A01N37/22 ,  A01N37/24 ,  A01N43/08 ,  A01N43/10 ,  C07C67/00 ,  C07C231/00 ,  C07C233/00 ,  C07C233/65 ,  C07C235/16 ,  C07C235/68 ,  C07C239/00 ,  C07C271/04 ,  C07C325/00 ,  C07C333/08 ,  C07D333/24

摘要： NEW MATERIAL:An anilide derivative of formula I (R1 i H or lower alkyl; R2 is thienyl, Cl, phenyl, etc.; X and Y are lower alkyl; m is an integer 0,1 or 2; n is an integer 0 or 1). EXAMPLE:N-Benzyl-2',6'-dimethyl-2-thiophenecarbox anilide. USE:An agricultural and horticultural germicide having a control activity against blast and helminthosporium leaf spot of rice plants. PROCESS:A compound of formula II is reacted with a compound of formula III to give the compound of formula I.

公开(公告)号：JPS5622704A

公开(公告)日：1981-03-03

申请号：JP9870079

申请日：1979-08-03

申请人： UBE INDUSTRIES

发明人： KAWAZOE HIROICHI ,  NAGAI SHIGEKI ,  NAGAI HIROFUMI ,  HIROTA YOUJIROU ,  YORIE TAKASHI ,  IIDA SEIJI ,  HIBI TOORU

IPC分类号： A01N37/52 ,  A01N20060101

摘要： NEW MATERIAL:An amidine compound expressed by the formula (Y is H or lower alkyl; R and R are alkyls or alkenyls; R is alkyl, alkynyl, benzyl, chlorosubstituted benzyl, cyano, cyanoalkyl, alkoxycarbonylmethyl, phenoxyethyl, alkyl- substituted phenoxyethyl, etc.; X is inorganic or organic acid; n is 0 or 1). EXAMPLE:N,N-Diethyl-N'-isopropylbenzamidine. USE:An agricultural and horticultural germicide having remarkable control effects, particularly on powdery mildew of various crops, even in a lower amount than the commercially available drug, and on pathogenic fungi of gray mold, anthracnose, blast, etc. with very little phytotoxicity to crops and very low toxicity to men and cattle. PROCESS:A mixture of N,N-diethylbenzamidine with isopropyl iodide is heated for 1hr. After allowing to cool, the mixture is made strongly alkaline with a 25% aqueous solution of NaOH to afford the compound of the formula.

公开(公告)号：JPS55105603A

公开(公告)日：1980-08-13

申请号：JP1283079

申请日：1979-02-08

申请人： UBE INDUSTRIES

发明人： KAWAZOE HIROICHI ,  NAGAI SHIGEKI ,  NAGAI HIROFUMI ,  HIROTA YOUJIROU ,  YORIE TAKASHI ,  IIDA SEIJI ,  HIBI TOORU

IPC分类号： A01N37/52

摘要： NEW MATERIAL:An amidine compound of the formula (Q is phenyl or naphthyl which may have 1-3 substituents, e.g. a lower alkyl group; R1 and R2 are alkyl, alkenyl, cycloalkyl or phenyl groups, or may form with the N atom to which they are attached a 5- to 7-membered saturated alicylic ring, wherein another O atom may be a constituent atom and 1-2 CH3 groups may be contained; X is inorganic or organic acid; n is 0, 1, or 2). EXAMPLE:N,N-Diethylbenzamidine. USE:Agricultural and horticultural germicides having powerful control effects on various pathogenic germs, particularly powdery mildew, of crops, with low damage and toxicity. PROCESS:A Grignard reagent is reacted with a secondary amine in a solvent, and the reaction product is reacted with a nitrile under heating. The resulting product is decomposed with ammonium chloride, and treated with a strong alkali to give the objective compound of the formula.