摘要:
PROBLEM TO BE SOLVED: To provide improved methods and devices for transdermal delivery of agents such as drugs and monitoring of analytes such as blood components.SOLUTION: The invention provides a transdermal drug delivery device for forming a drug delivery patch system comprising: an actuator (comprising an outer body, a controller board, and an interface connection port), a porator array (comprising a top surface, a bottom surface, an extension tub, and a release liner), and a reservoir patch attached to the extension tub (the reservoir patch being applied to a microporated area of a tissue membrane after microporation). A method of making the system and a method of using the system are also provided.
摘要:
PROBLEM TO BE SOLVED: To provide an apparatus for treating congestive heart failure, renal failure, hyperpiesia and/or other cardiorenal disease using renal neuromodulation and/or renal denervation.SOLUTION: In a renal neuromodulation apparatus, a catheter with a spiral distal portion is configured to be transdarmally installed in a renal artery of a subject, the spiral distal portion is configured to come into contact with an inner surface of a wall of a renal artery after arrangement, and the catheter is configured to reduce generation of neural signal in a renal nerve close to the renal artery.
摘要:
An apparatus comprises an optically transparent electrode configured to provide transcutaneous electrical nerve stimulation to a user contacting a portion of an exterior surface of said apparatus proximal to said optically transparent electrode.